Age-standardized mortality rates (ASMR), age-standardized disability-adjusted life year rates (ASDR), and their 95% uncertainty intervals (UIs) by disease stage in China from 1990... by Xinyue Qi (9637055)

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BAPC model projections of mortality and DALYs rates for each disease stage in China from 2022 to 2035, with 50%, 60%, 70%, 80%, and 95% uncertainty intervals. by Xinyue Qi (9637055)

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Temporal trends of DALYs of the total burden related to hepatitis B and three disease stages for all ages and across four age groups (<35, 35–49, 50–69, and ≥70 years) from 1990 to... by Xinyue Qi (9637055)

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Predictions for the annual age-standardized disability-adjusted life years (ASDR) attributable to hepatitis B virus (HBV) infection in China until 2035 on the basis of the Bayesian... by Xinyue Qi (9637055)

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This diagram summarizes the main steps of our study, including data sourcing from the GBD 2021 database, stratified processing by disease stage, age, and sex, application of EAPC a... by Xinyue Qi (9637055)

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Cohort characteristics. by Fernanda Talarico (807333)

“…</p><p>Results</p><p>The analysis reveals a significant decrease in all health services utilization from 2016 to 2019, followed by an increase until 2022. …”

Raw data of Fig 2-Fig 13 in this study. by Wen Wen Zheng (17721404)

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DAS and Y27632 down-regulated the mRNA and protein expression of CK8-RhoA/ROCK1 pathway and up-regulated TJs expression in intestines of infected mice. by Wen Wen Zheng (17721404)

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qPCR analysis of CK8 knockdown affecting Clauding-1 mRNA expression. by Wen Wen Zheng (17721404)

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Molecular-docking simulation of the TsSPc–CK8 complex in Caco-2 cells. by Wen Wen Zheng (17721404)

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CK8 knockdown and ROCK1 inhibitor abolished rTsSPc-reduced TJs expression in Caco-2 monolayers by IFA. by Wen Wen Zheng (17721404)

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PAS staining of intestinal sections from <i>T. spiralis</i>-infected mice pretreated with DAS and Y27632. by Wen Wen Zheng (17721404)

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qPCR and Western blotting of CK8 knockdown blocking the rTsSPc-activated pathway and -reduced TJs expression. by Wen Wen Zheng (17721404)

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IFA, GST pull-down and Co-IP assay of specific binding between rTsSPc and CK8. by Wen Wen Zheng (17721404)

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Transcription and expression levels of CK8 in Caco-2 cells after CK8 gene was knocked down. by Wen Wen Zheng (17721404)

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qPCR and Western blotting of activation of CK8 receptor and RhoA/ROCK1 pathway proteins in Caco-2 cells treated with rTsSPc and IIL ES antigens. by Wen Wen Zheng (17721404)

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CK8 knockdown and ROCK1 inhibitor suppressed rTsSPc-induced disruption of the Caco-2 monolayer and blocked rTsSPc-promoted IIL invasion. by Wen Wen Zheng (17721404)

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HE staining showed that DAS and Y27632 alleviated intestinal inflammation in <i>T. spiralis</i>-infected mice. by Wen Wen Zheng (17721404)

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The ROCK1 pathway inhibitor Y27632 prevented rTsSPc from activating the ROCK1 pathway and reducing TJs expression. by Wen Wen Zheng (17721404)

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qPCR (A-D) and ELISA (E-H) detection of inflammatory cytokines in intestine of <i>T. spiralis</i>-infected mice. by Wen Wen Zheng (17721404)

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