يعرض 1,881 - 1,900 نتائج من 2,040 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant challenge decrease ))~', وقت الاستعلام: 0.31s تنقيح النتائج
  1. 1881

    Data Sheet 1_Integrating groundwater pumping data with regression-enhanced random forest models to improve groundwater monitoring and management in a coastal region.pdf حسب Jamie Kim (14893220)

    منشور في 2024
    "…Using the trained RERF model, we generated 90 m spatial resolution WTD anomaly maps for New Jersey for January and July 2015, showing areas of increasing and decreasing WTD. We then inverted the RERF model to predict GWP using WTD anomalies, land cover, and a cross metric as additional inputs. …"
  2. 1882

    Image 2_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.jpeg حسب Amy Fagan (17678004)

    منشور في 2025
    "…</p>Methods<p>In the current study, we studied male and female mice with conditional loss of Bdnf in airway club cells and challenged them intranasally with saline (vehicle control) or interleukin 13 (IL-13) for 4 days. …"
  3. 1883

    Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca... حسب Jingshuang Song (11340138)

    منشور في 2024
    "…While some targeted therapies have been developed, there are still significant challenges in early diagnosis and treatment, highlighting the need to identify new biomarkers and therapeutic targets for breast cancer. …"
  4. 1884

    DataSheet1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... حسب Jingshuang Song (11340138)

    منشور في 2024
    "…While some targeted therapies have been developed, there are still significant challenges in early diagnosis and treatment, highlighting the need to identify new biomarkers and therapeutic targets for breast cancer. …"
  5. 1885

    Image 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff حسب Haoming Shen (3816988)

    منشور في 2025
    "…Background<p>Hepatocellular carcinoma (HCC) prognosis continues to be challenging due to tumor heterogeneity and dynamic immunosuppressive microenvironments. …"
  6. 1886

    Image 1_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.jpeg حسب Amy Fagan (17678004)

    منشور في 2025
    "…</p>Methods<p>In the current study, we studied male and female mice with conditional loss of Bdnf in airway club cells and challenged them intranasally with saline (vehicle control) or interleukin 13 (IL-13) for 4 days. …"
  7. 1887

    DataSheet2_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... حسب Jingshuang Song (11340138)

    منشور في 2024
    "…While some targeted therapies have been developed, there are still significant challenges in early diagnosis and treatment, highlighting the need to identify new biomarkers and therapeutic targets for breast cancer. …"
  8. 1888

    Data Sheet 1_Global impact of Occupational Noise-Induced Hearing Loss (ONIHL): trends, gender disparities, and future projections: 1990–2036.docx حسب Dandan Liu (303719)

    منشور في 2025
    "…Background<p>The burden of Occupational Noise-Induced Hearing Loss (ONIHL) is escalating globally, presenting significant challenges to society and healthcare systems. …"
  9. 1889

    Table 1_Screening of strawberry (Fragaria × ananassa Duch.) cultivars for drought tolerance based on physiological and biochemical responses under PEG-induced stress.docx حسب Şule Hilal Attar (22245970)

    منشور في 2025
    "…Photosynthetic Quantum Yield decreased by 7.9% and 12.2% across the two years. Conversely, LDMC increased by approximately 16% in both years, indicating morphological adaptation to water deficit. …"
  10. 1890

    Data Sheet 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.zip حسب Haoming Shen (3816988)

    منشور في 2025
    "…Background<p>Hepatocellular carcinoma (HCC) prognosis continues to be challenging due to tumor heterogeneity and dynamic immunosuppressive microenvironments. …"
  11. 1891

    Supplementary Material for: Leveraging NLP for Psychiatric Phenotyping from Spanish EHR: Enabling the Investigation of Transdiagnostic Symptom Profiles at Scale حسب figshare admin karger (2628495)

    منشور في 2025
    "…The COMBINED algorithm improved overall recall, without significantly decreasing precision (F1 of 0.78 and 0.77 on HOMO and CSJDM, respectively). …"
  12. 1892

    Table 1_Long-term oyster shell powder applications increase crop yields and control soil acidity and cadmium in red soil drylands.docx حسب Hao Li (31608)

    منشور في 2025
    "…While the short-term use of soil amendments has shown significant potential for mitigating these challenges, few studies have explored their long-term effects on acidified soils and heavy metal accumulation. …"
  13. 1893

    DataSheet1_Anaerobic membrane bioreactor (AnMBR) with external ultrafiltration membrane for the treatment of sugar beet vinasse.PDF حسب Beatriz Egerland Bueno (20143764)

    منشور في 2024
    "…<p>Vinasse, a by-product of ethanol production, is generated at significant rates. While rich in nutrients such as calcium, magnesium, and potassium, its high solids, organic matter, acidity, and sulfate content pose challenges when disposed directly on soil, necessitating treatment. …"
  14. 1894

    Data Sheet 1_The multivalent passive immune-protective vaccines of egg yolk immunoglobulin Y derived from live or inactivated Pseudomonas anguilliseptica against aquaculture pathog... حسب Pan Cui (5726669)

    منشور في 2025
    "…Furthermore, the structures of the kidney, spleen, and intestinal tissues were intact, and the expression of p53 and γH2A.X decreased in the kidney.</p>Conclusion<p>L-PA-IgY and I-PA-IgY can resist multiple bacterial infections and have immunoprotective effects with no significant differences. …"
  15. 1895

    Data Sheet 1_Yeast culture improves growth, antioxidant status, immunity, and gut microbiota homeostasis in preweaning Holstein calves.csv حسب Xueqiang Li (614522)

    منشور في 2025
    "…Serum levels of total antioxidant capacity (T-AOC), total superoxide dismutase (T-SOD), and glutathione peroxidase (GSH-Px) were significantly elevated, while malondialdehyde (MDA) content was significantly decreased (p < 0.05), indicating improved antioxidant status. …"
  16. 1896

    Table 1_Yeast culture improves growth, antioxidant status, immunity, and gut microbiota homeostasis in preweaning Holstein calves.docx حسب Xueqiang Li (614522)

    منشور في 2025
    "…Serum levels of total antioxidant capacity (T-AOC), total superoxide dismutase (T-SOD), and glutathione peroxidase (GSH-Px) were significantly elevated, while malondialdehyde (MDA) content was significantly decreased (p < 0.05), indicating improved antioxidant status. …"
  17. 1897

    Table_1_Effectiveness of sofosbuvir-based treatments for patients with hepatitis C virus genotype 6 infection: a real-world study from East China.DOC حسب Fan-Rong Jiang (20325720)

    منشور في 2024
    "…Background<p>Over the past decade, the proportion of hepatitis C virus (HCV) genotypes (GT) 1 and 2 has decreased in almost all regions of China, while GT 3 and 6 have emerged as new challenges. …"
  18. 1898

    Presentation 1_Efficacy of disitamab vedotin in non-small cell lung cancer with HER2 alterations: a multicenter, retrospective real-world study.pdf حسب Meiling Zhang (352540)

    منشور في 2024
    "…Background<p>Non-small cell lung cancer (NSCLC) with human epidermal growth factor receptor 2 (HER2) alterations poses a substantial treatment challenge. Current HER2-targeted therapies offer limited efficacy. …"
  19. 1899

    Image1_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif حسب Zi Yang (276531)

    منشور في 2024
    "…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …"
  20. 1900

    Table1_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.docx حسب Zi Yang (276531)

    منشور في 2024
    "…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …"