Reduced expression of MYBPC3 mRNA and cMyBP-C protein in the proband. by Yuanyuan Zhang (101797)

Alternative representation of daunorubicin fluorescence testing of novel inhibitors. by Lauren A. McCormick (20540638)

SAF-A depletion leads to widespread changes in mRNA splicing. by Judith A. Sharp (21519973)

ZIKV infection enriches the HLA Class I pathway in brain tumour cells. by Matt Sherwood (22530221)

Regulation of Rice Grain Weight by Fatty Acid Composition: Unveiling the Mechanistic Roles of <i>OsLIN6</i> by OsARF12 by Haoran Tian (6706925)

“…Compared with the wild type (WT), the <i>OsLIN6</i> knockout mutant exhibited a lower grain weight, an increased C18:1 content, and a decreased C18:2 content. Importantly, OsARF12 was shown to bind to the <i>OsLIN6</i> promoter and activate its expression. …”

Mutation of 1G05 epitope glycan sites impacts avidity. by Zachary T. Berndsen (9230176)

Mechanism of hydrocephalus formation involving inflammation after IVH. by Tong Sun (1564231)

“…<p>Following IVH, blood-related metabolites promote a significant increase in TNF-α levels in CSF. This elevation leads to the binding of TNF-α to its receptor on the CPEs membrane, triggering the activation of IKK in the cytoplasm. …”

Key Resources. by Jeffrey Chin (22538086)

“…Here we explored the role of the host factor, Tax-1 binding protein 1 (Tax1bp1), an autophagy receptor that targets pathogens for degradation through selective autophagy and terminates pro-inflammatory cytokine responses. …”

Tax1bp1-deficiency reduces autophagy flux. by Jeffrey Chin (22538086)

“…Here we explored the role of the host factor, Tax-1 binding protein 1 (Tax1bp1), an autophagy receptor that targets pathogens for degradation through selective autophagy and terminates pro-inflammatory cytokine responses. …”

Data Sheet 1_Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.pdf by Yihong Yang (557831)

“…Meanwhile, HIRI can significantly increase the expression of genes related to liver injury and inflammation, while SEN pretreatment can lead to a concentration-dependent decrease in these genes. …”

Table 1_Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.xls by Yihong Yang (557831)

“…Meanwhile, HIRI can significantly increase the expression of genes related to liver injury and inflammation, while SEN pretreatment can lead to a concentration-dependent decrease in these genes. …”

Table 1_Association between neutrophil percentage-to-albumin ratio and breast cancer in adult women in the US: findings from the NHANES.docx by Huikai Liang (21188720)

“…The significance of traits was assessed using mean decrease accuracy (MDA) and mean decrease impurity (MDI). …”

Data Sheet 1_Understanding mechanistic relationships between IgG titers and Fc effector functions: a computational framework to assess polyfunctionality.docx by Suzanne K. Shoffner-Beck (22253548)

“…Surprisingly, simulated boosting of IgG3 alone had the potential to significantly decrease ADCP (p<0.00001), though it would increase ADCC responses. …”

Data Sheet 2_MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway.pdf by Juan Zhang (48597)

“…In vitro experiments, in which high glucose concentrations were used to stimulate human mesangial cells (HMCs), demonstrated a significant increase in the protein level of high mobility group box 1 (HMGB1) and a marked decrease in miR-216a-5p expression (all P < 0.05). …”

Data Sheet 1_MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway.docx by Juan Zhang (48597)

“…In vitro experiments, in which high glucose concentrations were used to stimulate human mesangial cells (HMCs), demonstrated a significant increase in the protein level of high mobility group box 1 (HMGB1) and a marked decrease in miR-216a-5p expression (all P < 0.05). …”

Altering rRNA 2’O-methylation pattern during neuronal differentiation is regulated by FMRP by Michelle Ninochka D’Souza (22365912)

“…<p>The Fragile X Messenger Ribonucleoprotein (FMRP) is a selective RNA-binding protein that localizes to the cytoplasm and the nucleus. …”

Table 1_Shenfu injection promotes self-renewal of intestinal stem cells in sepsis-induced intestinal injury via inducing ATF4 expression.docx by Yunxin Deng (11052077)

“…</p>Results<p>Plasma levels of D-lactate and intestinal-type fatty acid-binding protein (I-FABP) in septic patients with intestinal dysfunction were significantly reduced following SFI administration. …”

Data Sheet 1_Immunolocalization and proteomic analyses of IZUMO1 in porcine spermatozoa.pdf by Miranda Hernández-Falcó (21373568)

“…As a result of the capacitation, there was a significant decrease in P1. Conversely, in ARS, IZUMO1 was dominantly distributed in P3 51.55% and P4 24.25%. …”

Table3_Cytochrome P450 VvCYP76F14 dominates the production of wine bouquet precursors in wine grapes.docx by Guangli Xia (19834830)

“…Site-directed mutation of 4 amino acid residues (I120L, L298V, E378G, and T389A) in VvCYP76F14 resulted in a significant decrease in VvCYP76F14 enzymatic activities, respectively. …”

Table2_Cytochrome P450 VvCYP76F14 dominates the production of wine bouquet precursors in wine grapes.docx by Guangli Xia (19834830)

“…Site-directed mutation of 4 amino acid residues (I120L, L298V, E378G, and T389A) in VvCYP76F14 resulted in a significant decrease in VvCYP76F14 enzymatic activities, respectively. …”