Efficacy of Topical Cyclosporine Combined with Punctal Plugs in Treating Dry Eye Disease and Inflammation by Changming Feng (19810956)

“…</p> <p>In combination therapy group of the clinical trial, the following results were observed: significant improvement in Schirmer I test scores and FBUT compared to the cyclosporine group and punctal plug group, respectively; a decrease in the tear levels of IL-6, IL-1, and MMP-9 compared to the punctal plug group; and a decrease in the tear levels of IL-1α, IL-6, and IL-17 compared to the baseline (all <i>p</i> < 0.05). …”

Processed Data for “Projecting long-term excess risks of major infectious diseases associated with future extreme weather events in Thailand” by Esther Choo (22590272)

“…</p><p dir="ltr">Historically, extreme heat was associated with an increase in all infectious disease incidences except malaria and leptospirosis. …”

Data_Sheet_1_Synergistic co-evolution of rhizosphere bacteria in response to acidification amelioration strategies: impacts on the alleviation of tobacco wilt and underlying mechan... by Zhang Bian-hong (19768686)

“…Nonetheless, all treatments significantly expanded the ecological niche breadth and average variation degree (AVD), enhanced positive interactions and cohesion within the community, and intensified negative interactions involving Ralstonia. …”

Data Sheet 1_Trends in nontraumatic subarachnoid hemorrhage-related mortality among young adult (15–64 years) population in the United States, 1999–2022.docx by Olivia Foley (20535083)

“…NSAH-related mortality decreased in all regions of the US between 1999 and 2022, while individual states demonstrated a variety of trends. …”

The efficacy of topical 8% capsaicin patches for the treatment of postsurgical neuropathic pain: a systematic review by Brandon Goodwin (20328988)

“…The random-effects pooled-analysis denotes an overall Cohen’s d of 1.09 (95% CI: 0.58–1.56; <i>p</i> < 0.001). All studies that investigated neuropathic pain area denote a decrease in pain size, with some denoting a continued reduction with subsequent application.…”

Data Sheet 1_Overarching view of trends and disparities in malignant neoplasm of the ovary between 1999-2023: a comprehensive CDC WONDER database study.docx by Jaikin Patel (22555844)

“…</p>Results<p>Between 1999 and 2023, the AAMR related to malignant neoplasms of the ovary fell from 14.62 in 1999 to 9.52 in 2023. All races analyzed saw a decrease in overall mortality related to malignant neoplasms of the ovary, with the largest decrease being observed in White patients (AAPC: -1.78). …”

Average diet diversity from the Shannon Index (top panel) and average energy density (bottom panel) from frequency of occurrence data before and after 2014. by Ana Lucía Pozas-Franco (20858792)

“…No significant differences were found between mean energy density values between geographic areas before 2014, but there was a statistically significant decrease in the average energy density in the Gulf of California after 2014.…”

GWAS summary statistics for major depressive disorder symptoms (2024) by Mark James Adams (748366)

“…</li></ul><p dir="ltr">Symptoms analysed:</p><ul><li>MDD1: Depressed mood most of the day, nearly every day</li><li>MDD2: Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day</li><li>MDD3: Significant change in weight or appetite</li><li>MDD3a: Significant weight loss or decrease in appetite</li><li>MDD3b: Significant weight gain or increase in appetite</li><li>MDD4: Sleeping too much or not sleeping enough</li><li>MDD4a: Insomnia nearly every day</li><li>MDD4b: Hypersomnia nearly every day</li><li>MDD5: Changes in speed/amount of moving or speaking</li><li>MDD5a: Psychomotor agitation nearly every day</li><li>MDD5b: Psychomotor slowing nearly every day</li><li>MDD6: Fatigue or loss of energy nearly every day</li><li>MDD7: Feelings of worthlessness or excessive or inappropriate guilt</li><li>MDD8: Diminished ability to think or concentrate, or indecisiveness</li><li>MDD9: Recurrent thoughts of death or suicide or a suicide attempt or a specific plan for attempting suicide</li></ul><p></p>…”

Table 1_Association of brain-derived neurotrophic factor levels at different trimesters and new-onset depressive symptom in the third trimester among pregnant women: a longitudinal... by Yue-rong Zhang (21838784)

“…</p>Conclusion<p>Overall, serum BDNF levels in the first, second, and third trimester were significantly associated with decreased PHQ-9 score and reduced risk of prenatal depressive symptoms. …”

Data_Sheet_1_Serum creatinine- and cystatin C-based indices are associated with the risk of subsequent sarcopenia: evidence from the China Health and Retirement Longitudinal Study.... by Xin Ning (1619131)

“…Neither CCR nor SI showed linear or non-linear associations with the risk of subsequent sarcopenia. However, a decrease in pSMI and TBMM was significantly associated with an increased risk of sarcopenia [adjusted per-SD decrease OR, 2.93; 95% CI, 2.09–4.13, p < 0.001; adjusted per-SD decrease OR: 2.38, 95% CI: 1.80–3.16, p < 0.001, respectively].…”

Icaritin and lenvatinib treatment for unresectable localized progressive pancreatic cancer: a report of six cases by Xiaolong Liu (265696)

“…Cases 4 and 5 showed limited relief following a slight decrease in tumor size. In cases 2 and 6, no significant progression of the lesion was observed. …”

Productive indicators comparing harvests 1 and 2. by Zeina El Sebaaly (11478409)

“…The substrate EUC-OS-WB: 400-400-200 had the highest biological efficiency (74.1%) compared to all treatments. Mushroom numbers ranged between 13.0 and 29.5 at harvest 1 (H1) and between 9.5 and 26.5 at harvest 2 (H2), showing a significant decrease in H2 in comparison to H1 in all treatments. …”

Properties of initial substrates. by Zeina El Sebaaly (11478409)

“…The substrate EUC-OS-WB: 400-400-200 had the highest biological efficiency (74.1%) compared to all treatments. Mushroom numbers ranged between 13.0 and 29.5 at harvest 1 (H1) and between 9.5 and 26.5 at harvest 2 (H2), showing a significant decrease in H2 in comparison to H1 in all treatments. …”

It only gets worse … or does it? The relationship between pain duration and psychological pain factors by Cory Alcon (22551286)

“…Participants recruited completed all outcomes via an online survey.</p> <p>Correlation analysis showed that as duration increases, total PCS (<i>r</i> = −.097), PCS – Magnification (<i>r</i> = −.126), and PCS – Helplessness (<i>r</i> = −.088) scores decrease. …”

Inpatient postpartum contraception provision among individuals with opioid use disorder in Maine, 2016–2023 by Catherine Gelsinger (15391022)

“…Annual rate increases per 1000 deliveries were larger over the study period for women with OUD (LAPM: 11.8 [<i>p</i> = 0.02], permanent contraception: 3.96 [<i>p</i> = 0.20], LARC: 6.48 [<i>p</i> = 0.04]) as compared to those for women without OUD (LAPM: 0.46 [<i>p</i> = 0.25], permanent contraception: −0.91 [<i>p</i> = 0.05], LARC: 1.48 [<i>p</i> < 0.01]); all tests of coincidence were significant (<i>p</i> < 0.05).…”

Supplementary Material for: Long-term trends in incidence, attack rates, and early case-fatality of spontaneous intracerebral hemorrhage. Dijon Stroke Registry (1985-2022) by figshare admin karger (2628495)

“…In men, a significant increase in incidence and attack rates was observed from 1985-1991 to 2011-2016, followed by a slight decline. …”

Image 1_Global burden trends and future predictions of ischemic heart disease attributable to air pollution in people aged 60 years and older, 1990–2021.jpeg by Yuanqin Zhao (4435384)

“…Overall, the disease burden in the older adult population remains high, with older age groups experiencing the greatest burden and the most significant decrease in ASRs. Men consistently faced a higher burden than women. …”

Data Sheet 1_An ictogenic marker in the mesial temporal epilepsy and its temporal evolutionary features.pdf by Hongjuan Lu (558920)

“…</p>Results<p>The HYP transients were invariably composed of slow-wave proper, sharp wave and post-slow component among studied patients for all the 93 seizures. During preictal epoch, all of the seizures incorporated present evolutionary manner of type 1 characterized by smooth modification of HYP transients in morphology, including gradual shortening of the inter-transient interval, increase of amplitude and time duration of slow-wave proper and sharp wave, amplitude decrease of the post-slow component, as well as amplitude increases of ripple and fast ripple, and 2/3 seizures showed some more sophisticated transitional manners (type 2) following type 1, including reduction in amplitude with decrease of inter-transient intervals, superimposed or followed by the emergent low amplitude rhythmic activities, or both of them. …”

Polygenic adaptation analysis results for the pairwise and multi-population tests for polygenic adaptation (see Methods). by Olivia A. Gray (20700832)

“…The SNP no. column shows how many SNPS are included in the test at this significance threshold. Significant <i>p</i>-values are highlighted in green (figures for all significant Multi-population tests in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011570#pgen.1011570.s006" target="_blank">S6 Fig</a>). …”

The effect of IFN-β and Vit D on the NF-κB and p-NF-κB protein. by Farzad Nasri (8941850)

“…IFN-β, Vit D, and the co-treatment all decrease p-NF-κB protein expression in comparison with the control, but it was only significant for the co-treatment group <b>(B)</b>. …”