Showing 1,241 - 1,260 results of 2,040 for search '(( significant decrease decrease ) OR ( significant challenge decrease ))~', query time: 0.39s Refine Results
  1. 1241
  2. 1242

    Image1_The fruit fly Drosophila melanogaster as a screening model for antiseizure medications.JPEG by Florian P. Fischer (14457072)

    Published 2024
    “…Despite numerous newly marketed ASMs, the proportion of drug-resistant people with epilepsy has not significantly decreased over the years. Therefore, novel and innovative seizure models for preclinical drug screening are highly desirable. …”
  3. 1243

    Data_Sheet_1_Investigating the impact of mental rehearsal on prefrontal and motor cortical haemodynamic responses in surgeons using optical neuroimaging.docx by Hemel N. Modi (19919895)

    Published 2024
    “…Mean objective performance score was significantly higher following MR compared with TR (p = 0.043).…”
  4. 1244

    Data Sheet 1_Clinical predictors and concomitant antiseizure medications effects on seizure control in relation to plasma cenobamate concentration: a multicenter retrospective stud... by Francesca Felicia Operto (12509263)

    Published 2025
    “…Its non-linear pharmacokinetics and strong modulation of cytochrome P450 enzymes may significantly affect the metabolism of co-administered ASMs, posing important challenges for polytherapy management. …”
  5. 1245

    <b>Optimizing Viable Bacteria Detection in Ballast Tank Sediments: Addressing PCR Inhibitors and Relic DNA</b> by 1 Anonymous (21812990)

    Published 2025
    “…This study tackles two key challenges in viable microorganism monitoring in ballast tank sediments: interference from PCR inhibitors and the persistence of relic DNA. …”
  6. 1246

    Systematic review of evidence for the impact and effectiveness of the 1-3-7 strategy for malaria elimination by Richard J. Maude (9416228)

    Published 2025
    “…However, achieving this nationally and maintaining compliance, especially at borders with malaria-affected countries, poses significant challenges.</p>…”
  7. 1247

    Table 3_A scoping review of the feasibility, usability, and efficacy of digital interventions in older adults concerning physical activity and/or exercise.docx by Ethan C. J. Berry (21074345)

    Published 2025
    “…Background:<p>The global population is aging, leading to significant health challenges among older adults, such as reduced muscle mass, increased risks of dementias, and chronic diseases. …”
  8. 1248

    Table 1_A scoping review of the feasibility, usability, and efficacy of digital interventions in older adults concerning physical activity and/or exercise.xlsx by Ethan C. J. Berry (21074345)

    Published 2025
    “…Background:<p>The global population is aging, leading to significant health challenges among older adults, such as reduced muscle mass, increased risks of dementias, and chronic diseases. …”
  9. 1249

    Table 1_Cutaneous sensory symptoms and emotional regulation in non-clinical healthy students: a near-infrared spectroscopy study.docx by Sachiyo Ozawa (22289089)

    Published 2025
    “…Only those with lower symptoms experienced a decrease in unpleasant emotions. Furthermore, participants with higher cutaneous symptoms exhibited medial prefrontal cortex activation during distraction, with no significant activation differences in the lateral prefrontal cortex.…”
  10. 1250

    Table 2_A scoping review of the feasibility, usability, and efficacy of digital interventions in older adults concerning physical activity and/or exercise.docx by Ethan C. J. Berry (21074345)

    Published 2025
    “…Background:<p>The global population is aging, leading to significant health challenges among older adults, such as reduced muscle mass, increased risks of dementias, and chronic diseases. …”
  11. 1251

    Data Sheet 1_Impact of the SARS-COV-2 pandemic on access to health services in Angola: a focus on diagnosis and treatment services for tuberculosis.docx by Susanna Caminada (16789893)

    Published 2025
    “…</p>Results<p>There was a significant decline in access to TB services during the pandemic, with a substantial decrease in reported cases (−15.5% in 2020; −18.3% in 2021) and treatment rate (from 86% in 2019 to 68% in 2020), an increase in multidrug-resistant-TB (from 0.2% in 2018 to 2.1% in 2022) and TB/HIV co-infections (from 6% in 2018 to 8.8% in 2021). …”
  12. 1252

    Factors contributing to poststroke depression (Gurley Nettles, 2024) by Tiffany C. Gurley Nettles (19787799)

    Published 2024
    “…With an increasing number of stroke survivors returning to the community, informal care provided by family members will continue to rise. Many of the challenges faced by stroke survivors with poststroke depression (PSD) and by family caregivers (FCGs) have a significant impact on the relationship itself. …”
  13. 1253

    Data Sheet 1_From demyelination to neurodegeneration in multiple sclerosis: reassessing the role of visual evoked potential P100-N145 amplitudes: a missing piece of the puzzle?.zip by Nurhan Kaya Tutar (22327474)

    Published 2025
    “…</p>Results<p>EDSS progression was observed in 17.8% of patients. A longitudinal decrease in P100–N145 amplitude from baseline to follow-up was significantly associated with EDSS progression (OR: 1.511, 95% CI, p < 0.001). …”
  14. 1254

    Video 1_Real-time segmentation and phenotypic analysis of rice seeds using YOLOv11-LA and RiceLCNN.mp4 by Dejia Zhang (18526510)

    Published 2025
    “…These modifications not only improve detection accuracy but also significantly reduce the number of parameters by 63.2% and decrease computational complexity by 51.6%. …”
  15. 1255

    Video 2_Real-time segmentation and phenotypic analysis of rice seeds using YOLOv11-LA and RiceLCNN.mp4 by Dejia Zhang (18526510)

    Published 2025
    “…These modifications not only improve detection accuracy but also significantly reduce the number of parameters by 63.2% and decrease computational complexity by 51.6%. …”
  16. 1256

    Table 1_Effectiveness of conversational script optimization by intelligent consultation robots on daily work efficiency in vaccination clinics.docx by Bei Zhou (5219792)

    Published 2025
    “…Introduction<p>Vaccines are essential for reducing infectious disease incidence, but challenges like public awareness and healthcare workloads persist. …”
  17. 1257

    Table 3_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

    Published 2025
    “…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”
  18. 1258

    Table 7_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

    Published 2025
    “…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”
  19. 1259

    Image 1_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.jpg by Joanna Palade (17712960)

    Published 2025
    “…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”
  20. 1260

    Table 8_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

    Published 2025
    “…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”