Image 4_Transcutaneous auricular vagus nerve stimulation alleviates inflammation-induced depression by modulating peripheral-central inflammatory cytokines and the NF-κB pathway in... حسب Xingke Song (21372995)

"…</p>Results<p>Behavioral tests demonstrated that LPS-induced rats exhibited significant depressive-like behaviors, including reduced sucrose preference, decreased activity levels in the open field, and restricted exploratory behavior in the elevated plus maze. taVNS intervention significantly alleviated these depressive-like behaviors. …"

Image 1_Transcutaneous auricular vagus nerve stimulation alleviates inflammation-induced depression by modulating peripheral-central inflammatory cytokines and the NF-κB pathway in... حسب Xingke Song (21372995)

"…</p>Results<p>Behavioral tests demonstrated that LPS-induced rats exhibited significant depressive-like behaviors, including reduced sucrose preference, decreased activity levels in the open field, and restricted exploratory behavior in the elevated plus maze. taVNS intervention significantly alleviated these depressive-like behaviors. …"

Table 2_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls حسب Yuanxi Mo (22090130)

"…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …"

Table 5_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls حسب Yuanxi Mo (22090130)

"…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …"

Table 6_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.docx حسب Yuanxi Mo (22090130)

"…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …"

Image 7_Transcutaneous auricular vagus nerve stimulation alleviates inflammation-induced depression by modulating peripheral-central inflammatory cytokines and the NF-κB pathway in... حسب Xingke Song (21372995)

"…</p>Results<p>Behavioral tests demonstrated that LPS-induced rats exhibited significant depressive-like behaviors, including reduced sucrose preference, decreased activity levels in the open field, and restricted exploratory behavior in the elevated plus maze. taVNS intervention significantly alleviated these depressive-like behaviors. …"

Image 3_Transcutaneous auricular vagus nerve stimulation alleviates inflammation-induced depression by modulating peripheral-central inflammatory cytokines and the NF-κB pathway in... حسب Xingke Song (21372995)

"…</p>Results<p>Behavioral tests demonstrated that LPS-induced rats exhibited significant depressive-like behaviors, including reduced sucrose preference, decreased activity levels in the open field, and restricted exploratory behavior in the elevated plus maze. taVNS intervention significantly alleviated these depressive-like behaviors. …"

Table 4_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls حسب Yuanxi Mo (22090130)

"…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …"

Table 2_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.xlsx حسب Amirmohammad Afsharnia (22569827)

"…In conclusion, unlike its acetylated form (NGAM), GAM is a potent anti-biofilm agent that effectively inhibits the biofilm formation of S. aureus Wood 46 and significantly alters the gene expression profile associated with biofilm formation.…"

Image 1_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.jpeg حسب Amirmohammad Afsharnia (22569827)

"…In conclusion, unlike its acetylated form (NGAM), GAM is a potent anti-biofilm agent that effectively inhibits the biofilm formation of S. aureus Wood 46 and significantly alters the gene expression profile associated with biofilm formation.…"

Table 1_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.xlsx حسب Amirmohammad Afsharnia (22569827)

"…In conclusion, unlike its acetylated form (NGAM), GAM is a potent anti-biofilm agent that effectively inhibits the biofilm formation of S. aureus Wood 46 and significantly alters the gene expression profile associated with biofilm formation.…"

Data Sheet 1_Elucidating the mechanism of stigmasterol in acute pancreatitis treatment: insights from network pharmacology and in vitro/in vivo experiments.pdf حسب Xuanlin Zhao (20466980)

"…Stigmasterol, a natural plant sterol found in various herbs and vegetables, exhibits a significant anti-inflammatory, antioxidant, and cholesterol-lowering effects. …"

Data Sheet 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx حسب Yingchao Wu (2870927)

"…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…"

Data Sheet 4_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.pdf حسب Yingchao Wu (2870927)

"…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…"

Data Sheet 3_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx حسب Yingchao Wu (2870927)

"…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…"

Data Sheet 2_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx حسب Yingchao Wu (2870927)

"…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…"

Data Sheet 1_Short-term structured dietary and exercise interventions delay diabetes onset in prediabetic patients: a prospective quasi-experimental study.pdf حسب Zhen Wang (72451)

"…</p>Conclusions<p>Short-term intervention with SAIDEs exhibited significant anti-inflammatory activity and reduced the prevalence of abnormal blood glucose markers. …"

Data Sheet 1_Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3.docx حسب Adina-Gabriela Vasilescu (22236073)

"…Finally, our inhibitor significantly downregulates STAT3-dependent anti-apoptotic genes MCL1 and PIM1.…"

Data Sheet 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.docx حسب Maria Jordan (10265489)

"…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …"

Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx حسب Maria Jordan (10265489)

"…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …"