يعرض 17,961 - 17,980 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant challenge decrease ))', وقت الاستعلام: 0.47s تنقيح النتائج
  1. 17961

    Data Sheet 2_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.docx حسب Renshengjie Zhao (22459771)

    منشور في 2025
    "…However, our previous studies revealed significant upregulation of NRIR in peri-implantitis, suggesting its potential role in peri-implantitis. …"
  2. 17962

    Model index comparison. حسب Tingting Cui (564531)

    منشور في 2024
    "…The factors within the Park attributes (G1) and the park’s social media level (G4) showed a two-way interaction strength increase. (4)The coefficients of influence of impact factors on the space heterogeneity of vacation park vitality exhibit significant variation. The positive indicators have a spatial distribution that decreases from the northwest to the southeast, with the old city district having higher coefficients than the new city district. …"
  3. 17963

    Data Sheet 1_Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systemat... حسب Yuhua Jiang (10300159)

    منشور في 2025
    "…PSCK9 inhibitors and potent statins significantly reduced LDL-C levels from baseline vs. placebo regardless of background therapy. …"
  4. 17964

     'Plan-B':  Impact of changes in the global funding landscape for Hepatitis B clinical and research programmes حسب marion delphin (13249479)

    منشور في 2025
    "…One-third of respondents reported already experiencing significant impact from funding changes, while over two-thirds expressed high concerns about future effects. …"
  5. 17965

    Datasheet1_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of dis... حسب Juan Tang (437969)

    منشور في 2024
    "…Despite global declines in IHD incidence over the last three decades, decreasing trends in incidence have slowed and, in some countries, flattened. …"
  6. 17966

    Table 1_Impact of short-term (24 h) blood pressure variability on 30-days clinical outcomes of acute strokes at two tertiary hospitals in Dar-es-Salaam.docx حسب Ayubu Eliesikia Mashambo (22596824)

    منشور في 2025
    "…Functional outcomes improved significantly by day 30: the Barthel Index increased, and mRS scores decreased. …"
  7. 17967

    Image 1_Effect of midwife-led continuity of care combined with individualized breast management on postpartum recovery and lactation function in women undergoing cesarean section.t... حسب Hua Cai (15034)

    منشور في 2025
    "…Although the incidence of pelvic floor dysfunction showed a decreasing trend in the intervention group, this difference was not statistically significant (p > 0.05). …"
  8. 17968

    Data Sheet 4_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf حسب Erman Wu (19021269)

    منشور في 2025
    "…Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …"
  9. 17969

    Table 1_The effect of Traumeel LT ad us. vet. on the perioperative inflammatory response after castration of stallions: a prospective, randomized, double-blinded study.docx حسب Julia Laves (19779357)

    منشور في 2024
    "…All stallions had the highest pain summary score 8 hours after surgery, with decreasing values thereafter. The pain scores were not statistically different at any time point. …"
  10. 17970
  11. 17971

    Data Sheet 1_MIKC-type MADS-box transcription factor OsMADS31 positively regulates salinity tolerance in rice.pdf حسب Xiaolin Yin (359202)

    منشور في 2025
    "…Conversely, compared with WT plants, 3,3’-diaminobenzidine (DAB) and nitroblue tetrazolium (NBT) staining intensities as well as malondialdehyde (MDA) content were significantly higher in osmads31 mutants and significantly lower in OE lines. …"
  12. 17972

    Summertime bedroom overheating in un-airconditioned UK urban apartments: factors influencing subjective and objective sleep outcomes حسب Iuliana Hartescu (1249374)

    منشور في 2025
    "…</p><p dir="ltr">Results: Night-time (22.00-07.00) bedroom temperatures rose significantly during HN (range BL = 17.5-26.4°C; HN = 22.0-29.3°C, p<0.001) with thermal comfort (p<0.001), ‘restfulness’ (p<0.001) and TST (p<0.05) significantly decreasing, while heat-related sleep disturbance significantly increased (p<0.001). …"
  13. 17973

    Data Sheet 1_Impact of mini-dose dexmedetomidine supplemented analgesia on sleep structure in patients at high risk of obstructive sleep apnea: a pilot trial.docx حسب Pei Sun (115160)

    منشور في 2024
    "…Other sleep structure and sleep-respiratory parameters did not differ significantly between the two groups. Subjective sleep quality was slightly improved with dexmedetomidine on the night of surgery, but not statistically significant (median difference, 6; 95% CI, 0 to 13; p = 0.060). …"
  14. 17974

    Table 1_Protocatechuic aldehyde ameliorates high glucose-induced podocyte injury by attenuating inflammation, oxidative stress, and apoptosis via suppression of endoplasmic reticul... حسب Yishu Wang (845334)

    منشور في 2025
    "…PCA significantly reduced the secretion of inflammatory cytokines (TNF-α, IL-1β, IL-6), restored the activities of SOD and GSH-Px, decreased MDA content, and downregulated the expression of Cox-2, iNOS, Nox2, and Nox4 proteins, thereby suppressing HG-induced podocyte inflammation and oxidative stress. …"
  15. 17975

    Image 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff حسب Peerapon Kiatkittikul (22801874)

    منشور في 2025
    "…Healthy control also showed globally increased [<sup>18</sup>F]SMBT-1 uptake. There was no significant correlation between the degree of [<sup>18</sup>F]FDOPA uptake and [<sup>18</sup>F]SMBT-1 uptake in any brain region.…"
  16. 17976

    Internal states adjust the Brp compartmental heterogeneity through octopamine. حسب Hongyang Wu (8856740)

    منشور في 2025
    "…*<i>P</i> < 0.05 and ns = not significant. The data underlying this Figure can be found in S1 Data.…"
  17. 17977

    Data Sheet 2_Comparison of percutaneous vs. cutdown access for endovascular aortic repair in the treatment of type B aortic dissection: a meta-analysis.pdf حسب Zhongyou Liang (22617608)

    منشور في 2025
    "…No statistically significant differences were observed between the two groups concerning estimated blood loss, ICU admissions, hematoma, acute kidney injury, lower extremity revascularization, ischemic colitis, and deep venous thrombosis.…"
  18. 17978

    Evolutionarily conserved and functionally important amino acids in Artemis. حسب Ziwen Huang (17562948)

    منشور في 2025
    "…<i>P</i> values were analyzed with Student <i>t</i> test. ns, not significant.</p>…"
  19. 17979

    Figure 5 from Functional Profiling of p53 and RB Cell Cycle Regulatory Proficiency Suggests Mechanism-Driven Molecular Stratification in Endometrial Carcinoma حسب Zelei Yang (18491142)

    منشور في 2025
    "…<p>Aurora kinase B inhibitor sensitive endometrial carcinoma cells show more rapidly decreasing percentages of mitotic cells than resistant models in the setting of nocodazole-induced microtubule instability. …"
  20. 17980

    FLEXI interactions with RNA-binding proteins. حسب Jun Yao (9646)

    منشور في 2024
    "…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …"