Experimental timeline overview. by Leriana Garcia Reis (12646978)

“…Our previous analysis of these mice found HF diet decreased number of pups born, but increased litter growth rate to postnatal (PN) d12. …”

Data Sheet 1_Safety assessment of tolvaptan: real-world adverse event analysis using the FAERS database.docx by Peiyang Cao (10808613)

“…</p>Conclusion<p>While tolvaptan provides therapeutic benefits, it poses a risk of significant adverse reactions. Clinicians should closely monitor the occurrence of events related to hepatobiliary disorders, renal and urinary disorders, metabolic and nutritional disorders, as well as benign, malignant, and indeterminate tumors during its clinical use.…”

Supplementary Material for: Adverse Prognosis in Membranous Nephropathy with PLA2R1 Epitope Spreading: A Prospective Study by figshare admin karger (2628495)

Data extracted from the included studies. by Jesse Hill (19929059)

“…Three studies reported an increase in the proportion of patients admitted after introducing an ADP, one of which was significant while 15 studies reported a significant decrease in admission proportion. …”

Risk of bias assessments for controlled trials. by Jesse Hill (19929059)

“…Three studies reported an increase in the proportion of patients admitted after introducing an ADP, one of which was significant while 15 studies reported a significant decrease in admission proportion. …”

Table 1_The real-world safety of Nivolumab: a pharmacovigilance analysis based on the FDA adverse event reporting system.docx by Yutong Wu (3130584)

“…</p>Conclusions<p>Our large-scale pharmacovigilance study identified significant safety signals associated with nivolumab, including previously unrecognized adverse drug reactions. …”

Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX by Luyang Su (20411552)

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ², 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ², 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ², 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ², 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ², 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ², 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.…”

Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX by Luyang Su (20411552)

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ², 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ², 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ², 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ², 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ², 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ², 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.…”

Drugs causing prostate-specific antigen changes: the food and drug administration adverse event reporting system combined with Mendelian randomization analysis by Wei Zhang (405)

“…</p> <p>Through analysis of the FAERs database, 22 drugs were found to be associated with an increase in PSA, and 14 drugs were associated with a decrease in PSA. MR analysis showed that the use of tamsulosin may lead to an increase in PSA. …”

Annual distribution of IG-ralated AE reports. by Shaozhi Liu (13720340)

“…In the overall population, the most significant signals included blood glucose abnormal (IC025 = 4.86), blood glucose fluctuation (IC025 = 4.69), blood glucose decreased (IC025 = 4.44), hypoglycaemic seizure (IC025 = 4.44) and hypoglycaemic unconsciousness (IC025 = 4.31). …”

Proportion of AEs by SOCs in pregnant women. by Shaozhi Liu (13720340)

“…In the overall population, the most significant signals included blood glucose abnormal (IC025 = 4.86), blood glucose fluctuation (IC025 = 4.69), blood glucose decreased (IC025 = 4.44), hypoglycaemic seizure (IC025 = 4.44) and hypoglycaemic unconsciousness (IC025 = 4.31). …”

Supplementary file 1_Global burden and trends of adverse effects of medical treatment, 1990–2021: an analysis from the global burden of disease study 2021.docx by Keqing Zhang (326894)

“…Background<p>Adverse effects of medical treatment (AEMT) pose a significant global health concern, yet prior studies have mostly focused on specific adverse events or single countries, leaving the long-term global epidemiological patterns insufficiently characterized. …”

Supplementary file 1_Phase angle as a predictor of prolonged length of hospital stay and adverse outcomes in elderly medical inpatients: a retrospective cohort study.docx by Jia Liu (41593)

“…Among these participants, 42 patients (19.3%) experienced composite endpoint events, defined as either one-year readmission or all-cause mortality. Adverse event rates across the PhA tertiles (T1–T3) were 32.9%, 18.6%, and 5.6%, respectively, indicating a significant decrease in event incidence as PhA values increased. …”

Table 1_A real-world disproportionality analysis of ripretinib data mining of the public version of FDA adverse event reporting system.docx by Yingkai Feng (20893169)

“…Notably, the label includes unexpected and significant AEs such as “hepatic neoplasm”, “hair texture abnormal”, “metastases to liver” and “red blood cell count decreased”. …”

Data Set. by Gozde Ibili (20715538)

“…The results revealed that maladaptive perfectionism significantly mediated the relationship between mindfulness and procrastination -indicating that dispositional mindfulness has a significant indirect effect on procrastination via decreased levels of maladaptive perfectionism. …”

Conceptual Framework. by Gozde Ibili (20715538)

“…The results revealed that maladaptive perfectionism significantly mediated the relationship between mindfulness and procrastination -indicating that dispositional mindfulness has a significant indirect effect on procrastination via decreased levels of maladaptive perfectionism. …”

Supplementary file 1_Soluble suppression of tumorigenicity-2 changes during cardiotoxic cancer treatment: a systematic review and meta-analysis.docx by Luca Fazzini (22599380)

Supplementary Material for: The Association of Proteinuria Target Achievement Timing and Stability with Adverse Kidney Outcomes Among Patients with IgA Nephropathy: A Cohort Study by figshare admin karger (2628495)

“…In this study, we aim to evaluate the association of proteinuria target achievement timing and stability with adverse kidney outcomes. Methods: A cohort study was conducted with IgAN patients at Peking University First Hospital. …”

Table 1_Inverse association between triglyceride–glucose index and maximal oxygen uptake in US young and middle-aged population: a cross-sectional study.docx by Bin Zhang (64682)

“…</p>Conclusions<p>In the US young and middle-aged population, the TyG index was significantly adversely associated with VO₂max levels. …”

Data Sheet 1_Adjunctive esketamine in propofol-based sedation for gastrointestinal endoscopy: a systematic review and meta-analysis of randomized trials.docx by Jiazheng Qi (22679312)

“…Combining esketamine with propofol may miti-gate propofol’s adverse effects while enhancing sedation quality. …”