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significant challenges » significant challenge (Expand Search), significant changes (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
challenges decrease » challenges case (Expand Search)
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18501
Supplementary file 1_The effect of probiotics on the diarrhea and constipation outcomes in children: an umbrella review of systematic reviews and meta-analyses.docx
Published 2025“…Also, it is successful in reducing diarrhea duration [weighted mean difference (WMD) = −1.85; 95% CI: −2.83, −0.86] and [standardized mean difference (SMD) = −0.94; 95% CI: −1.32, −0.56] significantly. Moreover, probiotics supplementation resulted in decreased stool frequency (WMD = −0.21; 95% CI: −0.37, −0.04). …”
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18502
Table1_Adverse event profile differences between pralsetinib and selpercatinib: a real-world study based on the FDA adverse events reporting system.docx
Published 2024“…The risk of AEs such as decreased platelet count, anemia, decreased white blood cell count, pneumonitis, asthenia, and edema caused by pralsetinib is significantly higher than that of selpercatinib. …”
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18503
Data Sheet 1_CD46 TREM1 regulates the autophagy marker LC3B ATG5 in oral squamous cell carcinoma.docx
Published 2025“…In vivo experiments showed that the tumor volume of the shRNA group was significantly smaller than that of the SC-shRNA group (P<0.01), the expression of CD46 and TREM1 was decreased considerably, and the expression of LC3B and ATG5 was higher (P<0.01). …”
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18504
Data Sheet 1_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.docx
Published 2025“…The respiratory microbiome structure in children with IAV, including H1N1 and H3N2, was significantly different from that of the control, with significantly increased Chao index. …”
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18505
Image 2_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg
Published 2025“…The respiratory microbiome structure in children with IAV, including H1N1 and H3N2, was significantly different from that of the control, with significantly increased Chao index. …”
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18506
Image 5_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg
Published 2025“…The respiratory microbiome structure in children with IAV, including H1N1 and H3N2, was significantly different from that of the control, with significantly increased Chao index. …”
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18507
Hair-follicle-associated pluripotent (HAP) stem-cell-sheet implantation accelerates cutaneous wound closure and suppresses scar formation in a mouse model
Published 2025“…Expression levels of TGF-β1, COL1A2 and COL3A1 mRNA in the wound were significantly decreased in HAP stem cell-implanted mice compared with non-implanted control mice. …”
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18508
Data Sheet 1_Influence of specific tobacco endophytic Bacillus on tobacco leaf quality enhancement during fermentation.pdf
Published 2024“…Chemical analysis revealed that fermentation with B. halotolerans NS36 significantly decreased the content of irritant compounds such as lignin, cellulose, starch, and pectin. …”
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18509
Image 6_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg
Published 2025“…The respiratory microbiome structure in children with IAV, including H1N1 and H3N2, was significantly different from that of the control, with significantly increased Chao index. …”
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18510
Image 4_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg
Published 2025“…The respiratory microbiome structure in children with IAV, including H1N1 and H3N2, was significantly different from that of the control, with significantly increased Chao index. …”
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18511
Image 3_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg
Published 2025“…The respiratory microbiome structure in children with IAV, including H1N1 and H3N2, was significantly different from that of the control, with significantly increased Chao index. …”
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18512
Image2_Adverse event profile differences between pralsetinib and selpercatinib: a real-world study based on the FDA adverse events reporting system.TIF
Published 2024“…The risk of AEs such as decreased platelet count, anemia, decreased white blood cell count, pneumonitis, asthenia, and edema caused by pralsetinib is significantly higher than that of selpercatinib. …”
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18513
Table2_Adverse event profile differences between pralsetinib and selpercatinib: a real-world study based on the FDA adverse events reporting system.docx
Published 2024“…The risk of AEs such as decreased platelet count, anemia, decreased white blood cell count, pneumonitis, asthenia, and edema caused by pralsetinib is significantly higher than that of selpercatinib. …”
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18514
Image 1_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg
Published 2025“…The respiratory microbiome structure in children with IAV, including H1N1 and H3N2, was significantly different from that of the control, with significantly increased Chao index. …”
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18515
Image1_Adverse event profile differences between pralsetinib and selpercatinib: a real-world study based on the FDA adverse events reporting system.TIF
Published 2024“…The risk of AEs such as decreased platelet count, anemia, decreased white blood cell count, pneumonitis, asthenia, and edema caused by pralsetinib is significantly higher than that of selpercatinib. …”
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18516
SEAwise report on the impact of socioeconomic effects of fisheries management adapted according to input from review workshops
Published 2025“…For demersal fleets, variable prices caused significant income shifts, though operational effort was independent of price. …”
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18517
Supplementary file 1_An expert patient program for people living with multiple sclerosis improves knowledge and empowerment: a pre-test, post-test multicenter implementation study....
Published 2025“…Lifestyle habits remained mostly unchanged, except for medication self-management and diet, whereas visits to nurses and other professionals in MS units significantly decreased. Physical health composite scores in the MS quality of life-54 questionnaire decreased, while the mental health composite scores remained unchanged. …”
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18518
Data Sheet 1_Pseudomonas oryzihabitans D1-104/3 and P. gessardii C31-106/3 differentially modulate the antioxidative response of duckweed (Lemna minor L.) to salt stress.docx
Published 2024“…The doubling time of duckweeds inoculated with P. gessardii C31-106/3 was significantly longer. Additionally, at 0 and 10 mM NaCl, this strain decreased chlorosis in duckweeds. …”
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18519
Data Sheet 1_Effects of different fermentation temperatures on microbiomes of cigar tobacco leaves.pdf
Published 2025“…As the temperature increased, the relative abundance of Staphylococcus decreased first and then increased (46.1%–98.5%), while that of Aspergillus increased first and then decreased (34.9%–77.4%). …”
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18520
Table 8_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…Following CX3CR1 knockout in the middle-aged mice, TNF-α and IL-1α levels increased, while CD68, SRA, and RAGE levels decreased in the hippocampus. Similarly, CD68, CD36, SRB1, and RAGE levels decreased in the frontal cortex. …”