Knockdown of fatty acid binding protein 3 attenuates cerebral Ischemia-reperfusion injury <i>via</i> inhibiting neuronal apoptosis in mice by Jin-Jin Tian (22046330)

“…<p>Background: Stroke remains a leading cause of death and disability worldwide, with ischemic stroke accounting for approximately 87% of cases. …”

Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx by Hailiang Li (740080)

“…Meanwhile, NADPH+ production and G6PDH enzyme activity significantly decreased. Further study validated that metformin inhibited the cell growth of GBM cell lines through up-regulating PER2 and inhibited SIRT2/G6PD signaling pathway, enhancing radiotherapy(RT) sensitivity. …”

Image 1_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Background<p>Type 1 Diabetes (T1D) is caused by a combination of genetic and environmental factors that trigger autoimmune-mediated destruction of pancreatic β-cells. …”

Table 1_Genetic diversity and antibiotic resistance of Mycobacterium bovis in bovines in the Delta area of Egypt.docx by Mohamed Sabry A. Elsayed (22235200)

“…Introduction<p>Mycobacterium bovis (M. bovis) causes significant financial harm to the cattle industry through decreased productivity and trade limitations, while also posing a risk to human health through zoonotic transmission, which is primarily from unpasteurized milk or close animal contact.…”

Image 3_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Background<p>Type 1 Diabetes (T1D) is caused by a combination of genetic and environmental factors that trigger autoimmune-mediated destruction of pancreatic β-cells. …”

Image 4_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tif by Matthew C. Austin (20633168)

“…Background<p>Type 1 Diabetes (T1D) is caused by a combination of genetic and environmental factors that trigger autoimmune-mediated destruction of pancreatic β-cells. …”

Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Background<p>Type 1 Diabetes (T1D) is caused by a combination of genetic and environmental factors that trigger autoimmune-mediated destruction of pancreatic β-cells. …”

Supplementary Material for: Head positioning for stroke blood flow augmentation assisting reperfusion therapies (HEAD-START) study by figshare admin karger (2628495)

“…Trendelenburg positioning was maintained for 24h if lesion volume significantly decreased (≥5mL) and stroke reperfusion was suboptimal or undetermined. …”

Data Sheet 1_α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT–FOXO1–CD36 pathway.pdf by Xue Bai (129175)

“…Introduction<p>Diabetic cardiomyopathy (DCM), a cardiac complication of diabetes, is the main cause of the high prevalence of heart failure and associated mortality in diabetic patients. …”

Postoperative complications and mortality [n(%)]. by Qingwen Cao (22439195)

“…The proportion of patients with American Society of Anesthesiologists (ASA) ≥ III, Nottingham hip fracture score (NHFS) ≥ 5 and preoperative activity tolerance < 4 metabolic equivalents (METs) increased sequentially (<i><i>P</i> </i>< 0.001), across the YO, MO, and OO groups, whereas the proportion of those with three or more internal medicine comorbidities sequentially decreased (<i><i>P</i> </i>< 0.001). All three groups were primarily injured by falls and the older the age, the higher the proportion of injuries caused by falls (<i><i>P</i> </i>= 0.006). …”

Information of surgery and anesthesia [n(%)]. by Qingwen Cao (22439195)

“…The proportion of patients with American Society of Anesthesiologists (ASA) ≥ III, Nottingham hip fracture score (NHFS) ≥ 5 and preoperative activity tolerance < 4 metabolic equivalents (METs) increased sequentially (<i><i>P</i> </i>< 0.001), across the YO, MO, and OO groups, whereas the proportion of those with three or more internal medicine comorbidities sequentially decreased (<i><i>P</i> </i>< 0.001). All three groups were primarily injured by falls and the older the age, the higher the proportion of injuries caused by falls (<i><i>P</i> </i>= 0.006). …”

Raw data. by Qingwen Cao (22439195)

“…The proportion of patients with American Society of Anesthesiologists (ASA) ≥ III, Nottingham hip fracture score (NHFS) ≥ 5 and preoperative activity tolerance < 4 metabolic equivalents (METs) increased sequentially (<i><i>P</i> </i>< 0.001), across the YO, MO, and OO groups, whereas the proportion of those with three or more internal medicine comorbidities sequentially decreased (<i><i>P</i> </i>< 0.001). All three groups were primarily injured by falls and the older the age, the higher the proportion of injuries caused by falls (<i><i>P</i> </i>= 0.006). …”

Data Sheet 1_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

Data Sheet 2_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

DataSheet_1_Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile.docx by Rocío Rubio (513839)

“…Our results show that SARS-CoV-2 infection during the third trimester of pregnancy induces a robust antibody and cytokine response at delivery and causes a significant reduction of the SARS-CoV-2-specific IgGs transplacental transfer, with a stronger negative effect when the infection is closer to delivery.…”

Replication of the main behavioral patterns of actions and judgments in Experiment 3. by Claire Lugrin (21156528)

“…Trials between those two lines have equal efficiency for selfish and prosocial actions (pB = b). selfish action increases with stakes (bonus) and decreases with potential harm caused (pB). Judgments become more lenient (towards appropriate) as stakes (bonus) increase and stricter (towards inappropriate) as the harm caused increases (pB). …”

Changes in functional connectivity between NREM and REM – comparison of in vivo experimental and in silico modeling data. by Michael Satchell (21560808)

“…Red indicates pairs with decreasing functional connectivity from NREM to REM, black indicates pairs with increasing functional connectivity from NREM to REM. …”

Ca²⁺ homeostasis and the corpuscles of Stannius regulate sensory gating. by Susannah S. Schloss (21238775)

“…<b>(A)</b> Exposure to high (10 mM) Ca²⁺ caused a slight but significant increase in whole-body Ca²⁺ levels, compared to normal 0.33 mM Ca²⁺ (*<i>p</i> = 0.024). …”

Table 1_Revised Peck’s formula for estimating pipeline’s settlement under the coupling effect of tunnelling and vehicle load.xlsx by Shu Peng (642390)

“…The results reveal that the settlement of soil and pipeline caused by tunnelling decreases with decreasing burial depth; the dynamic settlement of the sewage pipe and ground surface is decreasing rapidly as the burial depth increases. …”

Data Sheet 1_Soil microbiome dysbiosis and rhizosphere metabolic dysfunction drive continuous cropping obstacles of Codonopsis tangshen.docx by Dabing Xu (18961138)

“…However, their abundance decreased significantly under continuous cropping, ultimately disrupting soil carbon cycling. …”