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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant change » significant changes (Expand Search), significant challenge (Expand Search), significant challenges (Expand Search)
change decrease » change increases (Expand Search), change degree (Expand Search)
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19761
Data Sheet 1_STING regulates NETs formation by activating GSDMD in influenza viral pneumonia.pdf
Published 2025“…Symptoms of pneumonia in STING-KO mice infected with PR8 were significantly milder than those in WT mice, and NETs were less likely to form in the lung tissue of STING-KO mice. …”
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19762
Table 3_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx
Published 2025“…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…”
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19763
Image 2_CT angiography-derived three-dimensional pulmonary vein topography is related to the outcome after cryoballoon ablation.tiff
Published 2025“…The number of occlusion attempts in the right inferior PV was significantly higher in the PVI failure group indicating a technical more complex balloon occlusion. …”
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19764
DataSheet1_Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles.docx
Published 2024“…Pharmacokinetic parameters such as AUC<sub>0-t</sub>, C<sub>max</sub> MRT, Vd, and half-life (t<sub>1/2</sub>) were enhanced significantly (p ≤ 0.001), while clearance was considerably decreased (p ≤ 0.001) for the chosen synthesized nanoparticles in contrast to the commercially accessible sorafenib formulation (Nexavar<sup>®</sup>). …”
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19765
Image 4_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti...
Published 2025“…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …”
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19766
Supplementary file 1_The efficacy of resveratrol in the treatment of liver fibrosis: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…</p>Conclusion<p>Resveratrol significantly alleviates liver fibrosis in animal models via anti-inflammatory and antioxidant mechanisms. …”
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19767
Roxadustat alleviates cisplatin-induced acute kidney injury by regulating fatty acid oxidation and mitochondrial function
Published 2025“…Roxadustat also remarkably decreased the expression of KIM-1 and NGAL. Furthermore, roxadustat significantly abolished the expression of Bax and cleaved caspase 3, two apoptosis marker proteins. …”
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19768
Table 4_Outcomes after liposuction-based treatment of lymphedema: a systematic review and meta-analysis.docx
Published 2025“…Combined approaches achieved slightly lower reductions (87.31%), but significantly decreased compression dependence, improved lymphatic function, and enhanced QOL. …”
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19769
Table 1_Evaluation of a multi-epitope vaccine PME for Pasteurella multocida in mouse model.docx
Published 2025“…Furthermore, the pathological lung damages in the His-PME group and the pcDNA3.1-PME group were significantly alleviated, and the bacterial loads in lung tissues were significantly decreased. …”
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19770
Supplementary file 1_Application of multidimensional gait feature fusion algorithm in gait assessment for patients with knee osteoarthritis.docx
Published 2025“…The incorporation of multidimensional features significantly enhanced the performance of all classification models: under multidimensional feature input, RF, SVM, DT, and KNN achieved accuracies of 96.93%, 92.44%, 90.29%, and 88.98%, respectively—all significantly outperforming models using single‐dimensional features.…”
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19771
Image_3_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG
Published 2025“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”
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19772
Supplementary Material for: Seizure Burden Before and After Lidocaine as Add-on Therapy in (a)EEG-Confirmed Neonatal Seizures
Published 2025“…After LDC administration, median TSB decreased significantly from 31 (interquartile range, IQR 16–68) to 0 minutes (IQR 0–0, p<0.01), and MSB from 10 (IQR 6–41) to 0 min/hour (IQR 0–0, p<0.01). …”
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19773
Image 4_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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19774
Image 1_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti...
Published 2025“…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …”
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19775
Image 5_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti...
Published 2025“…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …”
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19776
Data Sheet 1_Lactobacillus paragasseri HM018 derived from breast milk ameliorates hyperlipidemia in high-cholesterol rats by modulating bile acid metabolism.docx
Published 2025“…</p>Results and discussion<p>We established three dosage groups (2.5 × 10<sup>8</sup>, 5 × 10<sup>8</sup>, and 1.5 × 10<sup>9</sup> CFU/rat), demonstrating that HM018 significantly reduced high-fat diet-induced serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, while ameliorating gut microbiota dysbiosis and decreasing the Firmicutes/Bacteroidetes ratio. …”
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19777
Data Sheet 1_Daily online adaptation enhances target coverage in prostate cancer radiotherapy: a retrospective analysis.pdf
Published 2025“…Interquartile ranges decreased across all metrics.</p>Conclusions<p>Adaptation significantly improved target dose metrics compared to non-adapted plans, without compromising organs-at-risk sparing. …”
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19778
Modulating Aesthetic Furniture Preferences through Music: A Multimodal Neurophysiological Study Using Neural Ordinary Differential Equations Networks
Published 2025“…</p><p dir="ltr">The findings revealed that musical intervention significantly modulated neural activity in specific frequency bands: prediction error for tactile density in the Alpha band decreased by 26.9%, while prediction accuracy for exquisiteness in the Beta band improved significantly. …”
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19779
DATA.xlsx
Published 2025“…We found that total ecosystem <sup>15</sup>N recovery was significantly higher under UAN than CAN during early stages (7-120 days), although this difference diminished by 365 days. …”
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19780
Table 3_Outcomes after liposuction-based treatment of lymphedema: a systematic review and meta-analysis.docx
Published 2025“…Combined approaches achieved slightly lower reductions (87.31%), but significantly decreased compression dependence, improved lymphatic function, and enhanced QOL. …”