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significant challenges » significant challenge (Expand Search), significant changes (Expand Search)
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challenges decrease » challenges case (Expand Search)
significant challenges » significant challenge (Expand Search), significant changes (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
challenges decrease » challenges case (Expand Search)
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1301
Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation
Published 2024“…Although the development of DYRK1A inhibitors has significantly advanced in recent years, the selectivity of these drugs remains a critical challenge, potentially impeding further progress. …”
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1302
Data for Moreno and Teixido. 2025. Journal of Animal Ecology
Published 2025“…Behaviour also showed an increase in negative impacts and a decrease in positive impacts in invertebrates compared to vertebrates.. …”
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1303
<b>Artificial cilia for </b><b>360° </b><b>direction-sensitive acoustic</b><b> sensing</b><b> through additive micromanufacturing</b>
Published 2025“…The response of the artificial cilia at resonance is significantly enhanced, while the resonance frequencies decrease with increasing length. …”
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1304
Data Sheet 1_Convolutional neural networks decode finger movements in motor sequence learning from MEG data.docx
Published 2025“…</p>Results<p>Sequence learning was reflected by a decrease in reaction times during SRTT performance. …”
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1305
Image 1_Emapalumab for severe cytokine release syndrome in solid tumor CAR-T: a case report.tif
Published 2025“…The hemodynamic improvement was associated with a decrease in IFN-γ and CXCL10 levels but no other cytokines. …”
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1306
Actual Vs predicted revenue.
Published 2025“…On the Reddit dataset, MSE and MAPE decrease by 6.6% and 5.3%, respectively, and improves to 0.854. …”
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1307
Data Sheet 1_Treatment of bacterial biothreat agents with a novel purified bioactive lactoferrin affects both growth and biofilm formation.docx
Published 2025“…Here, we show that Lactea Lf can significantly inhibit biofilm and decrease the overall growth in a dose dependent manner for all Burkholderia species tested. …”
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1308
Data Sheet 1_Analysis of serum amino acids and tryptophan metabolites to predict hepatic encephalopathy in portal hypertension patients receiving a transjugular intrahepatic portal...
Published 2025“…Introduction<p>The incidence of hepatic encephalopathy (HE) after transjugular intrahepatic portal shunt (TIPS) is over 30%, how to decrease the occurrence rate of HE is one of the most challenging issues after TIPS surgery. …”
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1309
Overview design of F-TransR model architecture.
Published 2025“…On the Reddit dataset, MSE and MAPE decrease by 6.6% and 5.3%, respectively, and improves to 0.854. …”
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1310
F-TransR experimental effect diagram.
Published 2025“…On the Reddit dataset, MSE and MAPE decrease by 6.6% and 5.3%, respectively, and improves to 0.854. …”
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1311
F-TransR rendering after removing some modules.
Published 2025“…On the Reddit dataset, MSE and MAPE decrease by 6.6% and 5.3%, respectively, and improves to 0.854. …”
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1312
RE-AIM indicators.
Published 2025“…If successful, this model can significantly improve stillbirth prevention in low-resource settings.…”
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1313
Logic model based on ERIC-CFIR.
Published 2025“…If successful, this model can significantly improve stillbirth prevention in low-resource settings.…”
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1314
Presentation 4_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-ser...
Published 2025“…The persistent rise in hospital admissions for mental health disorders, particularly teenage girls, make this field a challenging, absolute priority for public health.</p>…”
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1315
Presentation 1_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-ser...
Published 2025“…The persistent rise in hospital admissions for mental health disorders, particularly teenage girls, make this field a challenging, absolute priority for public health.</p>…”
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1316
Data Sheet 1_Chemopreventive and therapeutic effects of Hippophae rhamnoides L. fruit peels evaluated in preclinical models of breast carcinoma.docx
Published 2025“…In the 4T1 mouse model, seaberry treatment resulted in a significant, dose-dependent reduction in tumor volume (43% and 48% compared to controls) and a decrease in the mitotic activity index. …”
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1317
Presentation 3_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-ser...
Published 2025“…The persistent rise in hospital admissions for mental health disorders, particularly teenage girls, make this field a challenging, absolute priority for public health.</p>…”
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1318
Table 1_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-series ana...
Published 2025“…The persistent rise in hospital admissions for mental health disorders, particularly teenage girls, make this field a challenging, absolute priority for public health.</p>…”
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1319
Presentation 2_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-ser...
Published 2025“…The persistent rise in hospital admissions for mental health disorders, particularly teenage girls, make this field a challenging, absolute priority for public health.</p>…”
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1320
Image 4_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.jpeg
Published 2024“…MiR-936 overexpression and GV102-Pim-3-shRNA significantly attenuated the activity of the ANKRD18A/Src/NRF2 pathway to decrease the expression of Ankyrin repeat domain-containing protein 18A (ANKRD18A), Src, and Nuclear factor (erythroid-derived 2)-like 2 (NRF2), especially decreasing NRF2 nuclear retention and transcriptional activity. …”