Showing 1,501 - 1,520 results of 2,040 for search '(( significant decrease decrease ) OR ( significant (challenge OR challenges) decrease ))~', query time: 0.40s Refine Results
  1. 1501

    Supplementary file 1_Collaborative optimal operation control of HVAC systems based on multi-agent.docx by Chen Fu (165356)

    Published 2025
    “…As a consequence, the computing efficiency of optimization algorithms is relatively low, posing challenges for real-time optimal operation control. …”
  2. 1502

    Data Sheet 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf by Mattia Dalle Nogare (22696022)

    Published 2025
    “…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”
  3. 1503

    Data Sheet 1_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.docx by Shirong Ruan (15414081)

    Published 2024
    “…Background<p>Neuropathic pain (NPP) is a multifaceted pain syndrome that occurs as a consequence of physical injury or underlying diseases, with an incidence rate of 7%-10%, NPP poses a significant clinical challenge as current treatment options are ineffective. …”
  4. 1504

    Data_Sheet_1_Cytomegalovirus results in poor graft function via bone marrow-derived endothelial progenitor cells.pdf by Weiran Lv (715679)

    Published 2024
    “…Introduction<p>Poor graft function (PGF), characterized by myelosuppression, represents a significant challenge following allogeneic hematopoietic stem cell transplantation (allo-HSCT) with human cytomegalovirus (HCMV) being established as a risk factor for PGF. …”
  5. 1505

    Video 8_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4 by Shirong Ruan (15414081)

    Published 2024
    “…Background<p>Neuropathic pain (NPP) is a multifaceted pain syndrome that occurs as a consequence of physical injury or underlying diseases, with an incidence rate of 7%-10%, NPP poses a significant clinical challenge as current treatment options are ineffective. …”
  6. 1506

    Data Sheet 7_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

    Published 2025
    “…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”
  7. 1507

    Table 1_Exploring the antibacterial and anti-biofilm properties of Diacerein against methicillin-resistant Staphylococcus aureus.docx by Yingying Sun (568696)

    Published 2025
    “…Background<p>Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant clinical challenge due to its multidrug resistance. …”
  8. 1508

    Data_Sheet_2_Cytomegalovirus results in poor graft function via bone marrow-derived endothelial progenitor cells.pdf by Weiran Lv (715679)

    Published 2024
    “…Introduction<p>Poor graft function (PGF), characterized by myelosuppression, represents a significant challenge following allogeneic hematopoietic stem cell transplantation (allo-HSCT) with human cytomegalovirus (HCMV) being established as a risk factor for PGF. …”
  9. 1509

    Image 3_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.tif by Shirong Ruan (15414081)

    Published 2024
    “…Background<p>Neuropathic pain (NPP) is a multifaceted pain syndrome that occurs as a consequence of physical injury or underlying diseases, with an incidence rate of 7%-10%, NPP poses a significant clinical challenge as current treatment options are ineffective. …”
  10. 1510

    Image 1_Exploring the antibacterial and anti-biofilm properties of Diacerein against methicillin-resistant Staphylococcus aureus.tif by Yingying Sun (568696)

    Published 2025
    “…Background<p>Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant clinical challenge due to its multidrug resistance. …”
  11. 1511

    Data Sheet 3_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

    Published 2025
    “…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”
  12. 1512

    Image_1_Cytomegalovirus results in poor graft function via bone marrow-derived endothelial progenitor cells.PNG by Weiran Lv (715679)

    Published 2024
    “…Introduction<p>Poor graft function (PGF), characterized by myelosuppression, represents a significant challenge following allogeneic hematopoietic stem cell transplantation (allo-HSCT) with human cytomegalovirus (HCMV) being established as a risk factor for PGF. …”
  13. 1513

    Data Sheet 4_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

    Published 2025
    “…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”
  14. 1514

    Data Sheet 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf by Mattia Dalle Nogare (22696022)

    Published 2025
    “…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”
  15. 1515

    Table 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx by Mattia Dalle Nogare (22696022)

    Published 2025
    “…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”
  16. 1516

    Image 4_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.tif by Shirong Ruan (15414081)

    Published 2024
    “…Background<p>Neuropathic pain (NPP) is a multifaceted pain syndrome that occurs as a consequence of physical injury or underlying diseases, with an incidence rate of 7%-10%, NPP poses a significant clinical challenge as current treatment options are ineffective. …”
  17. 1517

    Video 7_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4 by Shirong Ruan (15414081)

    Published 2024
    “…Background<p>Neuropathic pain (NPP) is a multifaceted pain syndrome that occurs as a consequence of physical injury or underlying diseases, with an incidence rate of 7%-10%, NPP poses a significant clinical challenge as current treatment options are ineffective. …”
  18. 1518

    Data Sheet 1_Decoding population PM2.5 exposure in China: interplay of emissions, meteorology, and inequality (2013–2020).docx by Sujing Li (564578)

    Published 2025
    “…Meteorological conditions have generally mitigated PM<sub>2.5</sub> exposure, with the most significant dispersion effect in 2018. Notably, meteorology’s role in mitigating inequality in occupational exposure significantly decreased from 43.7% in 2013 to 4.5% in 2019, while its exacerbating effect on urban–rural inequality, contributing 43.7% in 2010, drastically reduced by 2020, even shifting to a slight alleviating role. …”
  19. 1519

    Image 5_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.tif by Shirong Ruan (15414081)

    Published 2024
    “…Background<p>Neuropathic pain (NPP) is a multifaceted pain syndrome that occurs as a consequence of physical injury or underlying diseases, with an incidence rate of 7%-10%, NPP poses a significant clinical challenge as current treatment options are ineffective. …”
  20. 1520

    Scarless excision of an insertion sequence in the OmpK36 promoter restores meropenem susceptibility in a non-carbapenemase-producing <i>Klebsiella pneumoniae</i> by Yingying Du (5877701)

    Published 2025
    “…<p>Carbapenem-resistant <i>Klebsiella pneumoniae</i> (CRKP) poses a significant global health challenge due to its limited treatment options and high mortality rates. …”