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significant challenges » significant challenge (Expand Search), significant changes (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
challenges case » challenges pose (Expand Search), challenges raised (Expand Search), challenges faced (Expand Search)
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19301
Supplementary file 1_Trend analysis and future projections of global burden of opioid use disorder (OUD) from 1990 to 2030.docx
Published 2025“…Objectives<p>Opioid Use Disorder (OUD) is a chronic medical crisis which represents significant public health challenge on global scale. …”
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19302
Supplementary file 2_Trend analysis and future projections of global burden of opioid use disorder (OUD) from 1990 to 2030.docx
Published 2025“…Objectives<p>Opioid Use Disorder (OUD) is a chronic medical crisis which represents significant public health challenge on global scale. …”
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19303
Table 1_Long-term trends in the burden of multiple myeloma in China: a Joinpoint regression and age-period-cohort analysis based on GBD 2021.docx
Published 2025“…</p>Results<p>It is estimated that in 2021, there were 17,250 new cases of MM in China, with 47,004 cases and 12,984 deaths. …”
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19304
CCDC66 localizes to the axoneme and regulates primary cilium stability but not cilia formation in IMCD3 cells.
Published 2025“…The mean cilia length in CCDC66-depleted cells decreased to 0.67-fold compared to the mean control length. …”
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19305
a. How various statistical models account for modulation classification performance across the entire dataset.
Published 2025“…Vertical lines show the peak-to-trough heights extracted for each significant peak, in order of decreasing value; <b>e.…”
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19306
Table 1_Long-term oyster shell powder applications increase crop yields and control soil acidity and cadmium in red soil drylands.docx
Published 2025“…<p>The intensification of agricultural production has significantly reduced land availability, necessitating continuous cropping cycles that degrade soil quality and inhibit crop growth. …”
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19307
Table 9_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis...
Published 2024“…On multivariable analysis of donkeys, decreased odds of seropositivity were demonstrated amongst donkeys owned by households which also owned horses (OR = 0.23 95% CI 0.06–0.85, p = 0.03). …”
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19308
Data Sheet 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.xlsx
Published 2025“…Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…”
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19309
Table 1_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis...
Published 2024“…On multivariable analysis of donkeys, decreased odds of seropositivity were demonstrated amongst donkeys owned by households which also owned horses (OR = 0.23 95% CI 0.06–0.85, p = 0.03). …”
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19310
Table 2_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis...
Published 2024“…On multivariable analysis of donkeys, decreased odds of seropositivity were demonstrated amongst donkeys owned by households which also owned horses (OR = 0.23 95% CI 0.06–0.85, p = 0.03). …”
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19311
Table 10_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis...
Published 2024“…On multivariable analysis of donkeys, decreased odds of seropositivity were demonstrated amongst donkeys owned by households which also owned horses (OR = 0.23 95% CI 0.06–0.85, p = 0.03). …”
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19312
Table 3_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis...
Published 2024“…On multivariable analysis of donkeys, decreased odds of seropositivity were demonstrated amongst donkeys owned by households which also owned horses (OR = 0.23 95% CI 0.06–0.85, p = 0.03). …”
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19313
Table 8_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis...
Published 2024“…On multivariable analysis of donkeys, decreased odds of seropositivity were demonstrated amongst donkeys owned by households which also owned horses (OR = 0.23 95% CI 0.06–0.85, p = 0.03). …”
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19314
Table 6_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis...
Published 2024“…On multivariable analysis of donkeys, decreased odds of seropositivity were demonstrated amongst donkeys owned by households which also owned horses (OR = 0.23 95% CI 0.06–0.85, p = 0.03). …”
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19315
Table 5_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis...
Published 2024“…On multivariable analysis of donkeys, decreased odds of seropositivity were demonstrated amongst donkeys owned by households which also owned horses (OR = 0.23 95% CI 0.06–0.85, p = 0.03). …”
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19316
Table 4_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis...
Published 2024“…On multivariable analysis of donkeys, decreased odds of seropositivity were demonstrated amongst donkeys owned by households which also owned horses (OR = 0.23 95% CI 0.06–0.85, p = 0.03). …”
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19317
Table 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.docx
Published 2025“…Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…”
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19318
Table 7_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis...
Published 2024“…On multivariable analysis of donkeys, decreased odds of seropositivity were demonstrated amongst donkeys owned by households which also owned horses (OR = 0.23 95% CI 0.06–0.85, p = 0.03). …”
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19319
Supplementary Material for: Genetic characterization of 128 Chinese individuals with neurodevelopmental disorders via whole-exome sequencing
Published 2025“…Introduction: Neurodevelopmental disorders (NDDs) are chronic conditions marked by abnormal brain development, presenting with significant clinical heterogeneity. Early diagnosis is crucial but challenging due to the complex symptoms. …”
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19320
Table 1_Be-SNAP: the Belgian Sepsis National Action Plan.docx
Published 2025“…<p>Sepsis represents a significant healthcare challenge in Belgium with an estimated 40,952 cases annually (95% CI 31,938–54,451). …”