يعرض 20,581 - 20,600 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant change decrease ))', وقت الاستعلام: 0.49s تنقيح النتائج
  1. 20581

    Table 1_Supplementation of Yupingfeng polysaccharides in low fishmeal diets enhances intestinal health through influencing the intestinal barrier, immunity, and microflora in Macro... حسب Mingyang Liu (426690)

    منشور في 2024
    "…</p>Results<p>The LF diet significantly reduced growth performance parameters compared to the control group. …"
  2. 20582

    Table 5_Ten-year outcomes of repeat keratoplasty for optical indications.docx حسب Victoria Grace Dimacali (20597690)

    منشور في 2025
    "…Cox multiple regression analysis showed male gender (p = 0.023), PK regraft (p = 0.003), regraft rejection (p = 0.003), and initial graft indications of pseudophakic bullous keratopathy (p = 0.005) and aphakic bullous keratopathy (p = 0.004) to be risk factors for regraft failure, while longer time to regraft was associated with decreased risk of failure (p = 0.013).</p>Conclusion<p>Performing EK for failed optical PK or EK significantly improved regraft survival compared to repeat PK. …"
  3. 20583

    Data Sheet 1_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.docx حسب Wenjing Xue (2880686)

    منشور في 2025
    "…GO and KEGG analyses indicated that QgYp significantly affects TGF-β signaling pathway. In addition, the results of qPCR and Western blot analysis from both in vitro and in vivo experiments indicated that QgYp significantly downregulated the expression of proteins and mRNA associated with the TGF-β1/Smad2/3 pathway. …"
  4. 20584

    Image 2_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif حسب Toru Miwa (8528715)

    منشور في 2025
    "…Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …"
  5. 20585

    Image 3_Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets.tif حسب Jie Chong (18433611)

    منشور في 2025
    "…The results demonstrated that HDCA administration at 0.2 mg/mL suppressed body weight gain in piglets, which was alleviated by FMT. HDCA significantly altered gut microbiota composition in SPF piglets, markedly increasing the Lactobacillus abundance (37.97% vs. 5.28% in SPF-CON) while decreasing the proportion of Streptococcus (28.34% vs. 38.65%) and pathogenic family Erysipelotrichaceae (0.35% vs. 17.15%). …"
  6. 20586

    Data Sheet 3_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for... حسب Shen Tian (4424170)

    منشور في 2025
    "…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.</p>Conclusion<p>From 1990 to 2021, the global CRC burden increased significantly, with notable variations across SDI regions. …"
  7. 20587

    <i>DANCR</i> regulated genes in SK-MEL-28 cells. حسب Stephanie M. E. Jones (12883691)

    منشور في 2025
    "…MITF and c-MYC, key melanoma transcription factors, regulate human <i>DANCR</i> expression and melanoma patients with high <i>DANCR</i> display significantly decreased survival. <i>DANCR</i> is a melanoma oncogene that controls cancer-associated gene expression networks to promote human melanoma cell proliferation and migration. …"
  8. 20588

    Image 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.tif حسب Jing Lv (128179)

    منشور في 2025
    "…In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …"
  9. 20589

    Data Sheet 1_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for... حسب Shen Tian (4424170)

    منشور في 2025
    "…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.</p>Conclusion<p>From 1990 to 2021, the global CRC burden increased significantly, with notable variations across SDI regions. …"
  10. 20590

    Data Sheet 10_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip... حسب Chutian Zhang (10732350)

    منشور في 2025
    "…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"
  11. 20591

    Table_1_RETRACTED: miR-335 Targets LRRK2 and Mitigates Inflammation in Parkinson’s Disease.DOCX حسب Sara R. Oliveira (10972152)

    منشور في 2025
    "…LRRK2-Wt-induced proinflammatory gene expression was also significantly reduced by miR-335 overexpression. Finally, in SH-SY5Y neuroblastoma cells, miR-335 decreased the expression of pro-inflammatory genes triggered by α-synuclein. …"
  12. 20592

    Table 2_Causality of genetically determined serum metabolites on lower back pain or/and sciatica: a comprehensive Mendelian randomized study.docx حسب Yi-Ming Ren (555968)

    منشور في 2024
    "…Among them, 8 serum metabolites decreased risk of sciatica or/and lower back pain significantly (P < 0.05), and 14 serum metabolites increased risk of sciatica or/and lower back pain significantly (P < 0.05). …"
  13. 20593

    Table 2_Ten-year outcomes of repeat keratoplasty for optical indications.docx حسب Victoria Grace Dimacali (20597690)

    منشور في 2025
    "…Cox multiple regression analysis showed male gender (p = 0.023), PK regraft (p = 0.003), regraft rejection (p = 0.003), and initial graft indications of pseudophakic bullous keratopathy (p = 0.005) and aphakic bullous keratopathy (p = 0.004) to be risk factors for regraft failure, while longer time to regraft was associated with decreased risk of failure (p = 0.013).</p>Conclusion<p>Performing EK for failed optical PK or EK significantly improved regraft survival compared to repeat PK. …"
  14. 20594

    Data Sheet 13_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip... حسب Chutian Zhang (10732350)

    منشور في 2025
    "…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"
  15. 20595

    Data Sheet 1_Characterization of Ty21a immunostimulatory effects in the mouse bladder.pdf حسب Lenka Polak (17777406)

    منشور في 2025
    "…Indeed, CD8<sup>+</sup> T-cell infiltration following Ty21a<sup>FR</sup> was significantly decreased in TLR4- and MyD88-KO mice. In contrast, myeloid-cell recruitment was only reduced in MyD88-KO mice, suggesting the involvement of TLR4-independent pathways in that process. …"
  16. 20596

    Image 2_CD155 as a therapeutic target in alveolar echinococcosis: insights from an Echinococcus multilocularis infection mouse model.tif حسب Xue Zhang (166886)

    منشور في 2025
    "…</p>Results<p>CD155 expression in hepatocytes was significantly increased—approximately 2-fold compared to Sham controls—and predominantly localized near lesion sites. …"
  17. 20597

    Data Sheet 4_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip حسب Chutian Zhang (10732350)

    منشور في 2025
    "…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"
  18. 20598

    Data Sheet 7_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip حسب Chutian Zhang (10732350)

    منشور في 2025
    "…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"
  19. 20599

    Data Sheet 1_Preventive hyperbaric oxygen therapy improves acute graft-versus-host disease by activating the Nrf2/HO-1 pathway.pdf حسب Chao Xue (503328)

    منشور في 2025
    "…HBOT decreased ROS levels and proinflammatory cytokines, including IL-6 and TNF-α, while upregulated Nrf2 and its downstream antioxidant enzyme HO-1. …"
  20. 20600

    Data Sheet 3_Causality of genetically determined serum metabolites on lower back pain or/and sciatica: a comprehensive Mendelian randomized study.xlsx حسب Yi-Ming Ren (555968)

    منشور في 2024
    "…Among them, 8 serum metabolites decreased risk of sciatica or/and lower back pain significantly (P < 0.05), and 14 serum metabolites increased risk of sciatica or/and lower back pain significantly (P < 0.05). …"