Supplementary Material for: Focus on the Blind Spot of Stone Disease: Analysis of Lower Urinary Tract Stone Interventions from 2006 to 2020 using German nationwide inpatient data. by Herout R. (20352174)

“…Methods We analyzed data from the nationwide German hospital billing database from 2006 to 2020. The significance of changes over time was evaluated via linear regression analysis. …”

Image 1_Loss of calcium/calmodulin-dependent protein kinase kinase 2, transferrin, and transferrin receptor proteins in the temporal cortex of Alzheimer’s patients postmortem is as... by Mohammad Golam Sabbir (15874493)

“…</p>Results<p>CAMKK2, TF, and TFRC levels were significantly decreased in AD patients’ temporal cortices compared to CN individuals, independent of age or postmortem interval-related changes. …”

Table5_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

Table4_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

Image 2_Loss of calcium/calmodulin-dependent protein kinase kinase 2, transferrin, and transferrin receptor proteins in the temporal cortex of Alzheimer’s patients postmortem is as... by Mohammad Golam Sabbir (15874493)

“…</p>Results<p>CAMKK2, TF, and TFRC levels were significantly decreased in AD patients’ temporal cortices compared to CN individuals, independent of age or postmortem interval-related changes. …”

Image 1_Enhancement of host defense against Helicobacter pylori infection through modulation of the gastrointestinal microenvironment by Lactiplantibacillus plantarum Lp05.tif by Yao Dong (3308124)

“…Lp05 treatment significantly modified the intestinal and gastric microbiota, increasing beneficial bacteria like Lactobacillus and Ligilactobacillus, and decreasing harmful bacteria such as Olsenella, linked to pathological conditions.…”

Table2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

Table3_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

Table 1_Loss of calcium/calmodulin-dependent protein kinase kinase 2, transferrin, and transferrin receptor proteins in the temporal cortex of Alzheimer’s patients postmortem is as... by Mohammad Golam Sabbir (15874493)

“…</p>Results<p>CAMKK2, TF, and TFRC levels were significantly decreased in AD patients’ temporal cortices compared to CN individuals, independent of age or postmortem interval-related changes. …”

Table1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

Table6_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

Image 3_Loss of calcium/calmodulin-dependent protein kinase kinase 2, transferrin, and transferrin receptor proteins in the temporal cortex of Alzheimer’s patients postmortem is as... by Mohammad Golam Sabbir (15874493)

“…</p>Results<p>CAMKK2, TF, and TFRC levels were significantly decreased in AD patients’ temporal cortices compared to CN individuals, independent of age or postmortem interval-related changes. …”

Data Sheet 1_Wilt disease reshapes rhizosphere microbiota in small yellow ginger soils.docx by Qing Sun (492552)

“…</p>Results<p>Ginger wilt disease significantly altered the rhizosphere soil bacterial community structure and composition: the relative abundance of Proteobacteria increased significantly, primarily due to the enrichment of the genus Ralstonia; conversely, the relative abundance of Acidobacteriota, Firmicutes, and Chloroflexi significantly decreased. …”

Figure 5 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6A KO decreases Ewing sarcoma tumor growth. <b>A,</b> Colony formation assay of KDM6A KO cells (sgRNA#1 and sgRNA#2) compared with parental cells and sgCTRL in A-673. …”

Table 1_Integrated gut microbiota and metabolomic profiling reveals key associations between amino acid levels and gut microbial composition in patients with obesity.docx by Musen Qi (22489075)

“…Metabolomic analysis revealed that in patients with obesity, the abundance of carnosine (log2FC = 1.16, FDR = 0.0016, VIP = 0.707), creatinine (log2FC = 0.21, FDR = 0.0009, VIP = 2.02), and cystine (log2FC = 0.55, FDR = 0.009, VIP = 1.47) was significantly increased compared with that in the controls; in contrast, that of ornithine (log2FC = −0.59, FDR = 0.0009, VIP = 1.19), citrulline (log2FC = −0.59, FDR = 0.0003, VIP = 0.707), glycine (log2FC = −0.54, FDR = 0.0003, VIP = 1.41), and serine (log2FC = −0.38, FDR = 0.0019, VIP = 1.62) was significantly decreased. …”

NHR-49/80 mediated FEDUS via the peroxisomal activation. by Meiyu Ruan (19929335)

“…Lower population density significantly decreased palmitic acid-induced AWC maturation. …”

Ca²⁺ homeostasis and the corpuscles of Stannius regulate sensory gating. by Susannah S. Schloss (21238775)

“…<b>(A)</b> Exposure to high (10 mM) Ca²⁺ caused a slight but significant increase in whole-body Ca²⁺ levels, compared to normal 0.33 mM Ca²⁺ (*<i>p</i> = 0.024). …”

<b>Selective Reduction of Ca</b>^{<strong>2+</strong>}<b>-Independent Phospholipase A</b>_{<strong>2</strong>}<b>b</b><b> (iPLA</b>_{<strong>2</strong>}<b>b... by Abdulaziz Almutairi (9584768)

“…</p><p dir="ltr">· Reduction of myeloid-iPLA₂b decreases T1D incidence.</p><p dir="ltr"><br><b>d. …”

Video 2_Assessment of the morphological features, physiological and photosynthetic activity of the different cell forms of Symbiodiniaceae using microfluidic methods.mp4 by Milán Szabó (511040)

“…We found that by the application of Ficoll the diurnal cycle of the different cell forms undergoes remarkable changes, the motility of the cells decreases, and the motile phase of the cell cycle becomes significantly shorter compared to the absence of Ficoll. …”

Video 3_Assessment of the morphological features, physiological and photosynthetic activity of the different cell forms of Symbiodiniaceae using microfluidic methods.mp4 by Milán Szabó (511040)

“…We found that by the application of Ficoll the diurnal cycle of the different cell forms undergoes remarkable changes, the motility of the cells decreases, and the motile phase of the cell cycle becomes significantly shorter compared to the absence of Ficoll. …”