Table 2_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.xlsx by Lisheng Xiao (15919517)

“…Going beyond the general knowledge that hypermucoviscosity (HMV) mediates high virulence, we observed that deficits in ptsI and GM2628 led to HMV while decreasing virulence. This exemplifies that HMV does not always directly correlate with virulence, challenging its role as a virulence marker and underscoring the need for further investigation into non-HMV-mediated virulence mechanisms.…”

Raw data of influencing factors. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Supplementary Material for: A Case Report of Intravitreal Aflibercept for Iris Metastasis from Small Cell Lung Carcinoma with Neovascular Glaucoma by figshare admin karger (2628495)

“…Abstract Introduction Metastatic iris tumors from lung cancer are uncommon and challenging to diagnose. As lung cancer treatments improve, life expectancy increases, potentially leading to more cases of metastasis. …”

Evaluation standards of the CCD. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Direct and indirect effects. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

Image 2_Computed tomography and magnetic resonance imaging features of primary liver perivascular epithelioid cell tumor with renal angiomyolipoma: a case report and literature rev... by Ruoling Gao (12201178)

“…The enhancement slightly decreased in the equilibrium phase and the delayed phase. …”

Table 2_Adherence to recombinant human growth hormone therapy in children: influencing factors and clinical implications.xlsx by Wenjing Chang (8334480)

“…However, non-adherence remains a significant challenge, affecting treatment efficacy and patient prognosis. …”

Coupling degree results. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Carbon productivity results. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Table 1_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.xlsx by Lisheng Xiao (15919517)

“…Going beyond the general knowledge that hypermucoviscosity (HMV) mediates high virulence, we observed that deficits in ptsI and GM2628 led to HMV while decreasing virulence. This exemplifies that HMV does not always directly correlate with virulence, challenging its role as a virulence marker and underscoring the need for further investigation into non-HMV-mediated virulence mechanisms.…”

Digital infrastructure results. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Table 1_Molecular and epigenetic responses to crowding stress in rainbow trout (Oncorhynchus mykiss) skeletal muscle.xlsx by Daniela Aravena-Canales (14336037)

“…Background<p>Chronic stress is a critical challenge in fish aquaculture, adversely affecting growth, health, and overall productivity. …”

Divergent Oncogenic Signaling and Immune Microenvironment Changes in Low-Grade Serous Ovarian Cancer Undergoing Intraperitoneal Treatment by Isaac Bishara (21157583)

“…<p dir="ltr">Low-grade serous ovarian carcinoma (LGSOC) is a rare, therapeutically challenging subtype of epithelial ovarian cancer characterized by high recurrence rates and intrinsic resistance to conventional therapies. …”

Image 1_Computed tomography and magnetic resonance imaging features of primary liver perivascular epithelioid cell tumor with renal angiomyolipoma: a case report and literature rev... by Ruoling Gao (12201178)

“…The enhancement slightly decreased in the equilibrium phase and the delayed phase. …”

Coupling coordination degree results. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Table 1_Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations.docx by Juan Liu (6492)

“…Introduction<p>The emergence of the wide variety of novel tigecycline resistance tet(X) variants, including tet(X3), tet(X4), tet(X5), and tet(X6), has raised a serious threat to global public health and posed a significant challenge to the clinical treatment of multidrug-resistant bacterial infections.…”

Table 1_Adherence to recombinant human growth hormone therapy in children: influencing factors and clinical implications.xlsx by Wenjing Chang (8334480)

“…However, non-adherence remains a significant challenge, affecting treatment efficacy and patient prognosis. …”

Table 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.xlsx by Xiaofang Guo (385478)

“…Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. …”

Economic resilience results. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”