يعرض 18,721 - 18,740 نتائج من 23,503 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant challenges case ))', وقت الاستعلام: 0.32s تنقيح النتائج
  1. 18721

    Image 1_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif حسب Kun-Lin Lu (7256960)

    منشور في 2024
    "…Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…"
  2. 18722

    Table 3_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.docx حسب Zhengqing Yu (12641890)

    منشور في 2025
    "…Significant heterogeneity was detected in the pooled analysis and meta-regression analysis suggested that participants’ age and the prevalence of diabetes significantly accounted for the heterogeneity.…"
  3. 18723

    Table 1_Global, regional and national patterns and gender disparity of intraocular foreign bodies from 1990 to 2021.doc حسب Yi Shan (160293)

    منشور في 2025
    "…The age-standardized DALYs rates of males were significantly higher than those of females in all five SDI groups (p < 0.001) in 2021. …"
  4. 18724

    Data Sheet 1_Evaluating the therapeutic potential of BSA-reduced mussel-derived selenium nanoparticles to mitigate copper sulfate-induced hepatic damage and neurodegeneration in a... حسب Suganiya Umapathy (21383339)

    منشور في 2025
    "…Stabilized selenium nanoparticles reduced for 30 minutes (25 μg/ml) showed significant in vitro reactive oxygen species scavenging activity and improved in vivo antioxidant enzyme levels by decreasing lipid peroxidation and nitric oxide levels. …"
  5. 18725

    Data source. حسب Chao Ma (207385)

    منشور في 2025
    "…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …"
  6. 18726

    Data Sheet 1_Thalamic functional dysconnectivity in patients with left-hemisphere chronic capsular and pontine stroke.pdf حسب Jun Guo (85069)

    منشور في 2024
    "…</p>Results<p>The ipsilesional thalamus of CS patients had abnormally decreased FC with widespread cognitive-related areas while increased FC with visual- and somatic-motor areas. …"
  7. 18727

    Table 1_A two-sample bidirectional Mendelian randomization analysis between telomere length and hyperthyroidism.xlsx حسب Shiben Zhu (19159465)

    منشور في 2025
    "…Utilizing 139 genome-wide significant single nucleotide polymorphisms (SNPs) as instrumental variables (IVs) for TL, forward MR analyses indicated a negative causal effect of TL on hyperthyroidism. …"
  8. 18728

    Image 1_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.tif حسب Wenbing Zhang (152972)

    منشور في 2025
    "…A higher immune infiltration rate and lower IC50 values of anticancer drugs were significant in the high-risk group. In cellular experiments, Following MAN1B1 knockdown, in cell assays, the colony formation, migration, and invasion ability of HCT116 and HT29 cell lines decreased.…"
  9. 18729

    Image 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o... حسب Yangtian Jiao (21725018)

    منشور في 2025
    "…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …"
  10. 18730

    Data Sheet 1_Dysregulation of melatonin rhythm in Parkinson’s and Huntington’s disease: a systematic review and meta-analysis.docx حسب Reema Priyanka Suram (22399759)

    منشور في 2025
    "…In manifest HD, both amplitude [RoM = 0.92, 95% CI (0.81 to 1.02); p = 0.00] and acrophase [RoM = 0.92, 95% CI (0.07 to 1.78); p = 0.03] significantly decreased. PD patients with sleep disorders had significantly higher melatonin concentrations than the non-sleep disorder group, with a significant test group difference of p = 0.00. …"
  11. 18731

    Table 1_Inequalities and age-period-cohort effects of global and regional burden for interstitial lung disease and pulmonary sarcoidosis: based on Global Burden of Disease study 20... حسب Lei Zhang (38117)

    منشور في 2025
    "…Background<p>Interstitial lung disease (ILD) and pulmonary sarcoidosis pose significant disease burdens on a global scale.</p>Methods<p>The underlying data was derived from the Global Burden of Disease (GBD) 2021 database. …"
  12. 18732

    DataSheet5_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf حسب Yongming Du (807059)

    منشور في 2024
    "…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…"
  13. 18733

    Research Technology Flow Chart. حسب Chao Ma (207385)

    منشور في 2025
    "…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …"
  14. 18734

    Data Sheet 1_Andrographis paniculata restores gut health by suppressing inflammation and strengthening mucosal immunity.pdf حسب Vidushi Tyagi (14022240)

    منشور في 2025
    "…</p>Results<p>ApEtOH significantly downregulated the chemokines RANTES, MCP-1, and ENA-78, reducing the pro-inflammatory cytokines TNF-α and IL-6 in vitro. …"
  15. 18735

    Table 2_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.xlsx حسب Giuseppe G. F. Leite (18186056)

    منشور في 2024
    "…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …"
  16. 18736

    Image 2_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif حسب Kun-Lin Lu (7256960)

    منشور في 2024
    "…Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…"
  17. 18737

    Image1_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff حسب Alexandra Coello-Camba (6489533)

    منشور في 2024
    "…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …"
  18. 18738

    Data Sheet 1_Cultivar-specific responses of the citrus endophytic microbiome to Xanthomonas citri subsp. citri infection reveals Lysobacter as a key biocontrol taxon.xlsx حسب Yu Zhang (12946)

    منشور في 2025
    "…Conversely, fungal community richness decreased in both cultivars post-inoculation, with notable cultivar-specific changes in the relative abundance of key genera. …"
  19. 18739

    Presentation1_Pressure-tolerant survival mechanism of Schizophyllum commune 20R-7-F01 isolated from deep sediments 2 kilometers below the seafloor.pdf حسب Mengshi Zhao (20157978)

    منشور في 2024
    "…By assessing the cell viability, biomass, and cell wall thickness changes of strain 20-7-1 under different HHP conditions, we observed that, compared to 0.1 MPa, strain 20-7-1 exhibited slower growth rates and decreased cell viability at 15 MPa and 35 MPa, yet demonstrated significant pressure tolerance. …"
  20. 18740

    Aquaporin and red cell O2 permeability حسب S. Al-Samir (20965502)

    منشور في 2025
    "…We find that at 7°/10°C lack of AQP1 in the red cell membrane causes significant reductions of PO2, by 20% in human and by 37% in mouse red cells. …"