يعرض 20,641 - 20,660 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant burden decrease ))', وقت الاستعلام: 0.56s تنقيح النتائج
  1. 20641

    Supplementary file 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.docx حسب Yan Li (23143)

    منشور في 2025
    "…Furthermore, intermediate or healthy lifestyles significantly decreased the age-related risk of stroke, chronic liver disease, chronic kidney disease (CKD), osteoporosis, osteoarthritis, and hypertension. …"
  2. 20642

    Supplementary Material for: From childhood to adolescence: Long-term trends in severe obesity in German youth (2002–2023) حسب figshare admin karger (2628495)

    منشور في 2025
    "…Results Pre-pandemic, SO remained stable or declined in children under 12 until 2010: OR5: 0.8-1, p<0.001) but rose significantly afterward (OR5: 1.1-1.2, p<0.001). Children between 12-16 years of age showed a continuous increase, especially boys (boys12-16: OR5: 1.3, girls12-16: OR5: 1.1, p<0.001). …"
  3. 20643

    Supplementary file 1_Effects of aging and valence on emotional response inhibition: conclusions from a novel stop-signal task.xlsx حسب Jill D. Waring (6652103)

    منشور في 2025
    "…Aging is associated with decreasing cognitive control and inhibition alongside improvements in emotional control and regulation. …"
  4. 20644

    A Hydrate-Bearing Sediment Gas Replacement Mechanical Behavior Regulation Mechanism and Slope Stability Analysis حسب Lei Huang (35191)

    منشور في 2025
    "…As saturation increases, the Γ value of the critical state line decreases, while the λ value increases. (3) For slope simulations, increased hydrate saturation significantly raises the safety factor for gentler slopes, while the reinforcing effect of gas replacement is weaker for steeper slopes with higher saturation.…"
  5. 20645

    Image1_Neutrophil-activating protein in Bacillus spores inhibits casein allergy via TLR2 signaling.jpeg حسب Zhuwei Liang (8762337)

    منشور في 2024
    "…</p>Results<p>NAP recombinant spore treatment significantly reduced allergic symptoms and intestinal inflammation. …"
  6. 20646

    Table 2_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx حسب Ying Dong (41989)

    منشور في 2025
    "…</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …"
  7. 20647

    Data Sheet 6_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx حسب Liqin Liang (652560)

    منشور في 2025
    "…Conversely, silencing the ortholog gene NbSOS1-13 in Nicotiana benthamiana showed more accumulation of ROS, serious cell necrosis, reduced activities of SOD and CAT, significantly increased MDA level, obvious leaf wilting, decreased tolerance to infection, and reduced leaf stomatal closure rate and accelerated stomatal area. …"
  8. 20648

    Image2_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

    منشور في 2025
    "…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …"
  9. 20649

    Image6_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

    منشور في 2025
    "…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …"
  10. 20650

    Image 1_Interaction between dietary selenium intake and age on severe headache or migraine in the United States: a population-based study.pdf حسب Xinping Yu (555177)

    منشور في 2025
    "…</p>Conclusion<p>A higher dietary selenium intake is significantly associated with a decreased prevalence of migraine, and age can modify the association between them. …"
  11. 20651

    Data Sheet 1_Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders.docx حسب Nikola Habek (21178259)

    منشور في 2025
    "…In this study, we aim to determine the expression of uroguanylin (UGN) in the mouse and human brain, its regulatory mechanisms, and its significance to patients with obesity and type 2 diabetes (T2D).…"
  12. 20652

    Table 6_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx حسب Miguel Ângelo-Dias (20936444)

    منشور في 2025
    "…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"
  13. 20653

    Supplementary Material for: Role of Raf Kinase Inhibitor Protein in Modulating Echinococcal Cyst Fluid-induced Degranulation in Bone Marrow-Derived Mast Cells حسب figshare admin karger (2628495)

    منشور في 2025
    "…Following sensitization, BMMCs from the KO group demonstrated significantly higher degranulation rates compared to the WT group (p < 0.05). …"
  14. 20654

    Table1_Variation of leaf shape with tree size: a case study using Camptotheca acuminata Decne.xlsx حسب Ke He (331344)

    منشور في 2024
    "…However, DBH did not significantly affect the ratio W/L nor the leaf roundness index. …"
  15. 20655

    Data Sheet 1_Phyllosphere microbiome responses to nano-berberine and chemical fungicides in powdery mildew infected strawberry.pdf حسب Meng Yang (162251)

    منشور في 2025
    "…The results showed that nano-fungicide application significantly reduced the disease index of powdery mildew and markedly decreased its incidence in field-grown strawberries, ultimately lowering leaf disease incidence to 5.06% with a control efficacy of 96.81%. …"
  16. 20656

    Effect of HPC silencing on phase-locking of PFC neurons to local theta. حسب Susanne S. Babl (21169261)

    منشور في 2025
    "…Percentage of neurons significantly phase-locked to PFC theta oscillations (4–12 Hz) in the sample <b>(A)</b> and choice phase <b>(B)</b> during light-off and light-on trials. …"
  17. 20657

    Table 7_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx حسب Linling Du (22827035)

    منشور في 2025
    "…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
  18. 20658

    pH sensitive lipid polymeric hybrid nanoparticle (LPHNP) of paclitaxel and curcumin for targeted delivery in breast cancer حسب Hrishikesh Sarma (14827761)

    منشور في 2024
    "…MTT-assay studies revealed enhanced cytotoxicity of CUR and PTX as LPHNPs showing IC<sub>50</sub> value of free CUR & PTX 480.06 µg/mL decreasing to 282.97 µg/mL for CS-CUR-PTX-LPHNPs. <i>In vivo</i> pharmacokinetic evaluations in rats confirmed significantly improved bioavailability, with a 3.8-fold increase in AUC for CUR and a 6.6-fold increase for PTX. …"
  19. 20659

    Spectral shift of fluorophore NHS-esters. حسب Hyunwoo Kim (690467)

    منشور في 2025
    "…After 5 min of illumination with a 561-nm excitation laser, the fluorescence signal in the 647-nm detection channel decreased, while the signal in the 561-nm detection channel significantly increased, indicating a spectral blue-shift of the emission spectrum. …"
  20. 20660

    Data Sheet 2_Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke.zip حسب Fengli Ye (22123540)

    منشور في 2025
    "…Machine learning identified four hub genes—LEF1, ITGAX, BLVRB, and ATF4. All were significantly upregulated in ICH tissues and plasma, correlating with immune cell infiltration. …"