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18781
Table 3_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx
Published 2025“…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”
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18782
Table2_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p...
Published 2024“…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”
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18783
Table 2_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx
Published 2025“…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”
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18784
Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx
Published 2025“…Both the DN rat model and HG-stimulated HK-2 cells exhibited enhanced EMT markers, with significantly increased α-SMA and vimentin expression (p < 0.001), and decreased E-cadherin levels (p < 0.001). …”
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18785
Changes in functional connectivity between NREM and REM – comparison of in vivo experimental and in silico modeling data.
Published 2025“…However, animals that underwent CFC exhibited a significant increase in the number of cell pairs that strengthen functional connectivity (during REM), as compared to baseline (K-S test comparing baseline and CFC <i>p</i> = 6.0102e-126). …”
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18786
<i>mig-21</i> sensitizes adult DTCs to polarizing signals.
Published 2025“…An “extra turn” to “overmigration” defect shift was observed. A robust “extra turn” defect rate of control on <i>vab-3</i> RNAi (n=38/57) decreases with <i>mig-21(u787)</i> on <i>vab-3</i> RNAi (n=24/65), p < 0.01. …”
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18787
Figure 2 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma
Published 2025“…<p>PD-1 blockade is minimally effective in AB12 and AE17O mouse mesothelioma tumors before or after TI. <b>A,</b> In subcutaneous AB12 mouse mesothelioma tumors, TI significantly decreased the median tumor growth time to 400 mm<sup>3</sup> from 7 days compared with 9 days in untreated TC (<i>P</i> = 0.025). …”
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18788
Figure 1 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Published 2025“…<b>F,</b> Distribution of regression coefficients for linear mixed-effects models fit for each of 14,120 genes and each of the variables included in the model, with a total number of genes significantly (FDR < 0.05) associated with a variable highlighted at the top. …”
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18789
Data collected from pregnant women for the analysis of placental anemia, placental malaria, Cytokines and birth anthropometric indices
Published 2025“…Pathologies associated with PM seems to be the effect of a change in immune status from antibody-mediated immune response to cell-mediated immune response resulting into excess inflammation, oxidative stress, apoptosis, and decreased heat shock protein expression [4]. …”
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18790
USUV replicates in STAT1-sufficient peripheral tissues leading to spleen and liver pathology.
Published 2025“…<b>(G)</b> H&E staining of spleen tissue collected from mock or USUV-infected mice with a 200 µm scale bar. Decreased red pulp due to massive immune cell infiltration was observed in Vav-Cre/<i>Stat1</i><sup>fl/fl</sup> and <i>Stat1</i><sup>-/-</sup> mice. …”
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18791
S1 File -
Published 2024“…Body size, body composition, and maturity had a significant, but of moderate power, effect on the selection. …”
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18792
Flowchart of the selection program.
Published 2024“…Body size, body composition, and maturity had a significant, but of moderate power, effect on the selection. …”
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18793
Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer”
Published 2025“…TRIM37 overexpression decreased palbociclib sensitivity, while its knockdown enhanced sensitivity and attenuated the effect of AR on RB1 levels and drug response, establishing TRIM37 as a novel E3 ligase that bound RB1 via its MATH and C-terminal domains.…”
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18794
Digitized maps of vascular plant species distributions in Denmark in the early 20th century
Published 2025“…<p dir="ltr"><b>Historic data are essential for quantifying changes in biodiversity and drivers thereof. A large part of such legacy data are stored undigitized in archives at e.g., natural history museums, and make up significant untapped resources for insights into past biodiversity patterns. …”
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18795
Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc...
Published 2025“…MR analysis demonstrated a statistically significant causal association between TNF and CKD (OR = 1.02, <i>p</i> < 0.05), with positive trends for IL6 and CASP3. …”
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18796
Excel raw data.
Published 2025“…P-values below 0.05 were seen as a sign of a statistically significant difference.…”
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18797
Hippocampal volume changes along the rostrocaudal axis in the COUP-TFI mutant mice.
Published 2025“…<p><b>(A)</b> 3D whole brain imaging of Thy1-YFP expression in the adult control cortex. …”
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18798
SLMO is required for the proper function of PISD.
Published 2024“…<p>(A) Schematic of the genome-wide RNAi screen for factors that prevent the rescue effects of PISD on the ERG defects of <i>pect</i><sup><i>RNAi</i></sup>. …”
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18799
Image 3_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.tif
Published 2025“…In the AF group, the proportions of EF, APF, and LBCs were increased, whereas the proportion of EC was decreased; by contrast, the SR group displayed a higher proportion of EC. …”
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18800
Table 3_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.xlsx
Published 2025“…In the AF group, the proportions of EF, APF, and LBCs were increased, whereas the proportion of EC was decreased; by contrast, the SR group displayed a higher proportion of EC. …”