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661
Data Sheet 1_The disproportionate burden of pulmonary arterial hypertension among the elderly: global, regional, and national trends from 1990 to 2021—findings from the 2021 global...
Published 2025“…This condition imposes a substantial economic burden and significant health challenges globally. …”
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662
Data Sheet 1_Global, regional, and national burden of thyroid cancer in women of child-bearing age, 1990 to 2021 and predictions to 2035: An analysis of the global burden of diseas...
Published 2025“…The Estimated Annual Percentage Change (EAPC) for ASIR was 1.47, indicating an increasing trend, whereas the EAPCs for ASMR and ASDR were -0.35 and -0.05, showing decreasing trends. The burden of thyroid cancer among patients with women of child-bearing age exhibited a significant age-related trend, peaking in the 45–49 age group. …”
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663
Supplementary file 1_Global, regional, and national burden of iodine deficiency for women of reproductive age, 1990–2021: a systematic analysis based on the Global Burden of Diseas...
Published 2025“…Objective<p>This study aims to assess the global, regional, and national burden of iodine deficiency among women of reproductive age (WRA) from 1990 to 2021.…”
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664
Data Sheet 1_Evolving trends and burden of idiopathic epilepsy among children (0–14 years), 1990–2021: a systematic analysis for the Global Burden of Disease study 2021.zip
Published 2025“…In contrast, ASPR (AAPC = −0.03), ASMR (AAPC = −1.60), and ASDR (AAPC = −1.01) all decreased. Regionally, the low-middle SDI region had the highest burden, while the high SDI region had the highest ASIR and ASPR. …”
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665
Table 1_Global, regional, and national anemia burden among women of reproductive age (15–49 years) from 1990 to 2021: an analysis of the Global Burden of Disease Study 2021.docx
Published 2025“…We also evaluated the association between anemia burden and the socio-demographic index (SDI), quantified temporal trends of anemia burden from 1990 to 2021, and projected future burden to 2030.…”
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666
Uptake of the intervention (N = 49).
Published 2025“…There was a 1.32 unit (<i>p</i> = 0.085) decrease in depressive symptoms and a reduction in caregiver burden (β = -1.28, <i>p</i> = 0.020) in the intervention arm. …”
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667
Baseline characteristics of sample by trial arm.
Published 2025“…There was a 1.32 unit (<i>p</i> = 0.085) decrease in depressive symptoms and a reduction in caregiver burden (β = -1.28, <i>p</i> = 0.020) in the intervention arm. …”
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668
CweL trial design.
Published 2025“…There was a 1.32 unit (<i>p</i> = 0.085) decrease in depressive symptoms and a reduction in caregiver burden (β = -1.28, <i>p</i> = 0.020) in the intervention arm. …”
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669
Participant Flow.
Published 2025“…There was a 1.32 unit (<i>p</i> = 0.085) decrease in depressive symptoms and a reduction in caregiver burden (β = -1.28, <i>p</i> = 0.020) in the intervention arm. …”
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670
Economic cost composition by arm and outcomes.
Published 2025“…There was a 1.32 unit (<i>p</i> = 0.085) decrease in depressive symptoms and a reduction in caregiver burden (β = -1.28, <i>p</i> = 0.020) in the intervention arm. …”
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671
Image 1_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with foreca...
Published 2025“…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …”
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672
Table 1_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with foreca...
Published 2025“…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …”
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673
Image 3_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with foreca...
Published 2025“…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …”
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674
Image 2_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with foreca...
Published 2025“…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …”
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675
Supplementary file 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burd...
Published 2025“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”
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676
Data Sheet 1_Global burden of disease for colorectal cancer due to diet low in whole grains from 1990 to 2021 and its projections to 2050: analysis of the global burden of disease...
Published 2025“…Age analysis shows that the disease burden is highest in the 50–85 age group, with males having a significantly higher risk than females. …”
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677
Table 1_Global burden of reported lower respiratory system fungal infection.docx
Published 2025“…</p>Results<p>On a global scale, the burden of lower respiratory fungal infections decreased significantly from 1990 to 2021, with a decline in mortality rates. …”
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678
Supplementary Material for: The impact of mesalazine pill burden on compliance in inflammatory bowel disease patients
Published 2025“…Conclusion: The results showed a consistent higher adherence with the decrease of pill burden. High strength tablets were significantly associated with higher persistence and higher adherence to medication compared to the medium and low strength tablet group.…”
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679
Data Sheet 1_Global, regional and national burden of decubitus ulcers in 204 countries and territories from 1990 to 2021: a systematic analysis based on the global burden of diseas...
Published 2025“…Background<p>Decubitus ulcers, also known as pressure ulcers, pose a significant public health challenge due to their substantial impact on morbidity, mortality, and healthcare expenditures.…”
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680
Data Sheet 1_Analysis of temporal and spatial changes in the global burden of hypertensive heart disease based on data from the Global Burden of Disease study database and future p...
Published 2025“…According to the APC model, the worldwide incidence of hypertensive heart disease is expected to increase from 2022 to 2046, with further decreases in deaths and DALYs.</p>Conclusions<p>This study systematically reveals the increasing trend in the incidence of hypertensive heart disease globally between 1990 and 2021 and confirms the significant impact of sex and socioeconomic development level on its burden. …”