Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX by Luyang Su (20411552)

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ², 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ², 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ², 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ², 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ², 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ², 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.…”

Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX by Luyang Su (20411552)

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ², 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ², 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ², 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ², 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ², 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ², 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.…”

AgTL2 embryos have altered lipids, metabolites, and transcriptional profiles during development. by Maurice A. Itoe (9930475)

“…(C) Heatmap of metabolites analyzed by LC-MS showing levels of the 60 most highly dysregulated metabolites in AgTL2 embryos compared to controls throughout development (values of <i>t</i> test statistic, range: blue to red = significant decrease to increase) (3 biological replicates represented by triplicate columns at each time point). …”

Modulation of renal inflammation and tubular injury by calcitriol in patients with early diabetic kidney disease: a randomized controlled trial by Pringgodigdo Nugroho (15460802)

“…Although UACR decreased more in the calcitriol group, the difference was not statistically significant (<i>p</i> = 0.099). …”

Supplementary Material for: Association of MTHFR gene with type 2 diabetes mellitus: A case-control study and meta-analysis by figshare admin karger (2628495)

“…In case-control study at the A1298C(rs1801131), there was no significant association in all genetic models after adjusting for age, gender, and BMI. …”

Data Sheet 1_Efficacy of Schisandra chinensis in liver injury: a systematic review and preclinical meta-analysis.docx by Bo-Hao Huang (18608359)

“…Schisandra chinensis, a traditional Chinese medicinal herb with a history of use spanning over 2,000 years, exhibits significant hepatoprotective, antioxidant, anti-inflammatory, and anti-apoptotic effects. …”

Supplementary Material for: The risk of cardiovascular disease following aromatase inhibitor therapy for breast cancer in postmenopausal women: a systematic review and meta-analysi... by figshare admin karger (2628495)

“…However, there was a significant decrease in the risk of myocardial infarction (RR 0.77, 95% CI: 0.65-0.90, p<0.05) in the AI group when compared to no hormonal treatment. …”

Table 1_Clinical performance of Hedia Diabetes Assistant bolus calculator for diabetes management: a real-world retrospective cohort study.docx by Kenney Fehrenkamp Pedersen (20944706)

“…After 12 weeks, LBGI significantly improved from 0.73 to 0.61 (17% decrease, P < 0.001) with no significant changes in HBGI, and eA1c. …”

Image 2_Hemoglobin glycation index and all-cause mortality in adults: insights from a decade-long prospective cohort study.tif by Yue-Yang Zhang (14258160)

“…</p>Core tip<p>The aim of this study was to assess the association of Hemoglobin Glycation Index(HGI) with all-cause mortality in non-type 2 diabetic patients based on a 10-year cohort study from China. After COX regression, restricted cubic spline analysis, and subgroup analyses, it was found that a significant increase or decrease in HGI adversely affected long-term survival.…”

Image 1_Hemoglobin glycation index and all-cause mortality in adults: insights from a decade-long prospective cohort study.tif by Yue-Yang Zhang (14258160)

“…</p>Core tip<p>The aim of this study was to assess the association of Hemoglobin Glycation Index(HGI) with all-cause mortality in non-type 2 diabetic patients based on a 10-year cohort study from China. After COX regression, restricted cubic spline analysis, and subgroup analyses, it was found that a significant increase or decrease in HGI adversely affected long-term survival.…”

Image 2_Enhanced cognitive control following neurofeedback therapy in chronic treatment-resistant PTSD among refugees: a feasibility study.tiff by Mirjana Askovic (6562304)

“…Post-treatment, clients were categorised into Responders and Non-Responders, with responders defined as those achieving a clinically significant reduction in PTSD symptoms (≥0.5-point decrease on the HTQ).…”

Image 1_Enhanced cognitive control following neurofeedback therapy in chronic treatment-resistant PTSD among refugees: a feasibility study.tiff by Mirjana Askovic (6562304)

“…Post-treatment, clients were categorised into Responders and Non-Responders, with responders defined as those achieving a clinically significant reduction in PTSD symptoms (≥0.5-point decrease on the HTQ).…”

Table 1_Enhanced cognitive control following neurofeedback therapy in chronic treatment-resistant PTSD among refugees: a feasibility study.pdf by Mirjana Askovic (6562304)

“…Post-treatment, clients were categorised into Responders and Non-Responders, with responders defined as those achieving a clinically significant reduction in PTSD symptoms (≥0.5-point decrease on the HTQ).…”

Table 1_Trend of electroconvulsive therapy use and its relationships with clinical characteristics from a large psychiatric center in China.doc by Wei Li (7081)

“…</p>Methods<p>A total of 22,120 inpatients, aged 18–59 years, admitted during the period 2015–2020 to a large grade-A tertiary psychiatric center in Beijing were enrolled in this retrospective study. …”

Table 1_Spatial stratified heterogeneity of mumps incidence in China: a Geodetector-based analysis of driving factors.xlsx by Ke Hu (84619)

“…</p>Results<p>The findings revealed a distinct west-to-east decreasing trend of mumps incidence in China, demonstrating significant spatial autocorrelation primarily manifested as high-high clustering in western areas and low-low clustering in eastern regions. …”

Blood chemistry test results. by Maria A. Colombatti Olivieri (21362615)

“…Red and blue dashed line shows the limit of a significant increase or decrease in the value of the analyte in blood. …”

Data Sheet 1_Nonlinear responses of ecosystem carbon fluxes to precipitation change in a semiarid grassland.doc by Hua Chai (280388)

“…<p>Carbon (C) fluxes in semiarid grasslands subject to precipitation variability play a critical role in the terrestrial C cycle. However, how ecosystem C fluxes respond to variability in precipitation (both decreases and increases precipitation along a gradient) remains unclear. …”

Table 1_Molecular epidemiological characteristics of pertussis in a pediatric hospital in Jinan City, China, 2022 to 2024.docx by Miao Liu (148274)

“…Annual BP positivity rates showed a significant increase from 2022 to 2024 (14.56, 3.26, and 32.24%, respectively; χ² = 2698.353, p < 0.001). …”

Table 1_Case Report: Generalized anxiety disorder and hypertension: a bidirectional loop unraveled by integrated management.docx by Junming Chen (3603422)

“…Background<p>Generalized anxiety disorder (GAD) and hypertension (HTN) exhibit a clinically significant bidirectional relationship characterized by neuroendocrine dysregulation and autonomic dysfunction. …”

Analysis of errors of the AI model on accuracy and decision times for different tasks during the retrospective reader study. (a) by Kerol Djoumessi (21349992)