Showing 1,741 - 1,760 results of 2,040 for search '(( significant decrease decrease ) OR ( significant challenges decrease ))~', query time: 0.26s Refine Results
  1. 1741

    Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx by Mattia Dalle Nogare (22696022)

    Published 2025
    “…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”
  2. 1742

    Video 5_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4 by Shirong Ruan (15414081)

    Published 2024
    “…Background<p>Neuropathic pain (NPP) is a multifaceted pain syndrome that occurs as a consequence of physical injury or underlying diseases, with an incidence rate of 7%-10%, NPP poses a significant clinical challenge as current treatment options are ineffective. …”
  3. 1743

    Image 2_Exploring the antibacterial and anti-biofilm properties of Diacerein against methicillin-resistant Staphylococcus aureus.tif by Yingying Sun (568696)

    Published 2025
    “…Background<p>Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant clinical challenge due to its multidrug resistance. …”
  4. 1744

    Video 6_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4 by Shirong Ruan (15414081)

    Published 2024
    “…Background<p>Neuropathic pain (NPP) is a multifaceted pain syndrome that occurs as a consequence of physical injury or underlying diseases, with an incidence rate of 7%-10%, NPP poses a significant clinical challenge as current treatment options are ineffective. …”
  5. 1745

    Table 6_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xls by Ahmet Alptekin (14937405)

    Published 2025
    “…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”
  6. 1746

    Table 4_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xls by Ahmet Alptekin (14937405)

    Published 2025
    “…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”
  7. 1747

    Supplementary file 1_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.pdf by Ahmet Alptekin (14937405)

    Published 2025
    “…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”
  8. 1748

    Table 3_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xlsx by Ahmet Alptekin (14937405)

    Published 2025
    “…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”
  9. 1749

    Table 1_Decadal trends and regional disparities in tuberculosis burden: a comprehensive analysis of global, African, and Southeast Asian data from the GBD 1990–2021.docx by Shiwei Xie (3617159)

    Published 2025
    “…The annual percentage change (APC) was calculated to assess the significance of temporal trends.</p>Results<p>From 1990 to 2021, global age-standardized rates of TB declined markedly, with ASIR decreasing from 173.0 to 103.0 per 100,000, ASMR from 40.0 to 14.0, and ASDR from 1,650.6 to 580.3. …”
  10. 1750

    Table 2_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xls by Ahmet Alptekin (14937405)

    Published 2025
    “…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”
  11. 1751

    Data Sheet 1_Analysis of temporal and spatial changes in the global burden of hypertensive heart disease based on data from the Global Burden of Disease study database and future p... by Guoliang Gao (2910503)

    Published 2025
    “…According to the APC model, the worldwide incidence of hypertensive heart disease is expected to increase from 2022 to 2046, with further decreases in deaths and DALYs.</p>Conclusions<p>This study systematically reveals the increasing trend in the incidence of hypertensive heart disease globally between 1990 and 2021 and confirms the significant impact of sex and socioeconomic development level on its burden. …”
  12. 1752

    Table 1_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xls by Ahmet Alptekin (14937405)

    Published 2025
    “…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”
  13. 1753

    DataSheet1_IVIG response in pediatric acute-onset neuropsychiatric syndrome correlates with reduction in pro-inflammatory monocytes and neuropsychiatric measures.docx by Isaac Melamed (6291590)

    Published 2024
    “…The fraction of pro-inflammatory monocytes and dendritic cells decreased from pre-IVIG treatment levels. The proportional reductions were not compensated by increases in total white blood cells; pro-inflammatory monocytes post-IVIG were decreased as a proportion of CD14+ myeloid cells and in absolute number.…”
  14. 1754

    Table 5_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xlsx by Ahmet Alptekin (14937405)

    Published 2025
    “…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”
  15. 1755

    C2f and BC2f module structure diagrams. by Yaojun Zhang (389482)

    Published 2025
    “…Existing methods encounter challenges like intricate detection environments, small-scale targets, and extensive model parameters. …”
  16. 1756

    YOLOv8n detection results diagram. by Yaojun Zhang (389482)

    Published 2025
    “…Existing methods encounter challenges like intricate detection environments, small-scale targets, and extensive model parameters. …”
  17. 1757

    YOLOv8n-BWG model structure diagram. by Yaojun Zhang (389482)

    Published 2025
    “…Existing methods encounter challenges like intricate detection environments, small-scale targets, and extensive model parameters. …”
  18. 1758

    Data Sheet 1_Instructors as communication strategists: using multimodal communication to implement a new course policy on assignment extension due dates.docx by Joseph M. Ruesch (18194605)

    Published 2025
    “…Increasing the number of communication channels decreased the confusion about the extension policies. …”
  19. 1759

    BiFormer structure diagram. by Yaojun Zhang (389482)

    Published 2025
    “…Existing methods encounter challenges like intricate detection environments, small-scale targets, and extensive model parameters. …”
  20. 1760

    YOLOv8n-BWG detection results diagram. by Yaojun Zhang (389482)

    Published 2025
    “…Existing methods encounter challenges like intricate detection environments, small-scale targets, and extensive model parameters. …”