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significant burdens » significant burden (Expand Search), significant barriers (Expand Search), significant binding (Expand Search)
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1041
Data Sheet 1_Global burden and future trends of gastric cancer in women of reproductive age: estimates from the GBD 2021 Study, 1990–2050.zip
Published 2025“…</p>Results<p>From 1990 to 2021, the GC burden in women aged 15–49 declined globally: ASPR decreased from 10.42 to 5.41 per 100,000 (EAPC −2.11), ASIR from 4.61 to 2.13 (EAPC −2.56), ASMR from 2.02 to 0.89 (EAPC −3.02), and ASDR from 59.6 to 23.8 per 100,000 (EAPC −3.00). …”
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1042
Data Sheet 1_Prevalence trend and burden of foodborne trematodiasis in China from 1990 to 2021 and its predictions until 2030: a comparative study with Japan and South Korea.csv
Published 2025“…</p>Conclusion<p>The study reveals contrasting trends in FBT burden among the three East Asian countries, with significant declines in China, a slight decrease in South Korea despite higher-than-global rates, and an increasing but low burden in Japan. …”
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1043
Data Sheet 2_Prevalence trend and burden of foodborne trematodiasis in China from 1990 to 2021 and its predictions until 2030: a comparative study with Japan and South Korea.docx
Published 2025“…</p>Conclusion<p>The study reveals contrasting trends in FBT burden among the three East Asian countries, with significant declines in China, a slight decrease in South Korea despite higher-than-global rates, and an increasing but low burden in Japan. …”
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1044
Table 1_Diverging trends in the global burden of ischemic heart disease attributable to non-optimal temperatures: a historical analysis (1990–2021) and 2050 projections.docx
Published 2025“…Significant socioeconomic disparities were observed, with low-to-middle SDI regions bearing a disproportionate share (75.0%) of the global high non-optimal temperature-related mortality burden. …”
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1045
Global Mortality and DALYs for CVD by Sex (1990-2021).
Published 2025“…Females experienced a consistently higher burden, with significantly higher age-standardized mortality rates and DALY values compared to males, emphasizing persistent gender disparities in CVD outcomes related to LPA.…”
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1046
Supplementary file 1_Global, regional, and national trends for childhood myocarditis from 1990 to 2021: health inequality and age-period-cohort analysis for the Global Burden of Di...
Published 2025“…Health inequalities related to the sociodemographic index (SDI) and APC effect for CM burden were studied in this study.</p>Findings<p>A significant decreasing trend for ASR of incidence, prevalence, mortality, and DALYs from 1990 to 2021 was found for CM globally. …”
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1047
Table 1_Evaluating the global, regional, and national burden of congenital heart disease in infants younger than 1 year: a 1990–2021 systematic analysis for the GBD study 2021.docx...
Published 2025“…By 2021, its mortality rates had decreased to the eighth leading cause of death.</p>Interpretation<p>CHD remains a significant and rapidly escalating global challenge in child health. …”
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1048
Data Sheet 1_Evaluating the global, regional, and national burden of congenital heart disease in infants younger than 1 year: a 1990–2021 systematic analysis for the GBD study 2021...
Published 2025“…By 2021, its mortality rates had decreased to the eighth leading cause of death.</p>Interpretation<p>CHD remains a significant and rapidly escalating global challenge in child health. …”
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1049
Data Sheet 2_Evaluating the global, regional, and national burden of congenital heart disease in infants younger than 1 year: a 1990–2021 systematic analysis for the GBD study 2021...
Published 2025“…By 2021, its mortality rates had decreased to the eighth leading cause of death.</p>Interpretation<p>CHD remains a significant and rapidly escalating global challenge in child health. …”
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1050
Table 2_Mortality and trends of pulmonary arterial hypertension, 1990–2021: a population-based study.docx
Published 2025“…</p>Methods<p>The estimates and their 95% uncertainty interval for case number of PAH were collected from the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2021. …”
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1051
Table 1_Mortality and trends of pulmonary arterial hypertension, 1990–2021: a population-based study.docx
Published 2025“…</p>Methods<p>The estimates and their 95% uncertainty interval for case number of PAH were collected from the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2021. …”
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1052
Table 3_Mortality and trends of pulmonary arterial hypertension, 1990–2021: a population-based study.docx
Published 2025“…</p>Methods<p>The estimates and their 95% uncertainty interval for case number of PAH were collected from the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2021. …”
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1053
Table 1_A population database analysis to describe the residual burden of varicella in Italy—a high vaccination coverage area—from 2004 to 2022.docx
Published 2025“…In the Veneto Region, following the implementation of VV in 2006, the IR significantly decreased by 20.5 annually (95% CI: −23.4, −17.5), ranging from 50.2 per 1,000 person-years in 2006 to 1.2 per 1,000 person-years in 2022.…”
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1054
Table 1_Global burden of pneumoconiosis from 1990 to 2021: a comprehensive analysis of incidence, mortality, and socio-demographic inequalities in 204 countries and territories.doc...
Published 2025“…No correlation was found between the SDI values and the pneumoconiosis burden. Additionally, absolute inequality among SDI countries decreased from 1990 to 2021, whereas relative inequality demonstrated an upward trend during the same period.…”
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1055
Image 3_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg
Published 2025“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”
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1056
Image 2_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg
Published 2025“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”
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1057
Image 4_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg
Published 2025“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”
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1058
Image 1_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg
Published 2025“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”
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1059
Table 1_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.docx
Published 2025“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”
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1060
Table 1_Global, regional, and national esophageal cancer deaths and DALYs attributable to diet low in vegetables and fruits, 1990–2019: analysis for the global burden of disease st...
Published 2025“…The associated DALYs totaled 16,065,68, representing 0.06% of total global DALYs, with an age-standardized DALY rate of 19.24. The disease burden attributable to insufficient fruit intake (51,210 deaths, 12,497,75 DALYs) was significantly higher than that from inadequate vegetable intake (17,176 deaths, 4,203,09 DALYs). …”