Data Sheet 1_A dual inhibitor of TrxR1 and XIAP induces pyroptosis in melanoma.docx by Yuan Wang (14955)

“…Previous studies have shown that both X-linked inhibitor of apoptosis (XIAP) and thioredoxin reductase 1 (TrxR1) participate in the resistance of melanoma to chemotherapy-induced cell death. In this study, we designed and synthesized a series of derivatives of natural compounds derived from Toona sinensis to simultaneously inhibit TrxR1 activity and destabilize the XIAP protein. …”

Supplementary Material for: Innovative regenerative treatment with Nanofat injection for hypertensive ischemic leg ulcer: a case report by figshare admin karger (2628495)

“…Case Presentation: We describe a 75-year-old female patient with a chronic ischemic ulcer measuring 30.1 cm² and persisting for more than 5 years. …”

The alien A<i>cacia salicina</i> invasive does not infiltrate the native soil rhizobial symbiosis networks by Mokhtar Rejili (17631037)

“…<p>Using <i>Lotus creticus</i>-rhizobia-<i>A. salicina</i> interaction networks, we address first the soil invasion success of <i>A. salicina</i>, and second, we report either <i>A. salicina</i>-rhizobia partnership should form an isolated module within the symbiosis interaction network. …”

Key Resources. by Jeffrey Chin (22538086)

“…Unexpectedly, we found that Tax1bp1-deficient mice were less susceptible to <i>Mtb</i> infection, and generated reduced inflammatory cytokine responses, compared to wild-type mice; the same mutant mice exhibited decreased growth of, and inflammatory cytokine responses to, <i>Listeria monocytogenes</i>, suggesting that Tax1bp1 plays a role in host responses to multiple intracellular pathogens. …”

Tax1bp1-deficiency reduces autophagy flux. by Jeffrey Chin (22538086)

“…Unexpectedly, we found that Tax1bp1-deficient mice were less susceptible to <i>Mtb</i> infection, and generated reduced inflammatory cytokine responses, compared to wild-type mice; the same mutant mice exhibited decreased growth of, and inflammatory cytokine responses to, <i>Listeria monocytogenes</i>, suggesting that Tax1bp1 plays a role in host responses to multiple intracellular pathogens. …”

Table 1_ZmEXPB7, a β-expansin gene, contributes to drought tolerance in Arabidopsis.docx by Jing Xiong (218613)

“…<p>Drought stress poses a significant threat to maize productivity, highlighting the need to elucidate molecular mechanisms underlying drought tolerance. …”

Table 2_Cost-effectiveness of the 3E model in diabetes management: a machine learning approach to assess long-term economic impact.docx by Supriya Raghav (21412907)

“…</p>Results<p>The 3E model demonstrated significant cost reductions, with the intervention group achieving a 74.3% decrease in total costs compared to 41.8% in the control group while maintaining the same level of glycemic control. …”

Table 1_Cost-effectiveness of the 3E model in diabetes management: a machine learning approach to assess long-term economic impact.xlsx by Supriya Raghav (21412907)

“…</p>Results<p>The 3E model demonstrated significant cost reductions, with the intervention group achieving a 74.3% decrease in total costs compared to 41.8% in the control group while maintaining the same level of glycemic control. …”

Table 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx by Lili Zhou (265076)

“…Cellular experiments further investigated the expression of cholesterol metabolism-related proteins and the effect of the cholesterol-depleting agent Methyl-β-cyclodextrin (MβCD) on DLBCL cells.</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …”

Table 2_Mortality and trends of pulmonary arterial hypertension, 1990–2021: a population-based study.docx by Linhong Jiang (5004347)

“…Background<p>Pulmonary arterial hypertension (PAH) is a progressive disease associated with high fatality rate. …”

Table 1_Mortality and trends of pulmonary arterial hypertension, 1990–2021: a population-based study.docx by Linhong Jiang (5004347)

“…Background<p>Pulmonary arterial hypertension (PAH) is a progressive disease associated with high fatality rate. …”

Table 3_Mortality and trends of pulmonary arterial hypertension, 1990–2021: a population-based study.docx by Linhong Jiang (5004347)

“…Background<p>Pulmonary arterial hypertension (PAH) is a progressive disease associated with high fatality rate. …”

Efficacy and safety of anticoagulation in asymptomatic cirrhotic patients with portal vein thrombosis: a systematic review and meta-analysis by Qingping Wu (789611)

“…Compared to no intervention, anticoagulation significantly increased the PVT recanalization rate (OR = 3.89, <i>p</i> < .001) and decreased the PVT progression rate (OR = 0.28, <i>p</i> < .001) as well as overall mortality (OR = 0.66, <i>p</i> = .008). …”

Table 1_Changes in taste perception in elderly population and its potential impact on oral health: a systematic review with meta-analysis.docx by Larisse Santos Mendonça Alves (20386377)

“…This is expected with aging due to a decrease in taste buds and other conditions, leading to systemic and oral diseases. …”

Table 1_Efficacy of submucosal administration of tramadol on acute pain following third molar surgery: a systematic review and meta-analysis.docx by Ahmad Salem Assari (20277900)

“…In addition, tramadol demonstrated a significant decrease in post-operative pain.</p>Conclusion<p>Submucosal tramadol is an efficient, safe, and dependable method for reducing post-operative acute pain, particularly in the first 6 h following impacted third molar surgery. …”

Data Sheet 1_Microbial dysbiosis in obstructive sleep apnea: a systematic review and meta-analysis.docx by Yang Guo (399435)

“…Background<p>The association between the microbiota and obstructive sleep apnea (OSA) remains understudied. In this study, we conducted a comprehensive systematic review and meta-analysis of studies investigating the diversity and relative abundance of microbiota in the gut, respiratory tracts and oral cavity of patients with OSA, aiming to provide an in-depth characterization of the microbial communities associated with OSA.…”

Scheme of g-λ model with larger values λ. by Zhanfeng Fan (20390992)

“…The findings suggest that when λ is respectively equal to 4.19, 8.57, 10, and 12.15, the peak particle velocity (PPV) of the transmitted waves is significantly close to the incident wave amplitude. Furthermore, when λ is fixed, the energy transmission coefficient increases with the incident wave amplitude but decreases with the incident wave frequency. …”

Supplementary file 1_Use of erythromycin and metoclopramide in hospitalized dogs: a multicenter historical cohort study.docx by Ee Fung Teo (21181196)

“…There were also significant differences in prokinetic use between institutions.…”

Image4_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff by Alexandra Coello-Camba (6489533)

“…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”

Supplementary file 2_Use of erythromycin and metoclopramide in hospitalized dogs: a multicenter historical cohort study.pdf by Ee Fung Teo (21181196)

“…There were also significant differences in prokinetic use between institutions.…”