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significant advancements » significant advancement (Expand Search), significant advantages (Expand Search), significant improvements (Expand Search)
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significant advancements » significant advancement (Expand Search), significant advantages (Expand Search), significant improvements (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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641
Table 1_A population-based registry study on psoriasis-associated burden of disease in Finland.docx
Published 2025“…The number of all-cause secondary healthcare outpatient contacts per year (11.1 vs. 7.4 per patient; p < 0.001) and disease-related inpatient days (0.46 vs. 0.16 per patient; p < 0.001) was lower 1 year after the initiation of biologic treatment in the first biological cohort compared to the time before biologic treatment. The decrease in the disease-related any-type contact cost per year for the first biological cohort was significant, from €2,098 (95% CI: 1,975, 2,221) to €1,094 (95% CI: 1,012, 1,176; p < 0.001). …”
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642
Data Sheet 1_Global trends and future predictions of gastrointestinal ulcers in youth.pdf
Published 2025“…While the raw numbers of cases and mortality have risen, age-standardized rates have decreased, reflecting advancements in healthcare strategies. …”
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643
Table 1_Efficiency analysis of primary health care resources: DEA and Tobit regression evidence from village clinics in Jiangsu Province.docx
Published 2025“…From 2015 to 2022, the average Malmquist Productivity Index was 0.96, with a significant decline of 11.6% in 2021–2022, primarily due to a 6.8% decrease in technological change. …”
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644
Table 2_Efficiency analysis of primary health care resources: DEA and Tobit regression evidence from village clinics in Jiangsu Province.docx
Published 2025“…From 2015 to 2022, the average Malmquist Productivity Index was 0.96, with a significant decline of 11.6% in 2021–2022, primarily due to a 6.8% decrease in technological change. …”
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645
Table 3_Efficiency analysis of primary health care resources: DEA and Tobit regression evidence from village clinics in Jiangsu Province.docx
Published 2025“…From 2015 to 2022, the average Malmquist Productivity Index was 0.96, with a significant decline of 11.6% in 2021–2022, primarily due to a 6.8% decrease in technological change. …”
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646
Data Sheet 1_PANoptosis-related gene clusters and prognostic risk model in clear cell renal cell carcinoma.docx
Published 2025“…Background<p>Despite advancements in targeted therapies, the prognosis for clear cell renal cell carcinoma (ccRCC) remains poor, particularly for metastatic cases. …”
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647
Data_Sheet_2_Antibacterial effects of human mesenchymal stem cells and their derivatives: a systematic review.PDF
Published 2024“…Introduction<p>The growing problem of antimicrobial resistance (AMR) poses a significant challenge to public health; This is partly due to the lack of advancements in the development of novel antibiotics and the pressing need for alternative treatment options. …”
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648
Data Sheet 1_Acupuncture might enhance word recognition scores in a patient with hearing loss: a case report and literature review.pdf
Published 2025“…Sensorineural hearing loss not only causes an increase in the pure tone audiometry of patients, but also may lead to a decrease in word recognition scores. Although contemporary medical advancements like cochlear hearing devices and auditory aids provide some assistance to individuals with hearing loss, many patients still seek more natural and non-invasive treatment options.…”
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649
Data_Sheet_1_Antibacterial effects of human mesenchymal stem cells and their derivatives: a systematic review.PDF
Published 2024“…Introduction<p>The growing problem of antimicrobial resistance (AMR) poses a significant challenge to public health; This is partly due to the lack of advancements in the development of novel antibiotics and the pressing need for alternative treatment options. …”
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650
Table 1_Temporal trends of cervical cancer demographics: a CDC WONDER database study.docx
Published 2025“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. Black or African American patients experienced the highest AAMR across races but maintained a decrease in mortality rate over the study period [AAPC of -2.670* (95% CI -2.931 to -2.356)]. …”
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651
Image 4_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png
Published 2025“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. Black or African American patients experienced the highest AAMR across races but maintained a decrease in mortality rate over the study period [AAPC of -2.670* (95% CI -2.931 to -2.356)]. …”
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652
Image 2_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png
Published 2025“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. Black or African American patients experienced the highest AAMR across races but maintained a decrease in mortality rate over the study period [AAPC of -2.670* (95% CI -2.931 to -2.356)]. …”
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653
Image 3_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png
Published 2025“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. Black or African American patients experienced the highest AAMR across races but maintained a decrease in mortality rate over the study period [AAPC of -2.670* (95% CI -2.931 to -2.356)]. …”
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654
Image 5_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png
Published 2025“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. Black or African American patients experienced the highest AAMR across races but maintained a decrease in mortality rate over the study period [AAPC of -2.670* (95% CI -2.931 to -2.356)]. …”
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655
Image 1_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png
Published 2025“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. Black or African American patients experienced the highest AAMR across races but maintained a decrease in mortality rate over the study period [AAPC of -2.670* (95% CI -2.931 to -2.356)]. …”
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656
Image 1_Markers of immunosenescence in CMV seropositive healthy elderly adults.tif
Published 2025“…<p>A significant increase in life expectancy has accompanied the growth of the world’s population. …”
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657
DataSheet1_Glioma-associated oncogene homolog 1 in breast invasive carcinoma: a comprehensive bioinformatic analysis and experimental validation.docx
Published 2024“…Background<p>Breast cancer, despite significant advancements in treatment, remains a major cause of cancer-related deaths among women. …”
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658
Global, regional and national burden of colorectal cancer and its risk factors, 1990-2021: a systematic analysis for the GBD 2021
Published 2025“…<p dir="ltr"><b>Importance: </b>Colorectal cancer (CRC) constitutes a significant segment of the global cancer burden, thereby warranting an in-depth epidemiological appraisal to inform strategic public health interventions and resource allocation. …”
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659
Experimental investigation on treatment of high-water-content dredged slurry with vacuum preloading-airbag pressurization
Published 2025“…In addition, the microstructural analysis reveals that the VP-AP method can effectively mitigate the decrease in drainage efficiency caused by the clogging of the PVD and improve the structure of the soils, allowing a significant increase in the mechanical properties of the soils. …”
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660
Image 1_Age-related obesity and inflammaging in cats.pdf
Published 2025“…Severely obese cats show excessive visceral fat accumulation, significantly increased triglyceride, free fatty acids, and TNF-α plasma concentrations as pro-inflammatory markers, and a significant decrease in adiponectin. …”