Video 1_Effect of Fangxia-Dihuang Decoction on doxorubicin-induced cognitive impairment in breast cancer animal model.mp4 حسب Xuan Wang (55634)

"…The results of blood routine and cardiac HE staining showed that compared with the 4T1 group, the serum ALT, AST, CK, LDH, and CKMB in DOX group mice were significantly increased (P<0.05). After FXDH administration, all indicators in mice were decreased, but there was no statistical difference. …"

Supplementary file 1_Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut micro... حسب Liang Wu (131111)

"…</p>Results<p>HSYA significantly inhibited HFD-induced weight gain and alleviated liver inflammation. …"

Data Sheet 1_Linarin alleviates colonic barrier dysfunction induced by enterotoxic Escherichia coli in weaned piglets by regulating the gut microbiota and metabolic pathways.docx حسب Qianqian Zhang (587342)

"…</p>Results<p>Linarin supplementation significantly ameliorated colonic crypt hyperplasia, increased goblet cell numbers, and decreased diarrhea incidence following ETEC infusion. …"

Data Sheet 1_Astaxanthin mitigates doxorubicin-induced cardiotoxicity via inhibiting ferroptosis and autophagy: a study based on bioinformatic analysis and in vivo/vitro experiment... حسب Bowen Yin (11925053)

"…Astaxanthin (ASX), a natural carotenoid pigment, has garnered significant attention for its numerous health benefits. …"

Data Sheet 2_Astaxanthin mitigates doxorubicin-induced cardiotoxicity via inhibiting ferroptosis and autophagy: a study based on bioinformatic analysis and in vivo/vitro experiment... حسب Bowen Yin (11925053)

"…Astaxanthin (ASX), a natural carotenoid pigment, has garnered significant attention for its numerous health benefits. …"

<b>Selective Reduction of Ca</b>^{<strong>2+</strong>}<b>-Independent Phospholipase A</b>_{<strong>2</strong>}<b>b</b><b> (iPLA</b>_{<strong>2</strong>}<b>b... حسب Abdulaziz Almutairi (9584768)

"…</p><p dir="ltr">· Reduction of myeloid-iPLA₂b decreases T1D incidence.</p><p dir="ltr"><br><b>d. …"

Supplementary file 2_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

"…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"

Table 1_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

"…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"

Supplementary file 3_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

"…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"

Supplementary file 1_Restoration of antibiotic associated diarrhea induced gut microbiota disorder by using Dictyophora indusiata water-insoluble polysaccharides in C57BL/6J mice.d... حسب Yong Lai (4104235)

"…Macrofungal polysaccharides are rich in bioactivities and have attracted much attention for their good performance in anti-inflammatory, antioxidant, anti-obesity and anti-tumor properties. …"

Supplementary file 1_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

"…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"

Data Sheet 1_Dehydrozaluzanin C inhibits colon cancer cell proliferation, apoptosis and cycle arrest through peroxisome proliferator-activated receptor γ (PPARγ) activation.pdf حسب Shan-Shan Li (436534)

"…In vivo, DC treatment significantly decreased the weight and volume of xenograft tumor tissues in mice and apoptosis-related protein levels. …"

Glucose and G-6-P levels modulate HK2-<i>SOX10</i> mRNA association and <i>SOX10</i> mRNA translation. حسب Ana Luisa Dian (22258504)

"…<p><b>(A)</b> Western blot analysis of HK2 and SOX10 protein level in A375 cells cultured for 24 h with decreasing concentrations of glucose or under glucose starvation, as indicated. …"

Supplementary file 1_Bibliometrics-guided cyberpharmacology and transcriptomics for multidimensional analysis of the antihepatic fibrosis mechanism of kaempferol.docx حسب Jiali Liu (327739)

"…Pharmacodynamic evaluations, including pathological section analyses, demonstrated that KA effectively mitigated the fibrotic process and decreased collagen deposition. Further corroborated by ELISA experiments, kaempferol exhibited pronounced anti-fibrotic effects, inhibited inflammatory responses, restored liver function indices, and ameliorated the progression of liver fibrosis. …"

Data Sheet 1_Combination of MLo-1508 with sunitinib for the experimental treatment of papillary renal cell carcinoma.docx حسب Ângela Marques-Magalhães (20924831)

"…Importantly, MLo-1508 decreased the sunitinib effective anti-tumoral concentration against ACHN cell viability. …"

Downregulation of ATM1 affects iron-sulfur cluster proteins in <i>Toxoplasma</i> and iron levels in <i>Plasmodium</i>. حسب Deepti Shrivastava (17715780)

"…The number of significantly increased and decreased proteins is given and the NEET protein CDGSH1 is indicated. …"

Table 1_The role of cyano-phycocyanin as a quorum sensing inhibitor to attenuate Pseudomonas aeruginosa virulence.docx حسب Jun Ying (129597)

"…The macrophage and mouse infection model were used to explore the anti-infection ability of C-PC in vitro and in vivo.…"

Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx حسب Hailiang Li (740080)

"…Meanwhile, NADPH+ production and G6PDH enzyme activity significantly decreased. Further study validated that metformin inhibited the cell growth of GBM cell lines through up-regulating PER2 and inhibited SIRT2/G6PD signaling pathway, enhancing radiotherapy(RT) sensitivity. …"

Data Sheet 2_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx حسب Stephanie Dauth (13274397)

"…Background<p>Thyme-ivy syrup has anti-inflammatory activities and exerts beneficial effects on symptom relief and recovery time in patients with acute bronchitis. …"

Data Sheet 1_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx حسب Stephanie Dauth (13274397)

"…Background<p>Thyme-ivy syrup has anti-inflammatory activities and exerts beneficial effects on symptom relief and recovery time in patients with acute bronchitis. …"