Table 2_Assessment of ovarian dysfunction induced by environmental toxins: a systematic review.xlsx حسب Lu An (3432230)

"…Objective<p>This study systematically assess the potential impact of various environmental pollutants as chemical, airborne, and heavy metal on ovarian function in women, focusing on ovarian reserve such as anti-Müllerian hormone (AMH) and antral follicle count (AFC) as well as hormone levels like follicle-stimulating hormone (FSH) and estradiol (E2). …"

Image 1_HIF1A acts as target of XiHuang Pill in the treatment of papillary thyroid cancer by regulating dedifferentiation.tif حسب Xu-Zhe Yu (21509801)

"…Further, only HIF1A was upregulated in the advanced stage of PTC and significantly correlated with the dedifferentiation (all P < 0.05). …"

Table 2_Dietary retinoic acid improved the growth, lipid metabolism and immune status in Macrobrachium rosenbergii.docx حسب Qin-Cheng Huang (20944886)

"…Compared to the prawns fed 4 mg/kg dietary RA, there was significantly lower lipid deposition in the muscle, hepatopancreas and whole body of prawns fed 296 mg/kg dietary RA. …"

Data Sheet 1_Effects of sodium tanshinone IIA sulfonate injection on pro-inflammatory cytokines, adhesion molecules and chemokines in Chinese patients with atherosclerosis and athe... حسب Fan Xie (562816)

"…</p>Conclusion<p>The use of STS in patients with AS and ASCVD appeared to significantly decrease levels of pro-inflammatory cytokines, adhesion molecules, and chemokines.…"

Table 1_Ten days of supplementation with a standardized Boswellia serrata extract attenuates soreness and accelerates recovery after repeated bouts of downhill running in recreatio... حسب Dawna Salter (18498396)

"…Blood and urine samples collected at baseline, before, and after DHR were analyzed for inflammation-related biomarkers. VAS scores significantly increased while muscle strength decreased from baseline measures after DHR regardless of group assignment (main effect of time p < 0.001). …"

Data Sheet 1_NOP agonist AT-403 promoted sleep in lactic acid-induced acute pain model.pdf حسب Bethany E. Pierce (11063904)

"…Morphine significantly decreased NREM and REM sleep in pain-naïve states and did not improve sleep following lactic acid administration. …"

COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISEASE حسب Janice Keramedjian (19726261)

"…CNS penetrating prodrugs utilizing carriers (Rautio, Laine et al. 2008) such as reduced ascorbic acid (Manfredini, Pavan et al. 2002) for transporting Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are known (Zhao, Qu et al. 2014, Wang, Zhang et al. 2018), as are LAT1 utilizing carriers (Gynther, Laine et al. 2008). …"

The association of piR-651 and piR-823 on metastatic and invasive characteristics of triple negative breast cancer cells حسب Çağrı Öner (3152334)

"…The expressions of Ki-67, HIF-1α, MMP-2, and MMP-9 genes were measured at 48 h, when both cell lines exhibited the most significant effects of inhibition. The optimal time for proliferation of anti-piR-651 and anti-piR-823 transfected MDA-MB-231 cells was determined to be at 48 h, as indicated by decreased motility and invasion assay results (<i>p</i> < 0.001). …"

Cilia disassembly proceeds at a faster rate in CCDC66-depleted cells, which is regulated by the AurkA-HDAC6 axis and rescued by microtubule stabilization. حسب Jovana Deretic (13113617)

"…Cells were fixed at indicated time points with 4% PFA, stained against anti-acetylated-tubulin, ARL13b and DAPI, and imaged with widefield fluorescence microscopy. …"

Table 1_Serum levels of interleukin-17, -18, -22, and -25 in patients with bullous pemphigoid before and after treatment.xlsx حسب Xinyi Hong (8181177)

"…</p>Results<p>The mean serum levels of IL-17, IL-18, IL-22, IL-25, and EOS percentage in BP patients were higher than those in healthy controls (all p < 0.001), and all of these levels decreased after treatment (all p < 0.001). There was no statistically significant difference in the titer of anti-BP180 or anti-BP230 antibodies before and after treatment. …"

Table 2_Serum levels of interleukin-17, -18, -22, and -25 in patients with bullous pemphigoid before and after treatment.xlsx حسب Xinyi Hong (8181177)

"…</p>Results<p>The mean serum levels of IL-17, IL-18, IL-22, IL-25, and EOS percentage in BP patients were higher than those in healthy controls (all p < 0.001), and all of these levels decreased after treatment (all p < 0.001). There was no statistically significant difference in the titer of anti-BP180 or anti-BP230 antibodies before and after treatment. …"

Data Sheet 1_Efficacy of Schisandra chinensis in liver injury: a systematic review and preclinical meta-analysis.docx حسب Bo-Hao Huang (18608359)

"…Schisandra chinensis, a traditional Chinese medicinal herb with a history of use spanning over 2,000 years, exhibits significant hepatoprotective, antioxidant, anti-inflammatory, and anti-apoptotic effects. …"

Modulation of renal inflammation and tubular injury by calcitriol in patients with early diabetic kidney disease: a randomized controlled trial حسب Pringgodigdo Nugroho (15460802)

"…Although UACR decreased more in the calcitriol group, the difference was not statistically significant (<i>p</i> = 0.099). …"

Data Sheet 1_hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways.doc حسب Yan Yu (56143)

"…In addition, SDUY436 demonstrated significant anti-invasive and pro-apoptotic effects in MDA-MB-231 cells. …"

Table 2_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…The primary outcomes included relapse rates, Expanded Disability Status Scale (EDSS) scores, and survival outcomes.</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

Table 4_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…The primary outcomes included relapse rates, Expanded Disability Status Scale (EDSS) scores, and survival outcomes.</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

Table 1_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…The primary outcomes included relapse rates, Expanded Disability Status Scale (EDSS) scores, and survival outcomes.</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…The primary outcomes included relapse rates, Expanded Disability Status Scale (EDSS) scores, and survival outcomes.</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

CuSO₄ data tables. حسب Saima Naz (5066162)

"…A significant (p < 0.05) increase was observed in oxidative stress parameters (ROS, TBARS) whereas the activity of anti-oxidant enzymes (SOD, POD, GSH, CAT) was significantly (p < 0.05) decreased in the gills, brain, liver and kidneys of fish exposed to 0.56 µg/L concentration of CuSO₄. …"

Image 2_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi... حسب Xinchi Shang (11982840)

"…Cr(VI) stress significant increases in H₂O₂ and MDA levels and significant decreases in antioxidant enzyme activity levels (SOD, GSH-Px, and T-AOC) and energy metabolism-related ATPase activity levels (Na⁺K⁺-ATPase, Ca²⁺-ATPase, and Mg²⁺-ATPase). …"