بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
challenge » challenges (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
challenge » challenges (توسيع البحث)
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1621
Data Sheet 4_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip
منشور في 2025"…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"
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1622
Data Sheet 5_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip
منشور في 2025"…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"
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1623
Optimizing Irradiation Dose for <i>Drosophila melanogaster</i> Males to Enhance Heterospecific Sterile Insect Technique Against <i>Drosophila suzukii</i>
منشور في 2025"…<p dir="ltr">The spotted-wing drosophila (<i>Drosophila suzukii</i>), a highly invasive agricultural pest, poses significant challenges to fruit production worldwide. …"
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1624
Supplementary file 1_Feasibility of repetitive transcranial magnetic stimulation on non-motor symptoms of spinocerebellar ataxia type 3: a secondary analysis of a randomized clinic...
منشور في 2025"…</p>Results<p>The results disclosed significant time effects for all the outcomes with post hoc comparisons showing differences of baseline and post-treatment evaluation, with decreases for PSQI, AIS, HARS, and HDRS as well as increase for MMSE and MoCA. …"
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1625
Data_Sheet_1_A novel chimeric endolysin Cly2v shows potential in treating streptococci-induced bovine mastitis and systemic infections.docx
منشور في 2024"…Additionally, in a systemic infection model, treatment with Cly2v (400 μg/mouse) provided protection rates of up to 100 and 78% against S. agalactiae ATCC13813 infections when challenged for 1 h and 3 h, respectively. Furthermore, a significant reduction in bacterial loads was observed in the blood and organs compared to the PBS group. …"
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1626
Table 1_Gut-to-tumor translocation of multidrug-resistant Klebsiella pneumoniae shapes the microbiome and chemoresistance in pancreatic cancer.docx
منشور في 2025"…Nevertheless, the complexity of gut microbiota composition poses significant challenges in identifying definitive clinical biomarkers for PC.…"
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1627
Table 1_The role of eosinophils and their activation state in hypereosinophilia-associated heart disease.pdf
منشور في 2025"…</p>Results<p>Mice challenged with the myocarditic and control peptide had peripheral blood leukocytosis, but only those challenged with the myocarditic peptide had heart inflammation. …"
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1628
Presentation 1_The role of eosinophils and their activation state in hypereosinophilia-associated heart disease.pdf
منشور في 2025"…</p>Results<p>Mice challenged with the myocarditic and control peptide had peripheral blood leukocytosis, but only those challenged with the myocarditic peptide had heart inflammation. …"
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1629
Table 2_The role of eosinophils and their activation state in hypereosinophilia-associated heart disease.xlsx
منشور في 2025"…</p>Results<p>Mice challenged with the myocarditic and control peptide had peripheral blood leukocytosis, but only those challenged with the myocarditic peptide had heart inflammation. …"
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1630
All source data of the paper “The mimicking and synergistic effects of magnetic fields on caloric restriction”
منشور في 2024"…Nonetheless, maintaining strict long-term compliance to CR and overcome its the metabolic adaptation have proven to be significant challenges. In this study, we discovered that combining CR with magnetic fields (MFs), a straightforward physical intervention, can increase the ATP production and mitochondrial respiration in liver cells. …"
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1631
Data Sheet 1_Virus-like particles containing the extracellular domain of G protein in combination with a CTL peptide of M2 elicit protection against respiratory syncytial virus inf...
منشور في 2025"…Post-RSV challenge, mice vaccinated with G<sub>ECD</sub>/M2<sub>82-90</sub>-VLPs exhibited a substantially increased proportion of CD25<sup>+</sup>FoxP3<sup>+</sup> Treg cells and a decreased percentage of Th17 cells in the lungs. …"
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1632
Impact of Pilates training on gait performance in individuals with unilateral transtibial amputation
منشور في 2025"…Walking speed increased significantly for SSWS (<i>p</i> < 0.001) and FWS (<i>p</i> = 0.002). …"
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1633
Table 6_How efficient are specialized public health services in China? A data envelopment analysis and geographically weighted regression approach.docx
منشور في 2025"…Background<p>The Chinese public health system is grappling with escalating demands, which stemmed from the challenges of preventing chronic and infectious diseases, as well as the aging population. …"
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1634
Table 1_MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.xlsx
منشور في 2025"…The complex pathogenesis and therapeutic resistance of liver hepatocellular carcinoma (LIHC) present significant clinical challenges. This study investigates MFSD12’s potential involvement in LIHC progression.…"
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1635
Data Sheet 1_MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.zip
منشور في 2025"…The complex pathogenesis and therapeutic resistance of liver hepatocellular carcinoma (LIHC) present significant clinical challenges. This study investigates MFSD12’s potential involvement in LIHC progression.…"
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1636
Table 2_How efficient are specialized public health services in China? A data envelopment analysis and geographically weighted regression approach.docx
منشور في 2025"…Background<p>The Chinese public health system is grappling with escalating demands, which stemmed from the challenges of preventing chronic and infectious diseases, as well as the aging population. …"
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1637
Data Sheet 1_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip
منشور في 2025"…</p>Discussion<p>The global burden of IBD in children and adolescents is characterized by significant regional disparities, with VEO-IBD presenting unique challenges. …"
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1638
Image 6_MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.jpeg
منشور في 2025"…The complex pathogenesis and therapeutic resistance of liver hepatocellular carcinoma (LIHC) present significant clinical challenges. This study investigates MFSD12’s potential involvement in LIHC progression.…"
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1639
Video 2_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4
منشور في 2025"…Traditional OA management consist of non-steroidal anti-inflammatory drugs and remains challenging because of significant side effects, thus there is an urgent need for new effective and safe therapeutics for OA.…"
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1640
Data Sheet 3_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip
منشور في 2025"…</p>Discussion<p>The global burden of IBD in children and adolescents is characterized by significant regional disparities, with VEO-IBD presenting unique challenges. …"