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advances decrease » advanced disease (Expand Search), advanced defense (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant advances » significant advantages (Expand Search), significantly advanced (Expand Search), significant advancements (Expand Search)
advances decrease » advanced disease (Expand Search), advanced defense (Expand Search)
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641
Supplementary file 1_Mortality trends in extremely premature neonates: insights from the CDC WONDER database from 1999 to 2023.docx
Published 2025“…</p>Results<p>Extreme immaturity resulted in 92,917 deaths among neonates in their first year of life from 1999 to 2023. Overall CMR significantly decreased across the study period [AAPC −1.14* 95% CI (−1.45, −0.83)], with both female and male neonates experiencing a significant decrease in CMR [AAPC −1.32* 95% CI [−1.63, −1.06] and AAPC −1.10* 95% CI [−1.57, −0.68] respectively]. …”
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642
Table 1_A population-based registry study on psoriasis-associated burden of disease in Finland.docx
Published 2025“…The number of all-cause secondary healthcare outpatient contacts per year (11.1 vs. 7.4 per patient; p < 0.001) and disease-related inpatient days (0.46 vs. 0.16 per patient; p < 0.001) was lower 1 year after the initiation of biologic treatment in the first biological cohort compared to the time before biologic treatment. The decrease in the disease-related any-type contact cost per year for the first biological cohort was significant, from €2,098 (95% CI: 1,975, 2,221) to €1,094 (95% CI: 1,012, 1,176; p < 0.001). …”
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643
Table 1_Global trends and stratified analysis of aortic aneurysm mortality: insights from the GBD 2021 study.docx
Published 2025“…The estimated annual percentage change in ASDR was −0.81 (95% CI: −0.95 to −0.66), and the average annual percentage change was −0.99 (95% CI: −1.07 to −0.90). Significant regional differences were observed, with high SDI regions experiencing a notable decrease in mortality rates, while low and low-middle SDI regions saw a substantial increase in deaths and an upward trend in mortality rates. …”
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644
Distribution patterns of Platycodon grandiflorus from the last inter-glacial period to the future by ecological niche modeling
Published 2025“…<p dir="ltr">Global climate change may represent a significant threat to the distribution and quality of medicinal plants, altering cultivation areas and compromising the quality of medical materials. …”
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645
Data Sheet 1_Global trends and future predictions of gastrointestinal ulcers in youth.pdf
Published 2025“…While the raw numbers of cases and mortality have risen, age-standardized rates have decreased, reflecting advancements in healthcare strategies. …”
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646
Experimental investigation on treatment of high-water-content dredged slurry with vacuum preloading-airbag pressurization
Published 2025“…In addition, the microstructural analysis reveals that the VP-AP method can effectively mitigate the decrease in drainage efficiency caused by the clogging of the PVD and improve the structure of the soils, allowing a significant increase in the mechanical properties of the soils. …”
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647
Image 1_Age-related obesity and inflammaging in cats.pdf
Published 2025“…Severely obese cats show excessive visceral fat accumulation, significantly increased triglyceride, free fatty acids, and TNF-α plasma concentrations as pro-inflammatory markers, and a significant decrease in adiponectin. …”
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648
Image 1_Global burden trends and future predictions of ischemic heart disease attributable to air pollution in people aged 60 years and older, 1990–2021.jpeg
Published 2025“…Overall, the disease burden in the older adult population remains high, with older age groups experiencing the greatest burden and the most significant decrease in ASRs. Men consistently faced a higher burden than women. …”
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649
Table 2_Cost-effectiveness of the 3E model in diabetes management: a machine learning approach to assess long-term economic impact.docx
Published 2025“…</p>Results<p>The 3E model demonstrated significant cost reductions, with the intervention group achieving a 74.3% decrease in total costs compared to 41.8% in the control group while maintaining the same level of glycemic control. …”
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650
Table 1_Cost-effectiveness of the 3E model in diabetes management: a machine learning approach to assess long-term economic impact.xlsx
Published 2025“…</p>Results<p>The 3E model demonstrated significant cost reductions, with the intervention group achieving a 74.3% decrease in total costs compared to 41.8% in the control group while maintaining the same level of glycemic control. …”
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651
Supplementary file 1_Predicting HIV self-testing intentions among Chinese college students: a dual-model analysis integrating health belief constructs and machine learning prioriti...
Published 2025“…Random forest modeling prioritized these psychological constructs (mean decrease Gini >2.5), identifying male students and arts majors as critical subpopulations requiring targeted intervention.…”
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652
Table 1_Evaluating the global, regional, and national burden of congenital heart disease in infants younger than 1 year: a 1990–2021 systematic analysis for the GBD study 2021.docx...
Published 2025“…By 2021, its mortality rates had decreased to the eighth leading cause of death.</p>Interpretation<p>CHD remains a significant and rapidly escalating global challenge in child health. …”
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653
Table 1_Efficacy of thymosin α1 for sepsis: a systematic review and meta-analysis of randomized controlled trials.docx
Published 2025“…Background<p>Despite advances in understanding sepsis pathophysiology and extensive research, few treatments effectively target its underlying immune dysfunction. …”
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654
Data Sheet 1_Evaluating the global, regional, and national burden of congenital heart disease in infants younger than 1 year: a 1990–2021 systematic analysis for the GBD study 2021...
Published 2025“…By 2021, its mortality rates had decreased to the eighth leading cause of death.</p>Interpretation<p>CHD remains a significant and rapidly escalating global challenge in child health. …”
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655
Data Sheet 2_Evaluating the global, regional, and national burden of congenital heart disease in infants younger than 1 year: a 1990–2021 systematic analysis for the GBD study 2021...
Published 2025“…By 2021, its mortality rates had decreased to the eighth leading cause of death.</p>Interpretation<p>CHD remains a significant and rapidly escalating global challenge in child health. …”
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656
Data_Sheet_1_Exercising educational equity using California’s physical fitness data: a call for more school physical fitness programs, data, and research.docx
Published 2024“…The lack of safe and affordable options for physical activity coupled with the significant decrease in physical activity rates among most American children underscores the need for programs, data, and research on physical fitness in schools, where children spend a significant amount of their time. …”
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657
Table 1_Efficiency analysis of primary health care resources: DEA and Tobit regression evidence from village clinics in Jiangsu Province.docx
Published 2025“…From 2015 to 2022, the average Malmquist Productivity Index was 0.96, with a significant decline of 11.6% in 2021–2022, primarily due to a 6.8% decrease in technological change. …”
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658
Table 2_Efficiency analysis of primary health care resources: DEA and Tobit regression evidence from village clinics in Jiangsu Province.docx
Published 2025“…From 2015 to 2022, the average Malmquist Productivity Index was 0.96, with a significant decline of 11.6% in 2021–2022, primarily due to a 6.8% decrease in technological change. …”
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659
Table 3_Efficiency analysis of primary health care resources: DEA and Tobit regression evidence from village clinics in Jiangsu Province.docx
Published 2025“…From 2015 to 2022, the average Malmquist Productivity Index was 0.96, with a significant decline of 11.6% in 2021–2022, primarily due to a 6.8% decrease in technological change. …”
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660
Video 1_FleXo: a flexible passive exoskeleton optimized for reducing lower back strain in manual handling tasks.mp4
Published 2025“…<p>Musculoskeletal disorders, particularly low back pain, are some of the most common occupational health issues globally, causing significant personal suffering and economic burdens. …”