Beta cell function derived from routine clinical measures reports and predicts treatment response to immunotherapy in recent-onset type 1 diabetes. by Michelle So (400874)

“…A 6.2% decrease in Beta2 score at week 12 predicted significant improvement in HbA1c (-0.6% or -6 mmol/mol) and insulin use (-0.26 units/kg/day) in combined data from the rituximab, abatacept and anti-thymocyte globulin trials.…”

Table 4_Is takeout culture associated with rising colorectal cancer in young Chinese adults? An ecological analysis of GBD and CHNS data.xlsx by Ling Yao (16961)

“…</p>Results<p>The standardized incidence of Vitamin A deficiency has consistently declined over the past decade. …”

Table 1_Patient and donor antibody profiles in early COVID-19 convalescent plasma therapy in the COnV-ert trial.pdf by Andrea Alemany (11836601)

“…MB was associated with a significant decrease in cytophilic subclasses IgG1 and IgG3 to S and S2, and IgA to RBD, S and S2 in CCP units IgA to RBD, S and S2 in CCP units, without a reduction in neutralization titer and with a modest increase in IgG2 to RBD and S.…”

Image 3_Blastocystis infection in Tibetan antelopes (Pantholops hodgsonii) alters gut microbiota composition and function.tif by Jian Liu (33711)

“…Functional profiling showed a decrease in metabolic diversity, with 18 CAZy families detected in the healthy group but only 2 in the infected group. …”

Image 2_Blastocystis infection in Tibetan antelopes (Pantholops hodgsonii) alters gut microbiota composition and function.tif by Jian Liu (33711)

“…Functional profiling showed a decrease in metabolic diversity, with 18 CAZy families detected in the healthy group but only 2 in the infected group. …”

Exploring the protective role of DDIT4/mTOR in podocyte integrity through macrophage polarization in diabetic kidney disease by Jingxuan Shi (10807695)

“…<p>In this study, we explored the mechanism by which DDIT4 influences the polarization phenotypic transformation of macrophages and inflammation through the regulation of mTOR signaling pathway, providing a new mechanism and target for the treatment of diabetic nephropathy.…”

Image 4_Blastocystis infection in Tibetan antelopes (Pantholops hodgsonii) alters gut microbiota composition and function.tif by Jian Liu (33711)

“…Functional profiling showed a decrease in metabolic diversity, with 18 CAZy families detected in the healthy group but only 2 in the infected group. …”

Data_Sheet_1_Different responses of soil bacterial community to plant–plant interactions under organic–inorganic fertilizers affect seedling establishment during subalpine forest s... by Dandan Li (391591)

“…However, little knowledge is about the response of bacterial communities to plant–plant interaction and different fertilizers during secondary forest succession.</p>Methods<p>We conducted a field pot experiment applying organic and inorganic fertilizers to monocultures and mixed cultures of dominant plant species from mid- to late-successional stages (Salix oritrepha, Betula albosinensis, and Picea asperata), and investigated the responses of plant growth and rhizosphere bacterial communities.…”

Image 1_Blastocystis infection in Tibetan antelopes (Pantholops hodgsonii) alters gut microbiota composition and function.tif by Jian Liu (33711)

“…Functional profiling showed a decrease in metabolic diversity, with 18 CAZy families detected in the healthy group but only 2 in the infected group. …”

Table 1_Blastocystis infection in Tibetan antelopes (Pantholops hodgsonii) alters gut microbiota composition and function.xlsx by Jian Liu (33711)

“…Functional profiling showed a decrease in metabolic diversity, with 18 CAZy families detected in the healthy group but only 2 in the infected group. …”

Image 5_Blastocystis infection in Tibetan antelopes (Pantholops hodgsonii) alters gut microbiota composition and function.tif by Jian Liu (33711)

“…Functional profiling showed a decrease in metabolic diversity, with 18 CAZy families detected in the healthy group but only 2 in the infected group. …”

Ketamine wash-in. by Anne S. Fleiner (20496284)

“…(ii) The change in post-burst spiking after the wash-in of 20 μM and 100 μM was not significant compared to the control (MWU test). However, the decrease in post-burst spiking was significantly larger after the wash-in of 100 μM ketamine than with 20 μM (MWU test). …”

Image 1_Expansion of CD57+ CD8 T cells in common variable immunodeficiency with hepatopathy and CMV infection.pdf by Patrick Bez (13168041)

“…</p>Results<p>The expansion of CD57⁺ CD8 T cells was part of the previously described immune alteration, including altered CD4/CD8 ratio and a decrease in naïve CD4 T cells. The loss of significant association with increasing age might corroborate the suggestion of premature immunosenescence in CVID. …”

Table 1_Expansion of CD57+ CD8 T cells in common variable immunodeficiency with hepatopathy and CMV infection.pdf by Patrick Bez (13168041)

“…</p>Results<p>The expansion of CD57⁺ CD8 T cells was part of the previously described immune alteration, including altered CD4/CD8 ratio and a decrease in naïve CD4 T cells. The loss of significant association with increasing age might corroborate the suggestion of premature immunosenescence in CVID. …”

Raw_data_N_adition_increased_SOC_PNAS.xlsx by Guoyong Yan (14273351)

“…Thus, we conducted a long-term N addition experiment in a boreal forest to investigate whether and how N addition affects SOC, as well as how this effect is regulated by plant-soil-microbe synergies. …”

Addressing the Gap in Oncologist Training by Skylar Gay (20696057)

“…Experienced clinicians reviewed 135 randomly selected suboptimal examples to assess realism on a 5-point Likert scale.</p><p dir="ltr"><b>Results</b>: The algorithms successfully created radiotherapy dose distributions with decreased organs-at-risk sparing, decreased target conformality, and increased hotspots that were statistically significant (p<0.05) when assessed by dose-volume histogram metrics. …”

Image 1_Comparative analysis of cranberry fruit rot fungal diversity in Massachusetts from wild, organic, and conventional ecosystems using multiplex PCR.jpg by Salisu Sulley (22059035)

“…Organic bogs exhibited a significant decline in species richness from 6 fungi in 2021 to 2 fungi in 2022. …”

Data Sheet 1_The walking surface influences vertical ground reaction force and centre of pressure data obtained with pressure-sensing insoles.pdf by Elke Warmerdam (13895493)

“…When analysing gait data measured via insoles during daily living, we recommend to correct for the surface type to decrease variability.…”

Table 1_Association of spicy food consumption with colorectal polyp and adenoma prevalence: findings from the Lanxi Pre-Colorectal Cancer Cohort (LP3C).docx by Peiling Hu (12259394)

“…Objective<p>This study examined the relationship between habitual spicy food intake and the risk of colorectal polyps and adenomas in a high-risk Chinese cohort.</p>Methods<p>We analyzed baseline data from 14,907 participants aged 40–80 years enrolled in the Lanxi Precolorectal Cancer Cohort (LP3C) between March 2018 and December 2022. …”

Table 5_Active ingredients isolated from Periplaneta americana L. inhibit the inflammation of the colonic mucosa and regulate the gut microbiota in DSS-induced ulcerative colitis i... by Yanhuan Wang (12037016)

“…Furthermore, PA treatment attenuated intestinal dysbiosis in UC mice, characterized by an increase in beneficial bacteria (e.g., Psychrobacter) and a decrease in taxa like Actinobacteriota.</p>Conclusion<p>These findings collectively indicate that the aqueous extract of Periplaneta americana L. and its fractions possess significant therapeutic potential for UC treatment, with the unfractionated extract showing the most pronounced benefits via modulating inflammation, restoring barrier function, and rebalancing gut microbiota.…”