Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α₁‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents by Chaoquan Tian (21009122)

“…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC₅₀: 4.57 vs 7.22 μM), but its selectivity over α₁-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α_1A-, α_1B-, and α_1D-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …”

Image 1_Dietary acid load on the Mediterranean and a vegan diet: a secondary analysis of a randomized, cross-over trial.jpeg by Hana Kahleova (618836)

“…</p>Conclusion<p>These findings suggest that, compared with the Mediterranean diet, dietary acid load decreased significantly on the low-fat vegan diet and was associated with weight loss. …”

Table 1_Dietary acid load on the Mediterranean and a vegan diet: a secondary analysis of a randomized, cross-over trial.docx by Hana Kahleova (618836)

“…</p>Conclusion<p>These findings suggest that, compared with the Mediterranean diet, dietary acid load decreased significantly on the low-fat vegan diet and was associated with weight loss. …”

Supporting datasets for all figures. by Matthew Drill (22258391)

“…Inhibition of P2X7R with small molecule antagonist AZ10606120, for 72 hours significantly decreased U251 cell number (p < 0.0001), and significantly increased tumour cell death, as evidenced by increased LDH release (p < 0.001). …”

The BAPC model of ASDR. by Chao Zhang (51048)

“…</p><p>Results</p><p>In 2021, the ASDR for HICH was 22.641 per 100,000 people, reflecting a 31.418% decrease from 1990. Similarly, the age-standardized DALYs rate was 521.085 per 100,000 people, marking a 32.163% reduction since 1990. …”

Thousands of chromatin regions show changes in accessibility in response to TOP2i treatment. by E. Renee Matthews (18071587)

Image 1_Plant-based dietary index on the Mediterranean and a vegan diet: a secondary analysis of a randomized, cross-over trial.jpeg by Hana Kahleova (618836)

“…</p>Methods<p>In a cross-over trial, 62 overweight adults followed a Mediterranean and a low-fat vegan diet for 16 weeks in random order, separated by a 4-week washout. …”

qorA associated data by fengning chen (20930834)

“…Transcriptomic and metabolic analyses indicated that the Δ<i>qorA</i> strain underwent a significant metabolic shift to cope with the redox imbalance. …”

Case fatality ratio (%) by year for the 2007–2018 period. by Benjamín Madariaga (18927913)

Fig 1 - by Seung-Jae Kim (6167222)

Data Set. by Gozde Ibili (20715538)

“…The results revealed that maladaptive perfectionism significantly mediated the relationship between mindfulness and procrastination -indicating that dispositional mindfulness has a significant indirect effect on procrastination via decreased levels of maladaptive perfectionism. …”

Conceptual Framework. by Gozde Ibili (20715538)

“…The results revealed that maladaptive perfectionism significantly mediated the relationship between mindfulness and procrastination -indicating that dispositional mindfulness has a significant indirect effect on procrastination via decreased levels of maladaptive perfectionism. …”

Smart spot and smart triage platform. by Rebecca Goertzen (22008461)

“…The inpatient mortality rate decreased from 5.1% in August 2018 to 2.6% in October 2023, with a significant increase in the number of cases with comparable illness severity.…”

HICH patient demographics during QI intervention. by Rebecca Goertzen (22008461)

“…The inpatient mortality rate decreased from 5.1% in August 2018 to 2.6% in October 2023, with a significant increase in the number of cases with comparable illness severity.…”

One-Step Coaxial Electrospinning of PS/BTO@PVDF Core–Shell Nanofibers for Double-Layered TENGs with Ferroelectric-Enhanced Charge Storage Layer by Junseo Gu (20666925)

“…In this study, polystyrene (PS)/BaTiO₃ (BTO)@polyvinylidene fluoride (PVDF) core–shell nanofibers (NFs) were developed through a one-step coaxial electrospinning process, simplifying fabrication while significantly increasing the energy conversion efficiency of the TENG. …”

One-Step Coaxial Electrospinning of PS/BTO@PVDF Core–Shell Nanofibers for Double-Layered TENGs with Ferroelectric-Enhanced Charge Storage Layer by Junseo Gu (20666925)

“…In this study, polystyrene (PS)/BaTiO₃ (BTO)@polyvinylidene fluoride (PVDF) core–shell nanofibers (NFs) were developed through a one-step coaxial electrospinning process, simplifying fabrication while significantly increasing the energy conversion efficiency of the TENG. …”

Transcriptomics-Driven Discovery of New Meroterpenoid Rhynchospenes Involved in the Virulence of the Barley Pathogen <i>Rhynchosporium commune</i> by Reynaldi Darma (20713741)

“…<i>Rhynchosporium commune</i>, the causal agent of barley scald disease, poses a major threat to global barley production. Despite its significant impact, the molecular mechanisms underlying <i>R. commune</i>’s infection process remain largely unexplored. …”

Temporal changes in the extraction socket. by Kohei Ijichi (21656230)

Rat partial phase response curve obtained from entrainment protocol. by Xian Chen (107385)

Sample characteristics. by Debbie Huang (382062)

“…The proportion of days passive data were collected was consistent over time for both groups; the clinical interview and active survey completion decreased over the study course. Results of this study suggest digital phenotyping has significant potential as a method of long-term mental health monitoring in adolescents. …”