Data Sheet 2_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Data Sheet 3_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Data Sheet 1_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Data Sheet 1_CaMYBA–CaMYC–CaTTG1 complex activates the transcription of anthocyanin synthesis structural genes and regulates anthocyanin accumulation in pepper (Capsicum annuum L.)... by Xiaowei Ma (113432)

“…Further analysis showed that CaMYBA could activate the expression of CaMYC by binding to its promoter. Overall, our study expands the understanding of the regulatory mechanism of anthocyanin synthesis in pepper leaves and has important significance for creating more pepper plants with different color patterns by gene editing engineering.…”

Table 1_Patient and donor antibody profiles in early COVID-19 convalescent plasma therapy in the COnV-ert trial.pdf by Andrea Alemany (11836601)

“…</p>Results<p>Treatment with CCP significantly increased the levels of IgG and IgG1 to receptor-binding domain (RBD) and S, IgG3 to S and S2, and IgG avidity in recipients 7 days after infusion, without an increase in IgA, IgM, IgG2, IgG4, or neutralization. …”

CPSF6-NLS chimeras confer virus-specific infectivity defects. by Nicholas Rohlfes (20577485)

“…<p>(A) Infection with HIV-1 CA mutant N74D luciferase-reporter virus in growth arrested HeLa cells reveals a dependence on CA-CPSF6 binding for the observed changes in WT HIV-1 infectivity. …”

Table 1_DYRK1A roles in human neural progenitors.xlsx by Jeremie Courraud (20871932)

“…In addition, DYRK1A-KD led to a reduction in p21 protein levels, despite an increase in the expression of a minor transcript variant for this gene, and a decrease in ERK pathway activation.</p>Discussion<p>Together, the DYRK1A interactome in hNSCs and the gene expression changes induced by its depletion highlight the significant role of DYRK1A in regulating hNSC proliferation. …”

Table 1_The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.docx by Liuzhen Yang (20449762)

“…The results showed a significant decrease in fasting blood glucose levels (SMD = −0.79, 95% CI: −1.11 to −0.46). …”

Related to Fig 3. by Mohammad Nafees Ansari (22232505)

“…(<b>O</b>, <b>P</b>) Cell proliferation assay confirms an increase in cell proliferation of BT-474_ZFX^OE cells (mean ± SEM, <i>n</i> = 5) (O), whereas BT-474_ZFX^SL cells (mean ± SEM, <i>n</i> = 3) show decreased cell proliferation (P). (<b>Q</b>) Tumor growth kinetics recorded a significantly higher growth of BT-474_ZFX^OE (mean ± SEM, <i>n</i> = 5) than BT-474_VECT^OE tumors. …”

raw data of "Helicobacter hepaticus promotes hepatic steatosis through CdtB-induced mitochondrial stress and lipid metabolism reprogramming" by Quan Zhang (20376574)

“…Moreover, the neutralization of CdtB significantly alleviates hepatic lipidosis in mice upon H. hepaticus infection. …”

Data Sheet 3_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”

Data Sheet 4_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”

Data Sheet 2_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”

Data Sheet 1_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”

Image6_Overexpression of TaPIP1A enhances drought and salt stress tolerance in Arabidopsis: cross-species conservation and molecular dynamics.jpeg by Jie Han (128758)

“…In TaPIP1A knockout wheat strains, there was a significant decrease in stress tolerance, whereas Arabidopsis plants overexpressing TaPIP1A exhibited marked improvements in survival under similar stress conditions. …”

Image3_Overexpression of TaPIP1A enhances drought and salt stress tolerance in Arabidopsis: cross-species conservation and molecular dynamics.jpeg by Jie Han (128758)

“…In TaPIP1A knockout wheat strains, there was a significant decrease in stress tolerance, whereas Arabidopsis plants overexpressing TaPIP1A exhibited marked improvements in survival under similar stress conditions. …”

Image4_Overexpression of TaPIP1A enhances drought and salt stress tolerance in Arabidopsis: cross-species conservation and molecular dynamics.jpeg by Jie Han (128758)

“…In TaPIP1A knockout wheat strains, there was a significant decrease in stress tolerance, whereas Arabidopsis plants overexpressing TaPIP1A exhibited marked improvements in survival under similar stress conditions. …”

Table3_Overexpression of TaPIP1A enhances drought and salt stress tolerance in Arabidopsis: cross-species conservation and molecular dynamics.docx by Jie Han (128758)

“…In TaPIP1A knockout wheat strains, there was a significant decrease in stress tolerance, whereas Arabidopsis plants overexpressing TaPIP1A exhibited marked improvements in survival under similar stress conditions. …”

Table2_Overexpression of TaPIP1A enhances drought and salt stress tolerance in Arabidopsis: cross-species conservation and molecular dynamics.docx by Jie Han (128758)

“…In TaPIP1A knockout wheat strains, there was a significant decrease in stress tolerance, whereas Arabidopsis plants overexpressing TaPIP1A exhibited marked improvements in survival under similar stress conditions. …”

Image5_Overexpression of TaPIP1A enhances drought and salt stress tolerance in Arabidopsis: cross-species conservation and molecular dynamics.jpeg by Jie Han (128758)

“…In TaPIP1A knockout wheat strains, there was a significant decrease in stress tolerance, whereas Arabidopsis plants overexpressing TaPIP1A exhibited marked improvements in survival under similar stress conditions. …”