Table 2_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf حسب Qiao Ma (136536)

"…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …"

Data Sheet 1_Disproportionate impact of the COVID-19 pandemic on socially vulnerable communities: the case of Jane and Finch in Toronto, Ontario.docx حسب Zahra Movahedi Nia (9238798)

"…The number of patients during the COVID-19 pandemic versus before that decreased significantly more for pop-smear tests (p = 0.041) and surgery waitlists (p = 0.037) for the Jane and Finch community.…"

Data Sheet 1_Evaluation of the epidemiological and economic impact of the ADLIFE intervention on medium- to long-term in patients with advanced chronic disease.pdf حسب Igor Larrañaga (5434382)

"…Emergency visits and consultations with primary care professionals decreased significantly, while specialist consultations increased. …"

Data Sheet 1_Impact of leukemia subtype and demographics on patient quality of life in 76 countries: a cross-sectional study.pdf حسب Sam Salek (5800727)

"…Background<p>Disease-specific factors associated with decreased quality of life (QoL) in patients with leukemia have not been studied in a large-scale, global, observational study.…"

Data Sheet 2_Impact of leukemia subtype and demographics on patient quality of life in 76 countries: a cross-sectional study.docx حسب Sam Salek (5800727)

"…Background<p>Disease-specific factors associated with decreased quality of life (QoL) in patients with leukemia have not been studied in a large-scale, global, observational study.…"

Molecular characterization of zinc metalloproteinase Nas-14 from Trichinella spiralis and its participation in intestinal invasion حسب Qingbo Lv (21676001)

"…In addition, the direct incubation of rTsNas14 with claduin-1 showed that rTsNas14 could significantly degrade claudin-1. In vivo studies have demonstrated that inhibition of TsNas14 expression significantly impairs the infectivity of T. spiralis in mice, resulting in a decreased AW and muscle larval burden. …"

Supplementary file 1_Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III tria... حسب Huaxiang Liu (322464)

"…</p>Conclusion<p>Ivarmacitinib significantly reduces the need for adding/escalating medications compared to placebo, thereby potentially decreasing treatment burden. …"

Image 1_Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III trial.tif حسب Huaxiang Liu (322464)

"…</p>Conclusion<p>Ivarmacitinib significantly reduces the need for adding/escalating medications compared to placebo, thereby potentially decreasing treatment burden. …"

Data Sheet 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.xlsx حسب Demos Kynigopoulos (12420457)

"…Gliclazide reduced neuroinflammation and partially preserved glial and neuronal markers. Both treatments decreased amyloid burden and modulated adipokine levels, with Alirocumab elevating leptin and omentin in brain and serum. …"

Image 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.jpeg حسب Shenglan He (7641308)

"…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …"

Table 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.xlsx حسب Shenglan He (7641308)

"…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …"

Supplementary file 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.docx حسب Demos Kynigopoulos (12420457)

"…Gliclazide reduced neuroinflammation and partially preserved glial and neuronal markers. Both treatments decreased amyloid burden and modulated adipokine levels, with Alirocumab elevating leptin and omentin in brain and serum. …"

Image 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.tiff حسب Yulia Dwi Setia (21590591)

"…Maximal parasite accumulation in the proximal colon was observed at 8 dpi in histological examination as well as qPCR. Colon length was significantly shortened at 3 dpi. Goblet cell area significantly reduced at 8 dpi (p < 0.05). …"

Table 2_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.xlsx حسب Yulia Dwi Setia (21590591)

"…Maximal parasite accumulation in the proximal colon was observed at 8 dpi in histological examination as well as qPCR. Colon length was significantly shortened at 3 dpi. Goblet cell area significantly reduced at 8 dpi (p < 0.05). …"

Supplementary file 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.pdf حسب Yulia Dwi Setia (21590591)

"…Maximal parasite accumulation in the proximal colon was observed at 8 dpi in histological examination as well as qPCR. Colon length was significantly shortened at 3 dpi. Goblet cell area significantly reduced at 8 dpi (p < 0.05). …"

Data Sheet 1_Exploring long COVID in pediatric patients: clinical insights from a long COVID clinic.docx حسب Dina Kamel (22434430)

"…Female patients more frequently reported brain fog, dizziness, palpitations, and postural orthostatic tachycardia syndrome. Overall symptom burden decreased significantly over time (p < 0.001). …"

Data Sheet 1_Exploring the effects of exercise on T cell function and metabolism in cancer: a scoping review protocol.pdf حسب J. L. Low (22141795)

"…Background<p>The global burden of cancer is escalating, and improved strategies for disease prevention and treatment are needed. …"

Data Sheet 1_Pan-cancer analysis reveals TRA16 as a master regulator of human carcinogenesis.pdf حسب Yanyan Zhu (32035)

"…In liver cancer organoid models, TRA16 and its co-expressed genes were significantly upregulated. Intercellular communication analysis showed that TRA16-positive cells exhibited increased autocrine signaling and overall signaling activity. …"

Data Sheet 1_Landscape analysis of m6A modification regulators reveals LRPPRC as a key modulator in tubule cells for DKD: a multi-omics study.docx حسب Li Jiang (120930)

"…Background<p>Diabetic Kidney Disease (DKD) is a serious complication of diabetes, imposing a substantial medical burden. The significance of N6-methyladenosine (m6A) modification in the pathogenesis of DKD has become increasingly prominent.…"

Table 1_The germinal center-tertiary lymphoid structure after neoadjuvant chemo-immunotherapy for locally advanced lung squamous cell carcinoma can predict the disease progression.... حسب Lili Jiang (65114)

"…In addition, there was an inverted U-shaped correlation between GC-TLS and treatment cycle: the density of GC-TLSs reaches the peak value after receiving two or less (≤ 2) cycles of NACT and NACT-IO, and decreased significantly after receiving more than two (> 2) cycles of NACT and NACT-IO (p<0.05). …"