Table 6_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xls حسب Lan Wang (85307)

"…By analyzing CLIP-seq and RNA-seq data, we found that hnRNP-F may inhibit gene expression by binding to lncRNA SNHG1. Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Table 2_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.docx حسب Lan Wang (85307)

"…By analyzing CLIP-seq and RNA-seq data, we found that hnRNP-F may inhibit gene expression by binding to lncRNA SNHG1. Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Table 4_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xlsx حسب Lan Wang (85307)

"…By analyzing CLIP-seq and RNA-seq data, we found that hnRNP-F may inhibit gene expression by binding to lncRNA SNHG1. Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Data Sheet 1_Thymoquinone/β-N-acetylglucosaminidase, a novel plant-derived combination, inhibited quorum sensing signaling pathways and disrupted biofilm in Staphylococcus aureus.p... حسب Adel Attia M. Ahmad (16729177)

"…Computer simulations revealed that the TQ ligand was a potent inhibitor of QS molecules, binding tightly to agrA and sarA. Notably, NAGase, whether used alone or in conjunction with TQ, led to a decrease in the expression of the atl, icaA, and agr genes.…"

Image 5_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif حسب Zhiyi Wang (328693)

"…Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …"

Development and characterization of a bivalent mRNA vaccine targeting the Delta and Omicron variants of SARS-CoV-2 حسب Xiao-Chuan Xiong (22337097)

"…<p>The emergence of the Omicron variant of SARS-CoV-2 has led to a decrease in vaccine efficacy and contributed to the ongoing epidemic of COVID-19. …"

Table 1_Thymoquinone/β-N-acetylglucosaminidase, a novel plant-derived combination, inhibited quorum sensing signaling pathways and disrupted biofilm in Staphylococcus aureus.docx حسب Adel Attia M. Ahmad (16729177)

"…Computer simulations revealed that the TQ ligand was a potent inhibitor of QS molecules, binding tightly to agrA and sarA. Notably, NAGase, whether used alone or in conjunction with TQ, led to a decrease in the expression of the atl, icaA, and agr genes.…"

Image 2_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif حسب Zhiyi Wang (328693)

"…Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …"

Data Sheet 1_Siglec-E augments adipose tissue inflammation by modulating TRAF3 signaling and monocytic myeloid-derived suppressor cells during obesity.pdf حسب Ahmed Rakib (10876047)

"…</p>Results<p>HFD consumption significantly increased the body weight and blood glucose levels in siglec-E KO mice relative to those of WT mice. …"

Table 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.docx حسب Zhiyi Wang (328693)

"…Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …"

Image 3_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif حسب Zhiyi Wang (328693)

"…Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …"

Image 4_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif حسب Zhiyi Wang (328693)

"…Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …"

Image 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif حسب Zhiyi Wang (328693)

"…Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …"

Fos does not interact with Jun but homodimerizes post axotomy. حسب Gibarni Mahata (19486154)

"…If proteins attached to the BiFC fragments do not bind one another, then no fluorophore is generated (bottom). …"

Data Sheet 1_FOXA2/miR-148a-3p/SMURF2 signaling feed-forward loop alleviates spinal cord ischemia-reperfusion injury-induced neuropathic pain by modulating microglia polarization i... حسب Xiaotong Hao (20650807)

"…</p>Results<p>SCIRI significantly reduced mechanical and thermal pain thresholds in rats and promoted microglial polarization, with a concomitant decrease in SIRT1 expression and an increase in SMURF2 expression in microglial cells. …"

Data Sheet 2_FOXA2/miR-148a-3p/SMURF2 signaling feed-forward loop alleviates spinal cord ischemia-reperfusion injury-induced neuropathic pain by modulating microglia polarization i... حسب Xiaotong Hao (20650807)

"…</p>Results<p>SCIRI significantly reduced mechanical and thermal pain thresholds in rats and promoted microglial polarization, with a concomitant decrease in SIRT1 expression and an increase in SMURF2 expression in microglial cells. …"

Data Sheet 1_Integrated computational and experimental identification of N-[(1H-1,2,4-triazol-3-yl)phenyl]-1-(1H-pyrazolo[3,4-b]pyridin-3-yl)methanamide as a potent and selective T... حسب Xinxin Ying (21507500)

"…Survival analysis revealed a significant correlation between elevated TIM-3 expression and decreased patient survival. …"

多杀性巴氏杆菌流行过程中水平基因转移对其毒力与耐药的影响-附录.xlsx حسب He Jiao (19924953)

"…The transcription levels of iron acquisition systems such as fecABCDE, sitABCD operons, and dppAB were also significantly reduced, but the afuAB-dependent periplasmic binding protein-mediated iron transport mechanism was significantly upregulated. …"

3D culture raw data حسب Yaojun Luo (20296512)

"…In contrast, mRNAs of insulin-like growth factor 2 mRNA-binding proteins (<i>Igf2bps</i>), which encode RNA-binding proteins, showed a significant reduction in 2D monolayer cultured eWAT precursor cells, a pattern distinct from that of 3T3-L1 preadipocytes. …"

<b>Supporting data for ''The pathogenicity and pathogenic mechanism of SARS-CoV-2 Omicron''</b> حسب Bingjie Hu (10835565)

"…Further mechanistic investigations reveal that the Omicron subvariant is ineffective in using TMPRSS2 compared with ancestral SARS-CoV-2 (HKU-001a) and previous variants, which may contribute to its decreased replication in Calu3 and Caco2 cells. In K18-hACE2 transgenic mice, the replication capacity of the Omicron subvariant is significantly attenuated in both the upper and lower respiratory tracts of virus-infected animals when compared to that of the ancestral strain and Delta (B.1.617.2) variant, correlating with substantially ameliorated lung pathology. …"