Table 2_Astragaloside IV alleviates GDM via regulating gut microbiota and gut microbiota metabolomic.xlsx حسب Fengge Wang (4347442)

"…</p>Results<p>After the 25-day intervention, the GDM model + AS IV group showed significantly decreased fasting blood glucose levels (p = 0.0003), mean insulin levels (p = 0.0001), and insulin resistance index (p = 0.0001). …"

Table 1_Effectiveness and safety of hydrogen inhalation therapy as an additional treatment for hypertension in real-world practice: a retrospective, observational study in China.do... حسب Hongxiang Ji (11235519)

"…</p>Results<p>In total, we selected 2,364 patients into the analysis. Both mean SBP and DBP levels significantly decreased in the HI group compared to control group at each follow-up visit with the between group difference of −4.63 mm Hg (95% CI, −6.51 to −2.74) at week 8, −6.69 mm Hg (95% CI, −8.54 to −4.85) at week 16, −7.81 mm Hg (95% CI, −9.57 to −6.04) at week 24 for SBP, and −1.83 mm Hg (95% CI, −3.21 to −0.45) at week 8, −2.57 mm Hg (95% CI, −3.97 to −1.17) at week 16, −2.89 mm Hg (95% CI, −4.24 to −1.54) at week 24 for DBP. …"

Data Sheet 1_Associations between obesity and arterial stiffness assessed by cardio-ankle vascular index in healthy children and adolescents.docx حسب Yuko Horikoshi (12202859)

"…</p>Methods<p>This was a cross-sectional study conducted in 2024. We evaluated CAVI and its associated factors in 590 children aged 6–15 years (mean age: 10.5 years, 51.0% female). …"

Data Sheet 1_Top motor and non-motor complaints in patients with Parkinson's disease.docx حسب José Fidel Baizabal-Carvallo (11416508)

"…Responses were divided into three tiers.</p>Results<p>We studied 230 consecutive patients with PD. There were 130 (56.5%) male patients, with the mean age at evaluation of 67.7 ± 11.06 years. …"

Identification of novel pathogenic mutations in <i>ATP6V0A4</i> associated with distal renal tubular acidosis and analysis of wild-type expression in glomerular disease حسب Yaru Jiang (17458815)

"…If untreated, it can result in a significant electrolyte imbalance and progressive chronic kidney disease (CKD). …"

Supplementary file 1_Soluble suppression of tumorigenicity-2 changes during cardiotoxic cancer treatment: a systematic review and meta-analysis.docx حسب Luca Fazzini (22599380)

"…Using random-effects models, mean differences (MD), and standardized MD (SMD), we analyzed (i) ST2 longitudinal changes, (ii) the association between ST2 and cardiotoxicity [defined through left ventricular ejection fraction (LVEF)] providing pooled estimates of correlations, and (iii) the SMD variations among biomarkers.…"

Roxadustat has risks of reversible central hypothyroidism in patients undergoing hemodialysis: a single-center retrospective cohort study حسب Emiko Otsuka (7519313)

"…The prevalence and reversibility of roxadustat-induced central hypothyroidism in patients undergoing hemodialysis remain unclear. Here, we retrospectively analyzed thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) levels in 51 patients (mean age: 72.3 ± 10.7 years; 58.8% male) undergoing hemodialysis before, during, and after halting roxadustat treatment. …"

Table 1_Effect of cholecalciferol on immune and vascular function in non-diabetic chronic kidney disease.docx حسب Kajal Kamboj (12769602)

"…</p>Results<p>In total, 62 subjects were studied. The mean age was 44 ± 12 years with 58% men. TH1 cells decreased from 17% (9%, 27%) to 11% (6%, 16%) (p=0.002) and TH2 cells increased from 9% (5%, 16%) to 16% (10%, 27%) (p=0.001) after cholecalciferol treatment. …"

Table 1_The knowledge paradox: an inverted U-shaped association between HIV knowledge and stigma among older men in Sichuan Province, Southwest China.docx حسب Zhihua Ye (3133311)

"…</p>Results<p>The weighted mean HIV knowledge score was 4.39 (SD = 2.13), and the weighted mean stigma score was 31.78 (SD = 5.60). …"

DataSheet1_Probiotics combined with prebiotics alleviated seasonal allergic rhinitis by altering the composition and metabolic function of intestinal microbiota: a prospective, ran... حسب Yangfan Hou (8043884)

"…From baseline to day 91, mean difference between groups (MDBG) in the reduction of TNSS was -1.1 (-2.2, -0.1) (P = 0.04); MDBG in the increment of TNF-α was 7.1 pg/ml (95% CI: 0.8, 13.4, P = 0.03); the INF-γ level was significantly increased (P = 0.01), whereas that of IL-17 (P = 0.005) was significantly decreased in the test group, whilst mean difference within groups was not statistically significant in the placebo group; MDBG in the increment of acetate was 12.4% (95% CI: 7.1%, 17.6%, P <0.001). …"

Glucagon-like peptide 1 receptor agonists modestly reduced low-density lipoprotein cholesterol and total cholesterol levels independent of weight reduction: a meta-analysis and met... حسب Frederick Berro Rivera (12679463)

"…</p> <p>GLP-1RA treatment modestly decreased LDL-C and TC but did not significantly affect triglycerides, VLDL-C, or HDL-C.…"

Data Sheet 1_Beta tACS of varying intensities differentially affect resting-state and movement-related sensorimotor power.docx حسب Kym Wansbrough (19711762)

"…For event-related activity, we observed intensity-dependent changes in bilateral broadband power (4–90 Hz): during movement preparation, 1.0 mA stimulation increased power; during movement termination, 0.5 mA stimulation decreased power while 1.0 mA and 1.5 mA stimulation induced comparable increases in power. …"

Table 1_Clinical outcomes and psychosomatic correlates of integrative inpatient care based on Traditional Korean Medicine for acute neck and low back pain following traffic acciden... حسب Yohwan Kim (5482454)

"…</p>Results<p>One hundred ninety patients were analyzed. Significant improvements were observed, with mean changes in axial, neck, and low back pain of 2.09, 2.21, and 1.94 (all p < 0.05). …"

Data Sheet 1_Electroacupuncture treatment can improve cognitive impairment in spontaneously hypertensive rats: a preliminary DTI study.docx حسب Ji-peng Liu (14764009)

"…</p>Results<p>The results showed that electroacupuncture significantly decreased systolic and diastolic blood pressure and enhanced spatial learning and memory in SHRs. …"

Table 1_Eculizumab for the acute attack of neuromyelitis optica spectrum disorder.docx حسب Qingqing Zhuang (22109089)

"…Visual field mean deviation improved from −22.4 dB to −2.0 dB (p = 0.008). …"

EU Data.csv<b>EU Data-1:</b> Age, sex, and medications used in patients with Parkinson’s disease.<b>EU Data-2:</b> Experimental parameters during off and on states of anti-Parkinso... حسب Eiichirou Urasaki (20502995)

"…The rate of CSP duration shortening during cold pressure was significantly greater under the drug-on condition than under the drug-off condition (mean, 22% vs. 12%; p < 0.01). …"

Table 1_Obinutuzumab in systemic lupus erythematosus: a real-world experience.docx حسب Chunmei Wu (3202050)

"…By week 48, 37.5% achieved DORIS remission, 32.1% LLDAS, and 19.6% remained clinically stable. Mean SLEDAI-2K decreased from 11.75 ± 9.31 (range: 0 to 46) to 1.45± 1.93 (range: 0 to 8). …"

Supplementary Material for: Head positioning for stroke blood flow augmentation assisting reperfusion therapies (HEAD-START) study حسب figshare admin karger (2628495)

"…Trendelenburg positioning was maintained for 24h if lesion volume significantly decreased (≥5mL) and stroke reperfusion was suboptimal or undetermined. …"

Data Sheet 1_Real world evidence of dupilumab effectiveness in a Colombian cohort of patients diagnosed with severe asthma.docx حسب Abraham Alí-Munive (21347201)

"…FEV1 measurements after one or two years of dupilumab treatment were significantly lower than baseline (p = 0.03). Mean change from baseline in FEV₁ was 302.1 ± 481.97 ml (n = 19), 282.00 ± 231.99 ml (n = 10), and 248.18 ± 281.21 ml (n = 11) in the 2–4-, 11–13-, and 19–25-month follow-up periods, respectively. …"

Table6_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx حسب J. Riera-Arnau (20431328)

"…</p>Results<p>A total of 400 patients were included (17.3% pediatric), with a mean follow-up of 122.1/person-years for adults. …"