يعرض 5,501 - 5,520 نتائج من 5,845 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant ((we decrease) OR (a decrease)) ))~', وقت الاستعلام: 0.68s تنقيح النتائج
  1. 5501

    Data Sheet 1_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.pdf حسب Arjanneke F. van de Merbel (5809940)

    منشور في 2025
    "…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …"
  2. 5502

    Data Sheet 2_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.docx حسب Arjanneke F. van de Merbel (5809940)

    منشور في 2025
    "…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …"
  3. 5503

    SEAwise synthetic summary report of the findings of WP4 on changes to the ecosystem impacts of fishing in response to spatial management for online tool حسب Anna Rindorf (6217391)

    منشور في 2025
    "…Almost all management strategies except current management led to overall decreases in effort and as a result, the general ecosystem impact to a level where GES was attained (habitats and foodwebs) or the impact was decreased by at least 20% (bycatch). …"
  4. 5504

    Fertilization and herbivore exclusion promote more deterministic processes in plant community assembly on the Qinghai–Tibet Plateau حسب Wei Zhao (21458114)

    منشور في 2025
    "…However, the extent to which these factors influence the relative contributions of deterministic and stochastic processes in community assembly remains poorly understood. In this study, we conducted a five-year field experiment that manipulated nutrient availability and herbivore exclusion in an alpine grassland on the eastern Qinghai–Tibet Plateau. …"
  5. 5505

    Table 1_Predicting psychiatric risk: IgG N-glycosylation traits as biomarkers for mental health.xls حسب Yinchun Lv (18181816)

    منشور في 2024
    "…High levels of IGP21 were associated with an increased risk of post-traumatic stress disorder (PTSD), while elevated levels of IGP22 exhibited a causal association with a decreased risk of attention-deficit/hyperactivity disorder (ADHD). …"
  6. 5506

    Wheat germ agglutinin-nanoparticles encapsulating itacitinib target and suppress pro-inflammatory slan+ monocytes حسب Karen Alvarez (17620292)

    منشور في 2025
    "…<p>6-sulfoLacNAc (slan)+ monocytes, a non-classical monocyte subset, play a pro-inflammatory role in autoimmune diseases like systemic lupus erythematosus (SLE). …"
  7. 5507

    Data Sheet 1_Lysate of Parabacteroides distasonis prevents severe forms of experimental autoimmune encephalomyelitis by modulating the priming of T cell response.docx حسب Zuzana Jiraskova Zakostelska (6386825)

    منشور في 2024
    "…Pd lysate could thus be a future modulator of neuroinflammation that increases the resistance to multiple sclerosis.…"
  8. 5508

    Supplementary Material for: High expression of tetraspanin CD63 predicts poor prognosis in esophageal squamous cell carcinoma حسب Matsumoto Y. (2866151)

    منشور في 2025
    "…Herein, we report the significance of CD63 expression by analyzing ESCC patient samples and ESCC cell lines. …"
  9. 5509

    Data Sheet 1_Investigating the underlying mechanisms of the ethanol extract of saussureae involucratae herba in anti-rheumatoid arthritis effect based on sphingolipidomics.pdf حسب Pingyuan Chi (21563069)

    منشور في 2025
    "…In cell assays, SIE significantly decreased the protein levels of TNF-α and IL-6 (both P < 0.01) in LPS-stimulated RAW 264.7 cells. …"
  10. 5510

    All data. حسب Ke Li (106849)

    منشور في 2025
    "…Metabolomics analysis revealed that inulin treatment significantly modulated the levels of 8 stage-specific metabolites; notably, it increased anti-inflammatory, anti-diabetic and neuroprotective metabolites taurine and dodecanoic acid in prediabetic mice, while decreasing pro-inflammatory mediators including oleamide and adrenic acid. …"
  11. 5511

    Supplementary Material for: Splice variant of retinal G-protein-coupled receptor deletion (RGR-d)-mediated dysregulation of autophagy increases the susceptibility to age-related ma... حسب Guo Y. (2986464)

    منشور في 2024
    "…Beclin-1 and LC3II/I expression levels were significantly decreased and that of P62 was elevated in RGR-d cells after PA stimulation. …"
  12. 5512

    Table 1_Integrated multi-omics analysis reveals the mechanisms of naringin in ameliorating high-fat diet-induced metabolic dysfunction-associated steatotic liver disease.doc حسب Wenping Sun (1465360)

    منشور في 2025
    "…</p>Methods<p>In this study, we investigated the efficacy and underlying mechanisms of Nar in a mouse model of high-fat diet (HFD)-induced MASLD using integrated analyses of network pharmacology, molecular docking, hepatic lipidomics, and gut microbiota.…"
  13. 5513

    The inhibitory and anti-inflammatory effects of TMP269 on peste des petits ruminants virus replication حسب Miaomiao Li (483829)

    منشور في 2025
    "…The replication of many viruses is closely related to the regulation of histone deacetylases (HDACs). TMP269, a selective class IIa HDAC inhibitor, plays an important role in cancer therapy and also modulates viral replication. …"
  14. 5514

    Data_Sheet_1_Optimisation of Lactobacillus fermentation conditions and its application in the fermentation of salt-free sauerkraut.PDF حسب Wenlun Wang (18863641)

    منشور في 2024
    "…<p>To identify what are the dominant lactic acid bacteria (LAB) involved in the fermentation of salt-free sauerkraut, and optimize its industrial culture conditions, we isolated and identified a strain of LAB, which is referred to as Lactobacillus sp. …"
  15. 5515

    Data Sheet 1_Membrane filtration reduces nutrient availability and invasion potential in drinking water systems, without affecting mature biofilms.docx حسب Thomas Pluym (22046237)

    منشور في 2025
    "…In this study, we evaluated the efficacy of ultrafiltration (UF) and nanofiltration (NF) in reducing total organic carbon (TOC) and their impact on the microbiology in a pilot-scale drinking water distribution system over 7 weeks. …"
  16. 5516

    Data Sheet 1_MDSC depletion during immunization with heat-killed Mycobacterium tuberculosis increases protection against BCG infection.pdf حسب Arpa Aintablian (15648896)

    منشور في 2025
    "…Thus, we hypothesized that the defense against a subsequent BCG infection would be compromised in Mtb-immunized mice. …"
  17. 5517

    Data Sheet 1_Dual upregulation of miRNA-143 and miRNA-506 in non-small cell lung cancer inhibits proliferation, motility, migration, and tumor growth.pdf حسب Archana Shrestha (3641959)

    منشور في 2025
    "…Following stable transductions using lentiviruses in A549 and H1975 cells, we evaluated cell cycle distribution, proliferation, migration, and in vivo tumor growth. …"
  18. 5518

    Does policy integration in renewable energy deployment enhance environmental sustainability in Africa? حسب Mary Donkor (20463828)

    منشور في 2024
    "…<p>In recent years, the world has observed a steady rise in protective measures toward environmental sustainability, especially in developing countries like Africa, which is seen as a lower contributor to global pollution but is not exempted from the consequences of ozone layer depletion leading to global warming. …"
  19. 5519

    Data Sheet 1_Effect of high intakes of protein-only and carbohydrate-only on plasma metabolites and hormones, in addition to nitrogen excretion.xlsx حسب Matthieu Clauss (9769343)

    منشور في 2025
    "…The aims of this study were to compare the metabolic and hormonal responses to isocaloric intakes of whey protein alone versus carbohydrate alone. Additionally, we measured urinary nitrogen excretion as a marker of protein degradation.…"
  20. 5520

    Data_Sheet_1_Guanxin Danshen Formulation Protects against Myocardial Ischemia Reperfusion Injury-Induced Left Ventricular Remodeling by Upregulating Estrogen Receptor β.DOC حسب Xuehong Deng (13924952)

    منشور في 2024
    "…Target validation was conducted by using western blots and immunofluorescent double staining assays.</p><p>Results: We found that +dp/dt and LVSP were significantly elevated in the GXDSF-treated groups compared with the MIRI-LVR model group. …"