يعرض 1,461 - 1,480 نتائج من 2,040 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant challenge decrease ))~', وقت الاستعلام: 0.24s تنقيح النتائج
  1. 1461

    Table 1_Decadal trends and regional disparities in tuberculosis burden: a comprehensive analysis of global, African, and Southeast Asian data from the GBD 1990–2021.docx حسب Shiwei Xie (3617159)

    منشور في 2025
    "…The annual percentage change (APC) was calculated to assess the significance of temporal trends.</p>Results<p>From 1990 to 2021, global age-standardized rates of TB declined markedly, with ASIR decreasing from 173.0 to 103.0 per 100,000, ASMR from 40.0 to 14.0, and ASDR from 1,650.6 to 580.3. …"
  2. 1462

    Table 2_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xls حسب Ahmet Alptekin (14937405)

    منشور في 2025
    "…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…"
  3. 1463

    Data Sheet 1_Analysis of temporal and spatial changes in the global burden of hypertensive heart disease based on data from the Global Burden of Disease study database and future p... حسب Guoliang Gao (2910503)

    منشور في 2025
    "…According to the APC model, the worldwide incidence of hypertensive heart disease is expected to increase from 2022 to 2046, with further decreases in deaths and DALYs.</p>Conclusions<p>This study systematically reveals the increasing trend in the incidence of hypertensive heart disease globally between 1990 and 2021 and confirms the significant impact of sex and socioeconomic development level on its burden. …"
  4. 1464

    Table 1_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xls حسب Ahmet Alptekin (14937405)

    منشور في 2025
    "…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…"
  5. 1465

    Table 5_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xlsx حسب Ahmet Alptekin (14937405)

    منشور في 2025
    "…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…"
  6. 1466

    Image 3_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg حسب Dylan Krajewski (5881880)

    منشور في 2025
    "…IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …"
  7. 1467

    Image 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif حسب Thibaud Dauphin (21196820)

    منشور في 2025
    "…Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells.…"
  8. 1468

    DataSheet3_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx حسب Yiyi Zuo (19945293)

    منشور في 2024
    "…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …"
  9. 1469

    Image8_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellula... حسب Huipeng Fang (12587509)

    منشور في 2024
    "…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …"
  10. 1470

    Image 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif حسب Thibaud Dauphin (21196820)

    منشور في 2025
    "…Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells.…"
  11. 1471

    Image9_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellula... حسب Huipeng Fang (12587509)

    منشور في 2024
    "…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …"
  12. 1472

    Data Sheet 1_Synergistic effects of Candida albicans and Porphyromonas gingivalis biofilms on epithelial barrier function in a 3D aspiration pneumonia model.pdf حسب Ewelina Wronowska (20555480)

    منشور في 2025
    "…Introduction<p>Polymicrobial infections involving Candida albicans and Porphyromonas gingivalis represent a significant challenge in maintaining epithelial barrier integrity. …"
  13. 1473

    Image4_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellula... حسب Huipeng Fang (12587509)

    منشور في 2024
    "…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …"
  14. 1474

    Image11_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellul... حسب Huipeng Fang (12587509)

    منشور في 2024
    "…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …"
  15. 1475

    Data Sheet 1_Association of advanced lung cancer inflammation index with all-cause and cardiovascular mortality in US patients with asthma.pdf حسب Jiatao Li (10033795)

    منشور في 2025
    "…Background<p>Asthma poses a significant global health challenge, representing a chronic respiratory disorder marked by airway inflammation. …"
  16. 1476

    DataSheet2_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx حسب Yiyi Zuo (19945293)

    منشور في 2024
    "…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …"
  17. 1477

    Data_Sheet_1_Depression and health literacy among adolescents and adults in Germany: findings from two representative samples.pdf حسب Lars König (3440474)

    منشور في 2024
    "…Introduction<p>Depressive disorders constitute a significant public health challenge. Health literacy might be an important factor to consider in prevention strategies for depressive disorders, which is why this study aimed at exploring the association between depressive symptom levels and severity and health literacy, along with additional sociodemographic factors.…"
  18. 1478

    Image 1_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg حسب Dylan Krajewski (5881880)

    منشور في 2025
    "…IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …"
  19. 1479

    Data Sheet 1_Effects of plant extracts on patients with heart failure: a network meta-analysis of randomized controlled trials.pdf حسب Jieyin Deng (22563188)

    منشور في 2025
    "…Ethnopharmacological relevance<p>Heart failure (HF) is a major global health challenge. Traditional therapies have limitations, while recent studies highlight plant extracts’ potential due to their medicinal properties and milder side effects.…"
  20. 1480

    Image 2_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg حسب Dylan Krajewski (5881880)

    منشور في 2025
    "…IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …"