يعرض 1,621 - 1,640 نتائج من 2,040 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant challenge decrease ))~', وقت الاستعلام: 0.46s تنقيح النتائج
  1. 1621

    Data Sheet 4_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip حسب Haiyan Liao (6100043)

    منشور في 2025
    "…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"
  2. 1622

    Data Sheet 5_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip حسب Haiyan Liao (6100043)

    منشور في 2025
    "…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"
  3. 1623

    Optimizing Irradiation Dose for <i>Drosophila melanogaster</i> Males to Enhance Heterospecific Sterile Insect Technique Against <i>Drosophila suzukii</i> حسب Flavia Cerasti (21075827)

    منشور في 2025
    "…<p dir="ltr">The spotted-wing drosophila (<i>Drosophila suzukii</i>), a highly invasive agricultural pest, poses significant challenges to fruit production worldwide. …"
  4. 1624

    Supplementary file 1_Feasibility of repetitive transcranial magnetic stimulation on non-motor symptoms of spinocerebellar ataxia type 3: a secondary analysis of a randomized clinic... حسب Hua Wu (2707)

    منشور في 2025
    "…</p>Results<p>The results disclosed significant time effects for all the outcomes with post hoc comparisons showing differences of baseline and post-treatment evaluation, with decreases for PSQI, AIS, HARS, and HDRS as well as increase for MMSE and MoCA. …"
  5. 1625

    Data_Sheet_1_A novel chimeric endolysin Cly2v shows potential in treating streptococci-induced bovine mastitis and systemic infections.docx حسب Shuang Wang (46453)

    منشور في 2024
    "…Additionally, in a systemic infection model, treatment with Cly2v (400 μg/mouse) provided protection rates of up to 100 and 78% against S. agalactiae ATCC13813 infections when challenged for 1 h and 3 h, respectively. Furthermore, a significant reduction in bacterial loads was observed in the blood and organs compared to the PBS group. …"
  6. 1626

    Table 1_Gut-to-tumor translocation of multidrug-resistant Klebsiella pneumoniae shapes the microbiome and chemoresistance in pancreatic cancer.docx حسب Lei Zhao (144153)

    منشور في 2025
    "…Nevertheless, the complexity of gut microbiota composition poses significant challenges in identifying definitive clinical biomarkers for PC.…"
  7. 1627

    Table 1_The role of eosinophils and their activation state in hypereosinophilia-associated heart disease.pdf حسب Usman Sunusi (22274329)

    منشور في 2025
    "…</p>Results<p>Mice challenged with the myocarditic and control peptide had peripheral blood leukocytosis, but only those challenged with the myocarditic peptide had heart inflammation. …"
  8. 1628

    Presentation 1_The role of eosinophils and their activation state in hypereosinophilia-associated heart disease.pdf حسب Usman Sunusi (22274329)

    منشور في 2025
    "…</p>Results<p>Mice challenged with the myocarditic and control peptide had peripheral blood leukocytosis, but only those challenged with the myocarditic peptide had heart inflammation. …"
  9. 1629

    Table 2_The role of eosinophils and their activation state in hypereosinophilia-associated heart disease.xlsx حسب Usman Sunusi (22274329)

    منشور في 2025
    "…</p>Results<p>Mice challenged with the myocarditic and control peptide had peripheral blood leukocytosis, but only those challenged with the myocarditic peptide had heart inflammation. …"
  10. 1630

    All source data of the paper “The mimicking and synergistic effects of magnetic fields on caloric restriction” حسب Xin Zhang (17292393)

    منشور في 2024
    "…Nonetheless, maintaining strict long-term compliance to CR and overcome its the metabolic adaptation have proven to be significant challenges. In this study, we discovered that combining CR with magnetic fields (MFs), a straightforward physical intervention, can increase the ATP production and mitochondrial respiration in liver cells. …"
  11. 1631

    Data Sheet 1_Virus-like particles containing the extracellular domain of G protein in combination with a CTL peptide of M2 elicit protection against respiratory syncytial virus inf... حسب Huan Qin (3511913)

    منشور في 2025
    "…Post-RSV challenge, mice vaccinated with G<sub>ECD</sub>/M2<sub>82-90</sub>-VLPs exhibited a substantially increased proportion of CD25<sup>+</sup>FoxP3<sup>+</sup> Treg cells and a decreased percentage of Th17 cells in the lungs. …"
  12. 1632

    Impact of Pilates training on gait performance in individuals with unilateral transtibial amputation حسب Janny Mirian Antonelli Tavares (22452771)

    منشور في 2025
    "…Walking speed increased significantly for SSWS (<i>p</i> < 0.001) and FWS (<i>p</i> = 0.002). …"
  13. 1633

    Table 6_How efficient are specialized public health services in China? A data envelopment analysis and geographically weighted regression approach.docx حسب Qian Bai (605328)

    منشور في 2025
    "…Background<p>The Chinese public health system is grappling with escalating demands, which stemmed from the challenges of preventing chronic and infectious diseases, as well as the aging population. …"
  14. 1634

    Table 1_MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.xlsx حسب Kai Sun (140584)

    منشور في 2025
    "…The complex pathogenesis and therapeutic resistance of liver hepatocellular carcinoma (LIHC) present significant clinical challenges. This study investigates MFSD12’s potential involvement in LIHC progression.…"
  15. 1635

    Data Sheet 1_MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.zip حسب Kai Sun (140584)

    منشور في 2025
    "…The complex pathogenesis and therapeutic resistance of liver hepatocellular carcinoma (LIHC) present significant clinical challenges. This study investigates MFSD12’s potential involvement in LIHC progression.…"
  16. 1636

    Table 2_How efficient are specialized public health services in China? A data envelopment analysis and geographically weighted regression approach.docx حسب Qian Bai (605328)

    منشور في 2025
    "…Background<p>The Chinese public health system is grappling with escalating demands, which stemmed from the challenges of preventing chronic and infectious diseases, as well as the aging population. …"
  17. 1637

    Data Sheet 1_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip حسب Hai-Qing Tan (22173514)

    منشور في 2025
    "…</p>Discussion<p>The global burden of IBD in children and adolescents is characterized by significant regional disparities, with VEO-IBD presenting unique challenges. …"
  18. 1638

    Image 6_MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.jpeg حسب Kai Sun (140584)

    منشور في 2025
    "…The complex pathogenesis and therapeutic resistance of liver hepatocellular carcinoma (LIHC) present significant clinical challenges. This study investigates MFSD12’s potential involvement in LIHC progression.…"
  19. 1639

    Video 2_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 حسب Vladimir Gabai (38129)

    منشور في 2025
    "…Traditional OA management consist of non-steroidal anti-inflammatory drugs and remains challenging because of significant side effects, thus there is an urgent need for new effective and safe therapeutics for OA.…"
  20. 1640

    Data Sheet 3_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip حسب Hai-Qing Tan (22173514)

    منشور في 2025
    "…</p>Discussion<p>The global burden of IBD in children and adolescents is characterized by significant regional disparities, with VEO-IBD presenting unique challenges. …"