Table 5_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.docx by Zhijian Zha (19451405)

“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”

Table 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx by Rong Su (2210740)

“…In vitro, the overexpression of miR-4739 in Huh-7 cells significantly induced SPP1⁺ macrophages, and the culture medium derived from SPP1⁺ macrophages further promoted the proliferation and migration of Huh-7 cells. …”

DataSheet2_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf by Jianan Zhang (786459)

“…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …”

Supplementary file 1_Oral bacterial community dynamics during induction of gingival inflammation.docx by Bart J. F. Keijser (16884185)

“…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …”

Presentation 1_Anti-PD1 therapies induce an early expansion of Ki67+CD8+ T cells in metastatic non-oncogene addicted NSCLC patients.pptx by Alain Gelibter (6409364)

“…Concurrently, 14 soluble immune checkpoints were analyzed by Luminex assay. Immunotherapy significantly increased the levels of Ki67⁺(total and CD8⁺) T cells, PMN(Lox1⁺)-MDSCs, non-suppressive Tregs (nsTregs), and soluble PD1 from T0 to T1 in the entire NSCLC population, while decreased active Tregs. …”

Glucagon-like peptide-1 receptor agonists, inflammation, and kidney diseases: evidence from Mendelian randomization by Yu-Xuan Yao (21338594)

“…</p> <p>After meta-analyses of both discovery and validation cohorts, genetically proxied GLP1R agonist was found to significantly associated with a decreased risk of diabetic nephropathy (OR = 0.72, 95%CI = 0.54–0.97, <i>p</i> = 0.031) and IgA nephropathy (OR = 0.58, 95%CI = 0.36–0.94, <i>p</i> = 0.027). …”

Data Sheet 1_Impact of fatigue in Crohn's disease is negatively related to resting state functional connectivity between the superior parietal lobule and parahippocampal gyrus/hipp... by Theresa A. McIver (21178337)

“…</p>Discussion<p>In people with Crohn's disease, fatigue increases as functional connectivity between brain regions involved in sensorimotor integration and memory processing decreases.</p>…”

Analyzing the global burden of 11 subtypes of congenital birth defects: trends, sociodemographic correlates, and outcomes from 1990 to 2021 by Enhui Yang (11844002)

“…</p> <p></p><p>The prevalence, mortality, and DALYs attributable to congenital birth defects (CBDs) significantly decreased globally from 1990 to 2021, though notable regional disparities persist.…”

Table 1_Leaf senescence characteristics and economic benefits of rice under alternate wetting and drying irrigation and blended use of polymer-coated and common urea.docx by Dongliang Qi (3228141)

“…This suggested that AWD combined with N2 and N3 could delay the leaf senescence of rice, thus achieving a larger grain yield. Moreover, AWD significantly decreased water costs (irrigation amount) and labor costs (irrigation frequency), thus increasing total income. …”

DataSheet1_An observational study of lower limb muscle imbalance assessment and gait analysis of badminton players.docx by Ping Huang (30439)

“…Lower limb muscle imbalance can cause gait abnormalities and increase the risk of muscle injury or decreased performance in significantly asymmetrical situations. …”

Developmental change in 5-HT_1A binding in known cause of death controls (predischarge and postdischarge combined). by Hannah C. Kinney (10280975)

“…Binding in these nuclei are visually (top row) and quantitatively (bottom row) decreasing with PC age, the latter shown with plots of 5-HT_1A binding vs PC age. …”

<i>Tg</i>ATM1-depleted <i>Toxoplasma</i> are functionally complemented through expression of the <i>Plasmodium</i> or yeast homolog. by Deepti Shrivastava (17715780)

“…The number of significantly increased and decreased proteins is given and the NEET proteins CDGSH1 and CDGSH2 as well as <i>Tg</i>ATM1 are indicated.…”

Differential mRNA expression of key metabolic and stress response genes in the <i>MYH7</i> Q315R mice. by Shinya Takarada (8655066)

“…Clustering maps show significant changes in RNA expression (p < 0.05) greater than twofold or less than −2.0-fold (A and C). …”

The protective effects of neferine against paracetamol-induced liver injury are associated with the activation of SIRT1/Nrf2/HO-1 signaling pathway and inhibition of NF-kappa B/TNF... by Mohammed A. Altowijri (22461945)

“…<p>Drug-induced hepatotoxicity is a significant public health issue that influences the development of novel pharmaceutical therapies and the retraction of numerous promising medications from the market. …”

Supplementary file 1_Cell wall modulation by drought and elevated CO2 in sugarcane leaves.docx by Alexandre Junio Borges Araujo (12977867)

“…<p>Climate change poses significant challenges to global agriculture, with elevated atmospheric CO2 (eCO₂) concentrations and increased frequency of droughts affecting crop productivity. …”

Supplementary file 3_The interventional effect of astragaloside IV on rodent models of myocardial fibrosis: a systematic review and meta-analysis.doc by Haozhe Li (6399116)

“…However, it exerted no significant impact on the levels of LVIDs and LVIDd in the model.…”

<i>DANCR</i> is a clinically important MITF and c-MYC regulated lncRNA in human melanoma. by Stephanie M. E. Jones (12883691)

“…Cox regression analysis shows that high <i>DANCR</i> expression correlates with statistically significant decreased survival (logrank p-value = 0.00628).…”

Data Sheet 3_Cell wall modulation by drought and elevated CO2 in sugarcane leaves.xlsx by Alexandre Junio Borges Araujo (12977867)

“…<p>Climate change poses significant challenges to global agriculture, with elevated atmospheric CO2 (eCO₂) concentrations and increased frequency of droughts affecting crop productivity. …”

Data Sheet 4_Cell wall modulation by drought and elevated CO2 in sugarcane leaves.xlsx by Alexandre Junio Borges Araujo (12977867)

“…<p>Climate change poses significant challenges to global agriculture, with elevated atmospheric CO2 (eCO₂) concentrations and increased frequency of droughts affecting crop productivity. …”

Impairing lipolysis in <i>An</i>. <i>gambiae</i> females induces severe embryonic lethality. by Maurice A. Itoe (9930475)

“…(F, G) Injection of dsAg<i>LSD</i>1 (F) significantly reduces the number of eggs laid and (G) severely decreases survival rates (Mann–Whitney test). …”