Table 1_Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations.docx حسب Juan Liu (6492)

"…Introduction<p>The emergence of the wide variety of novel tigecycline resistance tet(X) variants, including tet(X3), tet(X4), tet(X5), and tet(X6), has raised a serious threat to global public health and posed a significant challenge to the clinical treatment of multidrug-resistant bacterial infections.…"

Table 1_Adherence to recombinant human growth hormone therapy in children: influencing factors and clinical implications.xlsx حسب Wenjing Chang (8334480)

"…However, non-adherence remains a significant challenge, affecting treatment efficacy and patient prognosis. …"

Table 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.xlsx حسب Xiaofang Guo (385478)

"…Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. …"

Supplementary file 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.docx حسب Xiaofang Guo (385478)

"…Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. …"

Table 1_Biofilm formation and role of other pathogenic factors in the virulence of Staphylococcus epidermidis clinical isolates.docx حسب María Coronada Fernández-Calderón (21993110)

"…<p>Medical device-associated infections represent a significant healthcare challenge, as sterilization of the biomaterial often necessitates device removal. …"

Table 1_Study on the effect of GCY-12 gene on albendazole sensitivity of Haemonchus contortus by RNA interference.xlsx حسب Xindi Chen (6485522)

"…</p>Results<p>The results showed that the gene expression level decreased significantly after GCY-12 interference, and the sensitivity of H. contortus to albendazole increased.…"

Data Sheet 1_Case Report: Dual immunomodulatory and hematologic benefits of rituximab in refractory anemia of ANCA-associated vasculitis.docx حسب Ningjun Shao (20748705)

"…Despite conventional immunosuppressive therapies, refractory anemia remains a significant challenge, with limited strategies targeting inflammation-driven hepcidin dysregulation.…"

Table 1_Identification of two KPC variants, KPC-204 and KPC-227, in ST11-K64 Klebsiella pneumoniae during prolonged hospitalization of a single patient.docx حسب Shijun Sun (9287651)

"…Introduction<p>Carbapenem-resistant Klebsiella pneumoniae (CRKP) represents a critical global public health challenge due to its significant association with morbidity and mortality. …"

Data Sheet 1_Mechanistic insights into pyrolysis temperature-dependent lead (Pb) stabilization in phytoremediation residue-derived biochar.docx حسب Jin Liu (12833)

"…This study addressed this challenge by pyrolyzing Pb-enriched biomass (BM_Pb) across a temperature range (300 °C–700 °C) to produce Pb-enriched biochar (BC_Pb), evaluating its efficacy for safe residue management. …"

Data Sheet 1_Global, regional, and national burden of interstitial lung disease in middle-aged and older adults from 1990 to 2021 with projections to 2050: a systematic analysis of... حسب Long Chen (315739)

"…Background<p>Interstitial lung disease (ILD) constitutes a significant global health challenge. However, existing epidemiological studies predominantly focus on worldwide and regional distribution patterns, while a substantial knowledge gap persists regarding the epidemiological characteristics of ILD among middle-aged and older adults (50–74 years). …"

Table 1_Spatio-temporal patterns and determinants of persistent catastrophic health expenditure in China: evidence from the China Family Panel Studies.docx حسب Man-ci Zhou (22776350)

"…Background<p>The escalating out-of-pocket medical expenses pose a significant threat to the financial stability of households worldwide. …"

Data Sheet 1_Global, regional, and national time trends in falls and their predictions: an age-period-cohort analysis of the Global Burden of Disease Study 2021.pdf حسب Huan Jiang (1672375)

"…These findings underscore the urgent need for age- and region-specific interventions to address this public health challenge.</p>…"

Table 1_Gut-to-tumor translocation of multidrug-resistant Klebsiella pneumoniae shapes the microbiome and chemoresistance in pancreatic cancer.docx حسب Lei Zhao (144153)

"…Nevertheless, the complexity of gut microbiota composition poses significant challenges in identifying definitive clinical biomarkers for PC.…"

Supplementary Material for: Innovative regenerative treatment with Nanofat injection for hypertensive ischemic leg ulcer: a case report حسب figshare admin karger (2628495)

"…Background: Martorell's ulcer, also known as hypertensive ischemic leg ulcer (HYTILU) or Martorell hypertensive ischemic ulcer, presents significant therapeutic challenges. The regenerative potential of Nanofat, derived from adipose tissue, offers a promising therapeutic option. …"

Coupled dynamic characteristics of the hull and cushioning structure of high-speed water entry vehicle حسب Lei Xu (78676)

"…<p>To mitigate the extreme mechanical challenges posed by peak and intense instantaneous impacts during high-speed water entry, this paper proposes a rigid polyurethane foam (RPUF) filled cushioning structure to absorb impact energy and minimize hull deformation. …"

Data Sheet 1_Age-related white matter alterations in children with neurofibromatosis type 1: a diffusion MRI tractography study.pdf حسب Lisa Bruckert (6680384)

"…Compared to controls, children with NF1 had significantly increased MD and significantly decreased FA in multiple white matter pathways including the anterior thalamic radiation, cingulate, uncinate fasciculus, inferior fronto-occipital fasciculus, arcuate fasciculus, and corticospinal tract. …"

Effects of eucalypt and black wattle biochars from vacuum pyrolysis on sandy soil quality and cauliflower yield حسب S Mncedi (20667558)

"…<p>Woody invasive alien plants (IAPs), including black wattle (<i>Acacia mearnsii</i> De Wild.) and eucalypt species (<i>Eucalyptus camaldulensis</i> Dehnh.), present significant environmental challenges in South Africa. …"

Table 6_How efficient are specialized public health services in China? A data envelopment analysis and geographically weighted regression approach.docx حسب Qian Bai (605328)

"…Background<p>The Chinese public health system is grappling with escalating demands, which stemmed from the challenges of preventing chronic and infectious diseases, as well as the aging population. …"

Table 1_MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.xlsx حسب Kai Sun (140584)

"…The complex pathogenesis and therapeutic resistance of liver hepatocellular carcinoma (LIHC) present significant clinical challenges. This study investigates MFSD12’s potential involvement in LIHC progression.…"

Data Sheet 1_MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.zip حسب Kai Sun (140584)

"…The complex pathogenesis and therapeutic resistance of liver hepatocellular carcinoma (LIHC) present significant clinical challenges. This study investigates MFSD12’s potential involvement in LIHC progression.…"