Showing 2,021 - 2,040 results of 2,040 for search '(( significant decrease decrease ) OR ( significant (challenge OR challenges) decrease ))~', query time: 0.41s Refine Results
  1. 2021

    Table 3_Efgartigimod for the treatment of immune checkpoint inhibitor-associated myocarditis complicated with impending crisis state of myasthenia gravis: a case report.docx by Mingjia Lu (21593324)

    Published 2025
    “…Treatment with efgartigimod (10 mg/kg) significantly improved myasthenic symptoms, with Myasthenia Gravis–Activities of Daily Living (MG-ADL) and Quantitative Myasthenia Gravis (QMG) scores decreasing from 11 to 5 and 26 to 11, respectively. …”
  2. 2022

    Data Sheet 3_Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke.zip by Fengli Ye (22123540)

    Published 2025
    “…Due to ambiguous symptoms and limited biomarkers, early diagnosis and prognosis remain challenging. Recent evidence suggests that gut microbiota dysregulation influences neuroinflammation and outcomes in ICH, but the underlying molecular mechanisms remain unclear.…”
  3. 2023

    A platform for the rapid screening of equine immunoglobins F (ab)2 derived from single equine memory B cells able to cross-neutralize to influenza virus by Yuezhi Lin (9287759)

    Published 2024
    “…Furthermore, it effectively protected EIV-challenged mice, resulting in significantly improved survival, reduced pulmonary inflammation and decreased viral titers. …”
  4. 2024

    Data Sheet 1_Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke.zip by Fengli Ye (22123540)

    Published 2025
    “…Due to ambiguous symptoms and limited biomarkers, early diagnosis and prognosis remain challenging. Recent evidence suggests that gut microbiota dysregulation influences neuroinflammation and outcomes in ICH, but the underlying molecular mechanisms remain unclear.…”
  5. 2025

    Data Sheet 2_Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke.zip by Fengli Ye (22123540)

    Published 2025
    “…Due to ambiguous symptoms and limited biomarkers, early diagnosis and prognosis remain challenging. Recent evidence suggests that gut microbiota dysregulation influences neuroinflammation and outcomes in ICH, but the underlying molecular mechanisms remain unclear.…”
  6. 2026

    Data Sheet 1_Efficacy and safety of anlotinib combined with 125I seed implantation for iodine-refractory thyroid cancer.docx by Zhijun Chen (254277)

    Published 2025
    “…Background and objective<p>Radioiodine-refractory differentiated thyroid cancer (RAIR-DTC) remains challenging to treat due to a lack of effective therapies. …”
  7. 2027

    Image 1_A four-gene signature identified by integrated transcriptomic analysis for differential diagnosis and prognosis of uterine smooth muscle tumors.pdf by Huiyi Hu (11226995)

    Published 2025
    “…Moreover, survival analysis revealed the prognostic significance of this four-gene signature: high TOP2A with low ABLIM1, FHL5, and MAP3K8 expression correlated with decreased overall survival in ULMS, implicating their potential role as diagnostic and prognostic markers. …”
  8. 2028

    Table 1_Therapeutic potential of Triptolide in inhibiting breast cancer-induced bone destruction – PTHrP as a therapeutic target.docx by Wu Di (11561998)

    Published 2025
    “…Introduction<p>Bone metastases are a common and severe complication in advanced breast cancer, affecting approximately 65% to 70% of patients and significantly reducing survival time. Osteolytic bone metastases, in particular, are challenging to manage due to their association with skeletal-related events (SREs) that accelerate disease progression and diminish the quality of life. …”
  9. 2029

    Data Sheet 1_Characterization of the Vibrio anguillarum VaRyhB regulon and role in pathogenesis.docx by Yingjie Li (2106778)

    Published 2025
    “…The virulence of VaRyhB was evaluated by challenging turbot larvae intraperitoneally. </p>Results<p>The small RNA called VaRyhB identified in V. anguillarum strain 775 is significantly longer than that in Escherichia coli. …”
  10. 2030

    Table 2_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.xlsx by Tong Luo (458639)

    Published 2025
    “…</p>Results<p>CNS significantly improved survival, reduced pulmonary edema, and alleviated lung inflammation and locomotor deficits in LPS-challenged mice. …”
  11. 2031

    Table 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.xlsx by Tong Luo (458639)

    Published 2025
    “…</p>Results<p>CNS significantly improved survival, reduced pulmonary edema, and alleviated lung inflammation and locomotor deficits in LPS-challenged mice. …”
  12. 2032

    <b>Combination of isobavachalcone and amphotericin B has antifungal effect against </b><b>Cryptococcus neoformans</b><b>and protects host tissue damage by inhibiting ferroptosis</b... by Weidong Qian (20813608)

    Published 2025
    “…The development of novel therapeutic strategies is imperative, albeit challenging. A promising approach involves the synergistic interaction between existing antifungal agents and supplements to enhance efficacy, reduce dosages, and mitigate resistance. …”
  13. 2033

    Table 1_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx by Qiqi Wu (4895728)

    Published 2025
    “…Compared with control interventions, acupuncture significantly reduced VAS scores, decreased the frequency and duration of migraine attacks, and improved response rates, as well as HIT-6 and MHI scores. …”
  14. 2034

    Image 4_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

    Published 2025
    “…</p>Results<p>CNS significantly improved survival, reduced pulmonary edema, and alleviated lung inflammation and locomotor deficits in LPS-challenged mice. …”
  15. 2035

    Supplementary file 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.docx by Tong Luo (458639)

    Published 2025
    “…</p>Results<p>CNS significantly improved survival, reduced pulmonary edema, and alleviated lung inflammation and locomotor deficits in LPS-challenged mice. …”
  16. 2036

    Image 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

    Published 2025
    “…</p>Results<p>CNS significantly improved survival, reduced pulmonary edema, and alleviated lung inflammation and locomotor deficits in LPS-challenged mice. …”
  17. 2037

    Image 2_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

    Published 2025
    “…</p>Results<p>CNS significantly improved survival, reduced pulmonary edema, and alleviated lung inflammation and locomotor deficits in LPS-challenged mice. …”
  18. 2038

    Image 3_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

    Published 2025
    “…</p>Results<p>CNS significantly improved survival, reduced pulmonary edema, and alleviated lung inflammation and locomotor deficits in LPS-challenged mice. …”
  19. 2039

    Table 2_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx by Qiqi Wu (4895728)

    Published 2025
    “…Compared with control interventions, acupuncture significantly reduced VAS scores, decreased the frequency and duration of migraine attacks, and improved response rates, as well as HIT-6 and MHI scores. …”
  20. 2040

    Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX by Cataldo Martucci (3117069)

    Published 2024
    “…In a murine house dust mite (HDM) model of asthma exacerbated by influenza virus A (IAV) (H3N3), CHF6297 (0.1 mg/kg, i.n.) significantly decreased airway neutrophilia compared to vehicle-treated IAV/HDM-challenged mice. …”