Showing 381 - 400 results of 1,038 for search '(( significant decrease decrease ) OR ( significant binding decrease ))~', query time: 0.33s Refine Results
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    Multiscale QM/MM Simulations Identify the Roles of Asp239 and 1‑OH···Nucleophile in Transition State Stabilization in Arabidopsis thaliana Cell-Wall Invertase 1 by Wijitra Jitonnom (22410515)

    Published 2025
    “…The 1-OH···nucleophile interaction has been found to provide an important contribution to the transition state stabilization, with a contribution of ∼7 kcal/mol, and affected glycosylation more significantly than deglycosylation. This study provides molecular insights that improve the current understanding of sucrose binding and hydrolysis in members of clan GH-J, which may benefit protein engineering research. …”
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