Image2_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.tif by Yifang He (18126257)

“…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”

Table 1_Prior Trichinella spiralis infection protects against Schistosoma mansoni induced hepatic fibrosis.docx by Asmaa M. El-kady (16502930)

“…Furthermore, pre- infection with T. spiralis markedly reduced S. mansoni- induced hepatic fibrosis, as evidenced by decreased collagen deposition, low expression of α-SMA, and significantly reduced levels of IL-17, IL-1B, IL-6, TGF-B, IL-23, and TNF-α compared to mice infected with S. mansoni only.…”

Table 1_Regulation effect of seed priming on sowing rate of direct seeding of rice under salt stress.pdf by Yicheng Zhang (790286)

“…Our results demonstrated that under T1–T3, the germination rate, α-amylase activity, and soluble sugar and protein contents were significantly increased after priming treatments. The contents of reactive oxygen species (i.e., O₂⁻ and H₂O₂) and malondialdehyde (MDA) were decreased, while the activities of enzymatic antioxidants (i.e., superoxide dismutase, peroxidase, and catalase) and the K⁺/Na⁺ ratio of rice were significantly increased after the above seed priming treatments. …”

Image 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif by Leqing Zhou (20981021)

“…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m², while it decreased by 11.4ml/min/1.73 m² in the RNU group (WMD, 11.81 ml/min/1.73 m²; 95%CI,9.06-14.56; P<0.0001).…”

Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”

Data Sheet 1_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.... by Yuxuan Zhang (1425721)

“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”

Data Sheet 4_Unilateral biportal endoscopic transforaminal lumbar interbody fusion versus minimally invasive transforaminal lumbar interbody fusion for single-level lumbar spondylo... by Yu Zhang (12946)

“…Compared with MIS-TLIF, ULIF demonstrated significantly reduced intraoperative blood loss [WMD = −35.71, 95% CI (−51.80, −19.63), p < 0.01], fewer intraoperative fluoroscopy times [WMD = −1.29, 95% CI (−2.56, −0.02), p < 0.05], lower postoperative drainage volume [WMD = −20.64, 95% CI (−37.13, −4.15), p = 0.01], shorter postoperative ambulation time [WMD = −0.30, 95% CI (−0.42, −0.17), p < 0.01], and decreased hospital stay duration [WMD = −1.50, 95% CI (−2.09, −0.90), p < 0.01]. …”

Table 1_Optimal fertilizer rate and sowing density can improve oat quality, yield and N and P comprehensive efficiency in the Loess Plateau of China.docx by Ruochen Zhang (3434996)

“…The results of correlation analysis revealed significant positive correlations (P< 0.05) of forage yield and CP with nutrients efficiency of oat, but negative correlations with fiber content.…”

Data Sheet 3_Unilateral biportal endoscopic transforaminal lumbar interbody fusion versus minimally invasive transforaminal lumbar interbody fusion for single-level lumbar spondylo... by Yu Zhang (12946)

“…Compared with MIS-TLIF, ULIF demonstrated significantly reduced intraoperative blood loss [WMD = −35.71, 95% CI (−51.80, −19.63), p < 0.01], fewer intraoperative fluoroscopy times [WMD = −1.29, 95% CI (−2.56, −0.02), p < 0.05], lower postoperative drainage volume [WMD = −20.64, 95% CI (−37.13, −4.15), p = 0.01], shorter postoperative ambulation time [WMD = −0.30, 95% CI (−0.42, −0.17), p < 0.01], and decreased hospital stay duration [WMD = −1.50, 95% CI (−2.09, −0.90), p < 0.01]. …”

Supplementary Material for: Minimal Change Disease and Focal Segmental Glomerulosclerosis are associated with good kidney prognosis and Thrombotic Microangiopathy with poor kidney... by Neves P.D.M.M. (20408168)

“…Moreover, the overall distribution of histological profiles showed significant particularities in the analyzed patient cohort, the most important being the higher frequency of TMA cases.…”

Glucose and G-6-P levels modulate HK2-<i>SOX10</i> mRNA association and <i>SOX10</i> mRNA translation. by Ana Luisa Dian (22258504)

“…<p><b>(A)</b> Western blot analysis of HK2 and SOX10 protein level in A375 cells cultured for 24 h with decreasing concentrations of glucose or under glucose starvation, as indicated. …”

Supplementary file 1_Comparative efficacy of femoral neck system vs. cannulated compression screws in young patients with femoral neck fractures: a systematic review and meta-analy... by Weishuai Zhang (22399933)

“…Meta-analysis revealed that, compared to CCS, FNS was associated with a significantly shorted fracture healing time (SMD = 16.30, 95% CI: 3.79–28.82, P < 0.001), decreased intraoperative fluoroscopy usage (WMD) = −8.14, 95% CI: −9.82 to −6.46, P < 0.001), and higher Harris hip scores at the final follow-up (WMD = −3.43, 95% CI: −4.08 to −2.77, P < 0.001). …”

Data_Sheet_1_Association of systemic immune-inflammation index with malnutrition among Chinese hospitalized patients: a nationwide, multicenter, cross-sectional study.docx by Mengyuan Chen (5633153)

“…Both lower and higher SII levels (either continuous or categorical variable) were significantly associated with an increased risk of malnutrition.…”

Table 5_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx by Jianwei Hong (6918776)

“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”

Protein and gene expression levels of p62 and LC3B in miR-7974 mimic-transfected MCF-7 cells. by Stralina Eneh (21213312)

“…<b>(D)</b> The gene expression level of <i>LC3B</i> was decreased and <b>(E)</b> expression level of <i>p62</i> upregulated in miR-7974-treated MCF-7 cells. …”

Data Sheet 1_Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy.pdf by Chun-Fei Wu (22315444)

“…Confocal microscopy demonstrated a significant increase in autophagic flux in Andro-treated SW1353 cells. …”

Table 1_Relationship between advanced lung cancer inflammation index and all-cause and cause-specific mortality among chronic inflammatory airway diseases patients: a population-ba... by Zhuanbo Luo (378365)

“…An elevated ALI was significantly related to a decreased risk of all-cause mortality, as well as mortality from cardiovascular and respiratory diseases among CIAD patients. …”

Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... by Wu Chen (569414)

“…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. Compared to untreated controls, 10-week DBD treatment significantly suppressed lung tumor growth, reduced lesion microvessel density, downregulated HIF-1α and VEGF expression, and ameliorated hematological dysregulation.…”

Supporting data for <b>Drivers, Composition and Potential for Innovative Vector Control Approaches in the mosquito</b> by Lucy Aliette Janet Mirabib Ame De Guilhem De Lataillade (11192853)

“…While most Bacteria and Viruses studied showed correlations with decreased immune gene expression, some, such as Doliuvirus or Siphonobacter, were associated with increased immune gene expression. …”

Data Sheet 1_A longitudinal study on perceived burdensomeness and its influencing factors among older adult hemodialysis patients who migrated with their families in China.pdf by Yun Liu (84346)

“…The family support scores showed a gradually decreasing trend (T1: 10.25 ± 1.91, T2: 9.70 ± 1.84, and T3: 9.13 ± 1.88). …”