Showing 20,261 - 20,280 results of 21,342 for search '(( significant decrease decrease ) OR ( significant challenges decrease ))', query time: 0.46s Refine Results
  1. 20261

    Image 3_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg by Bing Gu (276393)

    Published 2025
    “…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”
  2. 20262

    Data Sheet 1_Early coronary angiography in patients with myocardial infarction without ST elevation after out-of-hospital cardiac arrest: a systematic review and meta-analysis.pdf by Warda Ahmed (5593586)

    Published 2024
    “…Observational study subgroup showed decreased short-term mortality, long-term mortality, and CPC 1–2 at discharge, unlike RCT subgroup. …”
  3. 20263

    Supplementary file 1_Bioactive fraction isolated from Curcuma angustifolia rhizome exerts anti-diabetic effects in vitro, in silico and in vivo by regulating AMPK/PKA signaling pat... by P. Kavya (21356483)

    Published 2025
    “…After 28 days of intervention, the lower and higher doses of the bioactive fraction (100 and 200 mg/kg BW) substantially decreased fasting blood glucose levels and ameliorated hyperglycemia, glucose intolerance, insulin resistance, and hyperlipidemia. …”
  4. 20264

    Data Sheet 1_Effect of cultivation feed diet using local food processing by-products on the growth and flavor factor in the Malabar grouper Epinephelus malabaricus.docx by Makoto Takahashi (386772)

    Published 2025
    “…FW-D-fed fish also exhibited significantly increased muscle levels of unsaturated fatty acids, particularly docosahexaenoic acid (DHA), a nutrient beneficial for human health. …”
  5. 20265

    Data Sheet 1_Total flavonoids isolated from Eucommia ulmoides can alleviate bone loss and regulate intestinal microbiota in ovariectomized rats.docx by Baocang Yin (20689031)

    Published 2025
    “…</p>Results<p>Oral administration of TFEL for 13 weeks increased the serum level of bone formation marker PINP and decreased the level of bone resorption marker NTX-I. …”
  6. 20266

    Data Sheet 1_Polydopamine nanoparticles as immunomodulators: inhibition of M1 microglial polarization.docx by Maria Cristina Ceccarelli (19233688)

    Published 2025
    “…To mimic neuroinflammatory conditions, HMC3 cells were stimulated with interferon-gamma (IFN-γ), which significantly increased intracellular ROS levels, surface expression of CD40 and CD86, and secretion of pro-inflammatory cytokines. …”
  7. 20267

    Image_1_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg by Katrina S. Hofstetter (17545425)

    Published 2024
    “…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”
  8. 20268

    Table 1_Effects of biochar on phosphorus fraction, phosphatase activity, and phosphorus-solubilizing bacterial abundance: a phosphorus-depleted biochar design.docx by Hongyi Qin (5943515)

    Published 2025
    “…PDB did not significantly alter PSB diversity.</p>Conclusion<p>Phosphorus-depleted biochar reduces potentially available phosphorus fractions and mitigates phosphorus leaching, supporting aquatic ecosystem protection. …”
  9. 20269
  10. 20270

    Image 4_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg by Jie Li (15030)

    Published 2025
    “…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …”
  11. 20271

    Supplementary file 5_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx by Yuhui Zhang (399617)

    Published 2025
    “…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
  12. 20272

    Image 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.tif by Yan Cheng (149222)

    Published 2025
    “…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”
  13. 20273

    Table 1_Co-frequency or contrary? The effects of Qiwei Baizhu Powder and its bioactive compounds on mucosa-associated microbiota of mice with antibiotic-associated diarrhea.docx by Zeli Zhang (3422570)

    Published 2024
    “…The results showed that QWBZP-TG significantly altered the diversity, structure, and abundance of MAM in the AAD mice. …”
  14. 20274

    Table 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx by Yihan Liu (2258221)

    Published 2025
    “…</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …”
  15. 20275

    Data Sheet 2_CqHKT1 and CqSOS1 mediate genotype-dependent Na+ exclusion under high salinity conditions in quinoa.pdf by Yasufumi Kobayashi (5481530)

    Published 2025
    “…By contrast, K<sup>+</sup> accumulation was slightly reduced in the aerial parts but significantly decreased in the roots of all the genotypes. …”
  16. 20276

    Presentation 1_Ischemia-reperfusion injury with a model of porcine whole-blood ex-vivo lung perfusion.pptx by Jean-Baptiste Menager (22163560)

    Published 2025
    “…Interleukin-6 and −8 levels after 6 h were significantly higher in the long CIT group (mean differences, 1.1 pg/ml; 95% CI, 0.39–1.8; P = 0.003; and 29.31 pg/ml; 95%CI, 16.00–42.61; P < 0.001; respectively). …”
  17. 20277

    Image 1_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg by Bing Gu (276393)

    Published 2025
    “…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”
  18. 20278

    Image 2_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif by Asma Bibi (12057986)

    Published 2025
    “…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …”
  19. 20279

    Image 1_Study on the ecosystem service flow based on the relationship of between supply and demand in Yangtze River Economic Belt.jpeg by Ming Lei (161082)

    Published 2024
    “…The study of the supply of ecosystem services and the demand and consumption of ecosystem services by human society, and the analysis of the supply and demand characteristics and flow relationships of ecosystem service flows are of great significance for the management of regional ecosystems and the development of ecological compensation. …”
  20. 20280

    Image 2_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg by Jie Li (15030)

    Published 2025
    “…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …”