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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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6341
Table 1_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.docx
Published 2025“…Treatment with psilocybin resulted in a significant dose-dependent increase in positive BOLD signal. …”
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6342
Data Sheet 3_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx
Published 2025“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”
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6343
Table 5_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.xlsx
Published 2025“…Treatment with psilocybin resulted in a significant dose-dependent increase in positive BOLD signal. …”
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6344
Table 2_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.xlsx
Published 2025“…Treatment with psilocybin resulted in a significant dose-dependent increase in positive BOLD signal. …”
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6345
Data Sheet 2_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx
Published 2025“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”
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6346
Table 3_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.xlsx
Published 2025“…Treatment with psilocybin resulted in a significant dose-dependent increase in positive BOLD signal. …”
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6347
Image 1_Global, regional, and national burden of nutritional deficiencies spanning from 1990 to 2021, with a focus on the impacts observed during the COVID-19 pandemic.tif
Published 2025“…</p>Conclusions<p>Despite a decline in the global burden of nutritional deficiencies over time, significant disparities related to gender, region, and age persist. …”
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6348
The raw data of the paper with the title of " The Protective Effect of Schisandrin C against Methicillin-Resistant Staphylococcus aureus - Induced Otitis Media "
Published 2025“…<p dir="ltr"><a href="" target="_blank">Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) is a significant pathogen in </a><a href="" target="_blank">otitis media</a> (OM), including acute otitis media (AOM) and chronic suppurative otitis media (CSOM), presenting considerable therapeutic challenges due to its biofilm formation, host immune evasion and promotion of persistent inflammation. …”
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6349
Data Sheet 1_Enhancing spelling competence for English as a foreign language young learners through digital escape rooms.docx
Published 2024“…<p>This study examines the efficacy of using a digital gamed platform in acquiring phoneme-grapheme correspondences of closed syllables with short vowels. …”
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6350
Data Sheet 2_Enhancing spelling competence for English as a foreign language young learners through digital escape rooms.docx
Published 2024“…<p>This study examines the efficacy of using a digital gamed platform in acquiring phoneme-grapheme correspondences of closed syllables with short vowels. …”
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6351
Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf
Published 2025“…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …”
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6352
Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx
Published 2025“…</p>Results<p>IGFBP5 was significantly downregulated after PM exposure. Functional investigations demonstrated that IGFBP5 downregulation exacerbated PM-induced oxidative damage, as evidenced by elevated levels of reactive oxygen species (ROS) and malondialdehyde, as well as decreased levels of superoxide dismutase 2 (SOD2). …”
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6353
Systemic injection of TSA reduces hearing loss in <i>Col4a3</i> KO mice.
Published 2025“…(C) The tone burst results showed a significant decrease at 8, 16, 24, and 32 kHz in TSA-treated <i>Col4a3</i> KO mice at 6–7 weeks. …”
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6354
Table 1_Demethylase FTO mediates m6A modification of ENST00000619282 to promote apoptosis escape in rheumatoid arthritis and the intervention effect of Xinfeng Capsule.docx
Published 2025“…Introduction<p>The pathological mechanisms of rheumatoid arthritis (RA) are closely associated with the apoptosis escape of fibroblast-like synoviocytes (FLS). The m6A modification of long non-coding RNAs (lncRNAs) plays a critical regulatory role in RA pathogenesis. …”
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6355
Supplementary file 1_Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut micro...
Published 2025“…Gut microbiota analysis revealed a significant increase in the abundance of Turicibacter, while a reduction of Ruminococcus. …”
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6356
S1 Raw images -
Published 2025“…The TSA-treated group exhibited a reduction in the levels of oxidative stress markers 4-Hydroxynonenal and 3-Nitrotyrosine, along with a decrease in inflammatory cytokines, in both the mouse cochlea and in vitro HEI-OC1 (House Ear Institute-Organ of Corti 1) cell and HEK (Human Embryonic Kidney)293T cells. …”
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6357
Data Sheet 1_Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis.doc...
Published 2025“…The mean difference (MD) or standard mean difference (SMD) with 95% confidence intervals (CIs) were used to evaluate the effect of Tan ⅡA on cognitive function, neuropathology, neuroinflammation, oxidative stress, apoptosis, and neural/synaptic plasticity, with P < 0.05 considered a significant difference. …”
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6358
The clinical characteristic of patients.
Published 2025“…Our subgroup analysis also found a significant relationship between the rate and medical costs.…”
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6359
The results of threshold effect analysis.
Published 2025“…Our subgroup analysis also found a significant relationship between the rate and medical costs.…”
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6360