يعرض 1,041 - 1,060 نتائج من 2,040 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant (challenge OR challenges) decrease ))~', وقت الاستعلام: 0.30s تنقيح النتائج
  1. 1041

    Marketed vaccines against canine leishmaniasis. حسب Llum Páez (22553360)

    منشور في 2025
    "…The development of a vaccine against leishmaniasis is a challenging objective in veterinary medicine due to the parasite’s life cycle complexity, resistance, relapses, and toxicity of the currently available drugs. …"
  2. 1042

    Data Sheet 1_Prevalence trend and burden of foodborne trematodiasis in China from 1990 to 2021 and its predictions until 2030: a comparative study with Japan and South Korea.csv حسب Runzhou Ma (19758996)

    منشور في 2025
    "…Background<p>Foodborne trematodiasis (FBT) poses a significant public health challenge in East Asia, influenced by local dietary practices and environmental conditions. …"
  3. 1043

    Presentation 1_Prevalence trend and burden of foodborne trematodiasis in China from 1990 to 2021 and its predictions until 2030: a comparative study with Japan and South Korea.pdf حسب Runzhou Ma (19758996)

    منشور في 2025
    "…Background<p>Foodborne trematodiasis (FBT) poses a significant public health challenge in East Asia, influenced by local dietary practices and environmental conditions. …"
  4. 1044

    Data Sheet 2_Prevalence trend and burden of foodborne trematodiasis in China from 1990 to 2021 and its predictions until 2030: a comparative study with Japan and South Korea.docx حسب Runzhou Ma (19758996)

    منشور في 2025
    "…Background<p>Foodborne trematodiasis (FBT) poses a significant public health challenge in East Asia, influenced by local dietary practices and environmental conditions. …"
  5. 1045

    Data Sheet 1_Safety and immunomodulatory efficacy of heat-killed Mycolicibacterium manresensis as a novel paraprobiotic in swine.pdf حسب Carmen Álvarez-Delgado (18964264)

    منشور في 2025
    "…Piglets supplemented with higher doses of hkMm exhibited a significant increase in salivary adenosine deaminase levels (p = 0.0042), along with a significant decrease in serum haptoglobin concentration (p = 0.0263). …"
  6. 1046

    Table 1_Are alternatively organized value chains more environmentally sustainable? Evidence from soybean production in Minas Gerais and Paraná states, Brazil.docx حسب Réussite Bugale Malembaka (22569818)

    منشور في 2025
    "…<p>The predominant agro-industrial soybean production in Brazil has led to a significant socio-ecological crisis. Alternative agriculture has been increasingly marketed as a viable solution to the multifaceted challenges engendered by this intensive production system in the Atlantic Forest biome of Brazil and its related global value chains. …"
  7. 1047

    Table 1_Burden of esophageal cancer in global, regional and national regions from 1990 to 2021 and its projection until 2050: results from the GBD study 2021.docx حسب Chengcheng Zhang (725743)

    منشور في 2025
    "…</p>Conclusions<p>The global burden of EC remains significant, with ongoing challenges in regions such as Africa and East Asia. …"
  8. 1048

    Computed tomography-guided radiofrequency ablation of nasal carcinomas in dogs. حسب María Dolores Alférez (20129985)

    منشور في 2024
    "…<p dir="ltr">Nasal carcinomas in dogs are locally invasive neoplasms with a low metastatic rate that pose significant treatment challenges due to their location and aggressiveness. …"
  9. 1049

    DataSheet1_Detecting centennial changes in the clarity and colour of the Red and Eastern Mediterranean Seas by retracing the “Pola” expeditions.pdf حسب Jonathan R. Heath (19465312)

    منشور في 2025
    "…The results show a significant greening of both regions investigated as well as a decrease in water clarity. …"
  10. 1050

    DataSheet2_Detecting centennial changes in the clarity and colour of the Red and Eastern Mediterranean Seas by retracing the “Pola” expeditions.csv حسب Jonathan R. Heath (19465312)

    منشور في 2025
    "…The results show a significant greening of both regions investigated as well as a decrease in water clarity. …"
  11. 1051

    Image 1_Global burden trends and future predictions of ischemic heart disease attributable to air pollution in people aged 60 years and older, 1990–2021.jpeg حسب Yuanqin Zhao (4435384)

    منشور في 2025
    "…Projections for 2036 are for a significant increase in IHD cases and global public health policies should be directed towards reducing AP and developing efficient health care infrastructure to address future challenges.…"
  12. 1052

    The Plastic Footprint of the U.S. Agricultural System حسب Katie Malarkey (18020788)

    منشور في 2025
    "…Plastic use in food production is a complex part of this challenge: plastics can increase crop yields, extend growing seasons, and decrease manual labor, but their production, use, and waste leads to environmental and human health impacts. …"
  13. 1053

    Icaritin and lenvatinib treatment for unresectable localized progressive pancreatic cancer: a report of six cases حسب Xiaolong Liu (265696)

    منشور في 2025
    "…<p>Pancreatic cancer is very difficult to detect in its early stages, and its rapid progression and poor prognosis make it a significant therapeutic challenge. Existing treatment modalities, whether standalone or combined, offer limited efficacy, highlighting an urgent need for more effective and less toxic therapeutic strategies.…"
  14. 1054

    Data Sheet 1_Trends in nontraumatic subarachnoid hemorrhage-related mortality among young adult (15–64 years) population in the United States, 1999–2022.docx حسب Olivia Foley (20535083)

    منشور في 2025
    "…Due to the unique challenges that younger adults (aged 15–64 years) may face, it is important to analyze NSAH-related mortality among this age group stratified to determine who is most at risk.…"
  15. 1055

    Image 1_Application of adaptive virtual synchronous generator based on improved active power loop in photovoltaic storage systems.pdf حسب Youzhuo Zheng (20574962)

    منشور في 2025
    "…<p>In the process of integrating distributed energy, photovoltaic (PV) power generation systems encounter issues of intermittency and volatility, posing significant challenges to the stability of the power grid. …"
  16. 1056

    DTG 3TC HIV EPI study.xlsx حسب Anna Esman (17983927)

    منشور في 2024
    "…<p dir="ltr">The persistence of human immunodeficiency virus (HIV) within viral reservoirs poses significant challenges to eradication efforts. Epigenetic alterations, including DNA methylation, are potential factors influencing HIV latency and persistence. …"
  17. 1057

    Table 1_The impact of public participatory environmental regulation on carbon emission intensity: a policy text analysis.docx حسب Jianzu Wu (13935369)

    منشور في 2025
    "…The findings reveal that: (1) public participatory environmental regulation significantly reduces carbon emission intensity; specifically, baseline regression results indicate that a one-unit increase in public participatory environmental regulation intensity leads to a 0.05 unit decrease in carbon emission intensity, significant at the 1% level; (2) mediation analysis demonstrates that public environmental participation serves as a significant intermediary between environmental regulation and carbon emission reduction; (3) heterogeneity analysis indicates that official characteristics significantly moderate policy effectiveness, with regulations implemented by non-local, shorter-tenured, and less-educated officials showing stronger inhibitory effects on carbon emissions compared to their counterparts. …"
  18. 1058

    Data Sheet 1_Effects of cattle manure and sludge vermicompost on nutrient dynamics and yield in strawberry cultivation with distinct continuous cropping histories in a greenhouse.d... حسب Xiaofeng Bai (711688)

    منشور في 2025
    "…<p>Continuous cropping has emerged as a significant challenge affecting yield and quality in greenhouse strawberries, particularly as the cultivation of strawberries as a protected crop continues to increase. …"
  19. 1059

    Table 1_Nutritionally adequate, healthy, and climate-friendly diets following the Nordic Nutrition Recommendations 2023: an optimization study for Norway.xlsx حسب Julie Lengle (21356141)

    منشور في 2025
    "…Regardless of degree of environmental impact reduction, diets following NNR2023 guidelines will require significant dietary changes compared to observed intake, including an increase in consumption of fruits, vegetables, and grains, and a strong decrease in consumption of red meat, total meat, and discretionary foods. …"
  20. 1060

    Table 1_Experiences of reintegration, relapse, and readmission: a qualitative study among patients with alcohol use disorder in Uganda.docx حسب Hillary Mugabo Mukula (21811385)

    منشور في 2025
    "…Introduction<p>Alcohol Use Disorder (AUD) is a significant public health concern in Uganda, with many patients experiencing relapses. …"