Efficacy and safety of trastuzumab deruxtecan in HER2-high and HER2-low breast cancer: a systematic review and meta-analysis of randomized controlled trials by Sheng-Yen Hsiao (9939006)

“…However, T-DXd increased the risks of interstitial lung disease (relative risk [RR] = 13.832; P < 0.001), decreased left ventricular ejection fraction (RR = 2.247; P < 0.001), anemia, nausea, vomiting, decreased appetite, and alopecia; neutropenia and diarrhea risks were comparable between groups. …”

Image 1_The microbiome exists in the neuroretina and choroid in normal conditions and responds rapidly to retinal injury.tif by Xuexue Cui (11574637)

“…In the RPE/choroid, the abundance of Actinomyces and Roseburia decreased, and the abundance of Lactobacillus increased significantly after laser injury. …”

Data Sheet 1_Epigallocatechin gallate (EGCG) modulates senescent endothelial cell-monocyte communication in age-related vascular inflammation.docx by Sarvatit Patel (5558792)

“…<p>Aging significantly affects intercellular communication between vascular endothelial cells (ECs) and hematopoietic cells, leading to vascular inflammation and age-associated diseases. …”

Table 1_Exogenous jasmonic acid and salicylic acid enhance selenium uptake and mitigate cadmium accumulation in pak choi (Brassica chinensis L.) grown in selenium-rich, high-cadmiu... by Jin-Ping Chen (6003755)

“…Cd accumulation in shoots decreased by 11.7%-29.3% in JA-containing treatments, with the same combined producing the lowest shoot Cd levels. …”

Image 1_Enhancing yield and quality: research and practice of agro-forest waste for Lentinus edodes (shiitake mushroom) cultivation.jpg by Hongyan Xu (29047)

“…The weight of mushrooms produced from all agro-forest waste substrates was significantly lower than that of the control group, decreasing by 18.96 to 53.88%. …”

Table 1_Associations between physical activity and cardiorespiratory fitness and adverse outcomes in patients with atrial fibrillation: a prospective cohort study.pdf by Yanwen Chen (460790)

“…All levels of PA were significantly associated with a decreased risk of cardiovascular death with HRs ranging from 0.577 to 0.938 (P < 0.01). …”

Table 2_Associations between physical activity and cardiorespiratory fitness and adverse outcomes in patients with atrial fibrillation: a prospective cohort study.pdf by Yanwen Chen (460790)

“…All levels of PA were significantly associated with a decreased risk of cardiovascular death with HRs ranging from 0.577 to 0.938 (P < 0.01). …”

Supplementary file 1_Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis.doc by Zhenghao Wu (9732511)

“…For in vitro experiments, hepatic stellate cells, macrophages and lymphatic endothelial cells were used to observe the multiple effects of FN.</p>Results<p>FN significantly ameliorated portal pressure in cirrhosis-induced PHT, improved liver function, and reduced liver fibrosis and hepatic stellate cell activation with decreased SMAD3 protein expression. …”

Image 2_Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone.jpeg by Zetong Zheng (22069658)

“…LH, but not E2, significantly induced AQP2 expression in LGCs in a dose-dependent manner. …”

Baseline characteristics of the four groups. by Chao Yang (174810)

“…When the HAR was lower than 0.13, mortality within 28 days after ICU admission decreased significantly as the HAR increased. When the HAR was higher than 0.13, the HAR was not a protective factor for mortality within 28 days after ICU admission. …”

Flow of included patients through the trial. by Chao Yang (174810)

“…When the HAR was lower than 0.13, mortality within 28 days after ICU admission decreased significantly as the HAR increased. When the HAR was higher than 0.13, the HAR was not a protective factor for mortality within 28 days after ICU admission. …”

Data Sheet 1_Ginsenoside Ro ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via the IBA1/GFAP-MAPK signaling pathway.docx by Tianyao Li (7388201)

“…It also decreased Aβ deposition and ameliorated neuronal apoptosis in the cerebral cortex. …”

Image 1_Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone.tif by Zetong Zheng (22069658)

“…LH, but not E2, significantly induced AQP2 expression in LGCs in a dose-dependent manner. …”

Table 1_Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone.docx by Zetong Zheng (22069658)

“…LH, but not E2, significantly induced AQP2 expression in LGCs in a dose-dependent manner. …”

The efficacy of metformin in counteracting olanzapine-induced hyperprolactinemia: an open-label prospective study by Kah Kheng Goh (4983368)

“…</p> <p>After eight weeks of metformin intervention, prolactin levels significantly decreased from 39.7 ± 20.0 ng/mL at baseline to 35.7 ± 15.7 ng/mL (<i>p</i> = 0.005) with a moderate effect size (Cohen’s <i>d</i> = 0.545). …”

Data Sheet 1_NLRP3 regulates epithelial barrier integrity and protects from airway hyperresponsiveness in experimental allergic asthma.pdf by Stephanie DeStefano (15457187)

“…Analysis of epithelial cell markers revealed decreased gene expression of the tight junction proteins Cld-18 and Tjp-1, and decreased expression of the epithelial transmembrane protein E-cadherin in the lungs of naïve NLRP3^-/- mice compared to WT mice. …”

Cox proportional hazards modeling. by Chao Yang (174810)

“…When the HAR was lower than 0.13, mortality within 28 days after ICU admission decreased significantly as the HAR increased. When the HAR was higher than 0.13, the HAR was not a protective factor for mortality within 28 days after ICU admission. …”

<b>Data for opposing effects</b><b> of maize straw and its biochar on soil N</b>_{<strong>2</strong>}<b>O emissions</b><b> </b><b>by mediating microbial nitrification and d... by MOULIANG XIAO (21266015)

“…<p dir="ltr">Application of straw and biochar has been shown to significantly affect greenhouse gas emissions from soil. …”

Table 1_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…In MAFLD mice, TFA treatment significantly decreased body weight gain, hepatic lipid accumulation, and the serum levels of ALT, AST, TC, and TG. …”

Table 2_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…In MAFLD mice, TFA treatment significantly decreased body weight gain, hepatic lipid accumulation, and the serum levels of ALT, AST, TC, and TG. …”