Image 2_Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7... by Chunmei Ren (10921089)

“…</p>Results<p>Metformin significantly reduced periapical bone destruction on postoperative days 21 and 28, and decreased the number of osteoclasts on the periapical alveolar bone on postoperative day 28. …”

Image 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Moreover, depletion of LAMs attenuated iron overload caused acceleration of AML progression.</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…”

Image 5_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Moreover, depletion of LAMs attenuated iron overload caused acceleration of AML progression.</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…”

Image 1_Fraxin modulates lipid metabolism as well as gut flora to avert NAFLD.tif by Yang Jing (2231179)

“…GO and KEGG analyses suggested that fraxin primarily treats NAFLD by modulating lipid metabolism and atherosclerosis-related signaling pathways. In vivo, fraxin significantly lowered liver index and visceral fat accumulation, reduced serum levels of “interleukin-6 (IL-6),” “aspartate aminotransferase,” “tumor necrosis factor-α (TNF-α)” and “alanine aminotransferase,” and decreased hepatic TG content. …”

Table_1_Clinical pharmacist interventions in nutrition-and drug-related problems in critically ill patients with renal dysfunction: a non-randomized controlled study.DOCX by Betül Özgan (19945353)

“…Their collaboration with healthcare professionals significantly reduced both DRPs and NRPs.</p>…”

Supplementary Material for: Hemispherotomy for Drug-Resistant Epilepsy in a Low-resource Setting: Surgical Outcomes and Quality of Life in 23 Children Treated in a Hybrid Program i... by figshare admin karger (2628495)

“…Patients with seizure freedom had significantly fewer preoperative seizures per day than patients with seizure recurrence. …”

Data Sheet 1_Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice.pdf by Cara J. Westmark (9302270)

“…Beta-diversity of the cecal microbiome was significantly altered as a function of the four test diets. …”

Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg by Ling Hu (374570)

“…Background<p>The pivotal responsibility of GABAergic interneurons is inhibitory neurotransmission; in this way, their significance lies in regulating the maintenance of excitation/inhibition (E/I) balance in cortical circuits. …”

<i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation by jin guan (21792620)

“…<p dir="ltr">Invasive Salmonella Typhimurium (<i>S</i>. Typhimurium) causes lethal bloodstream infections (BSI), yet its molecular mechanisms remain unclear. …”

Image 1_The gut microbiome: a vital link to hyperuricemia, gout and acute flares?.pdf by Wei Wang (17594)

“…Furthermore, the gut microbiota of gout patients also exhibited significantly reduced microbial diversity compared with asymptomatic hyperuricemic patients, characterized by decreased richness of the genera Dialister, Ruminococcus, and Faecalibacterium. …”

Data Sheet 1_Nonlinear responses of ecosystem carbon fluxes to precipitation change in a semiarid grassland.doc by Hua Chai (280388)

“…We found that both decreased and increased precipitation significantly altered the GEP (from –26% to 14%), but only decreased precipitation significantly reduced the ER and NEE (from 1% to 31%), relative to their values during natural precipitation. …”

Table S13 from Functional Mapping of Epigenomic Regulators Uncovers Coordinated Tumor Suppression by the HBO1 and MLL1 Complexes by Yuning J. Tang (22761599)

“…<p>Categories and percent frequency of significantly decreased chromatin accessibility regions</p>…”

Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing by Noora Kantola (14263490)

“…On the contrary, increased snow depth decreased C source strength inside the exclusion offsetting the difference between reindeer grazing treatments. …”

Data Sheet 1_Effects of nitrogen application amount on nitrogen distribution and photosynthesis in tea leaves.pdf by Kai Li (205203)

“…Additionally, nitrogen content in the structural system increased slowly, whereas that in the storage system rose significantly. With increasing nitrogen levels, the distribution ratio of leaf nitrogen in the carboxylation and electron transport systems initially increased and then decreased; in the structural system, it first decreased and subsequently stabilized, while in the storage system, it gradually increased. …”

Table 1_Metabolic changes after growth hormone treatment in children with growth hormone deficiency and small for gestational age: LG observational study.docx by Sujin Kim (225506)

“…ALT levels significantly decreased in all follow-up years in the GHD group. …”

Data Sheet 1_Succinic acid improves crop chemical components by regulating soil chemical properties, microbes and metabolites.docx by Dian-long Li (22465567)

“…The relative abundance of Proteobacteria in the bacterial community was significantly decreased, while that of Chloroflexi was significantly increased. …”

<b>Supplementary Fig. 1</b> by Richard Babicz (18865600)

“…Erlotinib treatment significantly decreased phospho-ERK levels at both concentrations (figure 1, left). …”

<b>Supplementary Figure 1</b> by Richard Babicz (18865600)

“…Erlotinib treatment significantly decreased phospho-ERK levels at both concentrations (figure 1, left). …”

Table 1_Spatial yield gains in empty-row optimized rice–crab co-culture are linked to nifH-driven nitrogen compensation in border rows.docx by Tiexin Yang (21423032)

“…</p>Results<p>Our results showed that although ERC-12 increased per-plant yield via marginal effects in the boundary zone (PB), total yield decreased by 4.06%-5.20% compared to CK, primarily due to yield losses in the intermediate zone (PM) and empty rows. …”

DataSheet1_Dectin-1 participates in the immune-inflammatory response to mouse Aspergillus fumigatus keratitis by modulating macrophage polarization.doc by Liu Guibo (19857723)

“…The number of macrophages in the corneal stroma of mice in the curdlan pretreatment group increased significantly compared with the PBS group, while in the laminaran pretreatment group this number decreased significantly. 5. …”