Data Sheet 1_Quantitative MRCP metrics as imaging biomarkers to differentiate benign from malignant bile duct obstructions.docx by Kulyada Eurboonyanun (12548926)

“…If detected early, surgical resection carries a 35% 5-year survival rate; this decreases to <11% 1-year survival rate when detected at later stages. …”

Data Sheet 1_An active ingredient from the combination of Corydalis Rhizoma and Paeoniae Radix Alba relieves chronic compression injury-induced pain in rats by ameliorating AR/Mboa... by Ze-Ming Wang (9572399)

“…</p>Results<p>The results demonstrated that YB60 significantly decreased inflammatory cytokine levels both in cellular models and rat serum, while concurrently elevating pain thresholds in CCI rats. …”

Image 1_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif by Kai Liu (159026)

“…We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …”

Data Sheet 1_Effects of aging and valence on emotional response inhibition: conclusions from a novel stop-signal task.pdf by Jill D. Waring (6652103)

“…Aging is associated with decreasing cognitive control and inhibition alongside improvements in emotional control and regulation. …”

Table 1_The role of cyano-phycocyanin as a quorum sensing inhibitor to attenuate Pseudomonas aeruginosa virulence.docx by Jun Ying (129597)

“…In vitro, C-PC reduced the adhesion and invasion of PA2 in RAW264.7 cells, and decreased LDH release and macrophage damage caused by PA2 infection. …”

The prognostic value of the neutrophil-percentage-to-albumin ratio for all-cause and cardiovascular mortality in chronic kidney disease stages G3a to G5: insights from NHANES 2003–... by Jialing Rao (20354623)

“…High levels NPAR exhibited a significantly elevated risk of both all-cause and CVD mortality in the fully adjusted model. …”

Mass spectrometry of Pparα-En4 pulldown proteins. by Tingting Jiang (169999)

“…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”

Data Sheet 1_IgE autoantibodies to nuclear antigens in patients with different connective tissue diseases: re-evaluation and novel findings.docx by Kathrin Kramer (20906207)

“…</p>Results<p>In SLE and SS, IgE anti-SSA/Ro52-, -SSA/Ro60- and -SSB/La-antibodies showed a significantly higher reactivity than in controls. IgE anti-dsDNA-antibodies were present in 66% of SLE patients. …”

Table 11_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx by Linling Du (22827035)

“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”

Description of study characteristics. by Feline de la Court (15194678)

“…Loss of PrEP retention rates were significantly (p < 0.05) lower in studies from Europe, Australia and multiple regions (vs. …”

Image 6_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg by Fushan Lu (20413670)

“…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …”

Table 1_Xinfeng Capsule inhibits oxidative stress via regulating the PPARγ/ Hmgcs2 signaling pathway in lung tissue of adjuvant arthritis rats.docx by Ping-Heng Zhang (21785162)

“…Furthermore, XFC-containing serum suppressed TGF-β1–induced proliferation of lung fibroblasts, promoted PPARγ expression, and significantly decreased the levels of interleukin-6, tumor necrosis factor-α, reactive oxygen species, nicotinamide adenine dinucleotide phosphate oxidase 4, HMGCS2, collagen type I α 1, collagen type III α 1, and α-smooth muscle actin (P < 0.01). …”

Table 1_Association between Life’s Crucial 9 and metabolic dysfunction-associated steatotic liver disease: the mediating role of neutrophil-percentage-to-albumin ratio.docx by Na Zhu (331131)

“…After adjusting for all confounders, LC9 was significantly and negatively associated with both MASLD (OR = 0.59, 95% CI: 0.54–0.64) and hepatic fibrosis (OR = 0.66, 95% CI: 0.45–0.97), with each 10-point increase in the LC9 score decreasing the prevalence by 41% and 34%, respectively. …”

Database of the impact of temperature on development of Aedes aegypti and Aedes albopictus in Cambodia by Bros Doeurk (21163097)

“…During immature stages, development time decreased at higher temperature (35°C), but mortality was increased. …”

Table 1_Global and regional burdens of opioid use disorder from 1990 to 2021, with future forecasts to 2050: a systematic analysis for the global burden of disease study 2021.docx by Juanzhao Cao (22651742)

“…Population growth and epidemiological changes contributed significantly to the increase in the burden of OUD.</p>…”

Table 1_The health burden of disease attributable to low calcium intake: a comprehensive analysis of trends and socioeconomic impacts from 1990 to 2021.docx by Yanping Wang (275956)

“…</p>Conclusion<p>DLC significantly increases the incidence of CRC, while its impact on prostate cancer incidence is relatively minor and shows a negative correlation. …”

Image 1_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif by Marcela Rios-Carlos (22759823)

“…After AFs treatment at 0.1 g/kg, serum IgE levels were normalized to those of control animals. All AFs significantly decreased dermal mast cell and eosinophil counts, as well as epidermal thickening, with greater efficacy observed at lower doses. …”

S1 Raw data - by Dao-Cheng Zhou (20314697)

“…All-cause and CVD mortality gradually decreased with increasing ideal LE8 metrics. LE8 was not significantly associated with cancer mortality. …”

Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf by Mengyuan Dai (9747317)

“…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …”

Image 4_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg by Fushan Lu (20413670)

“…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …”