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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant change » significant changes (Expand Search), significant challenge (Expand Search), significant challenges (Expand Search)
change decrease » change increases (Expand Search), change degree (Expand Search)
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4321
Signal denoising in modular spiking networks
Published 2024“…From providing a structural scaffold for spatial information segregation to the organization of spatiotemporal feature maps, these ubiquitous anatomical features are known to have significant, albeit not entirely understood, functional consequences.…”
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4322
Data_Sheet_1_Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson’s disease.docx
Published 2025“…Using PD patients’ induced-pluripotent stem cells (iPSCs), we examined TFEB activity and regulation of the ALP in dopaminergic neuronal cultures generated from iPSC lines harboring heterozygous GBA1 mutations and the CRISPR/Cas9-corrected isogenic controls. Our data showed a significant decrease in TFEB transcriptional activity and attenuated expression of many genes in the CLEAR network in GBA1 mutant neurons, but not in the isogenic gene-corrected cells. …”
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4323
Data Sheet 1_Metabolism and immune responses of striped hamsters to ectoparasite challenges: insights from transcriptomic analysis.zip
Published 2024“…By day 28, only SOD expression showed a significant decrease in both parasitism groups.</p>Conclusion<p>This study uncovered the dynamic changes in metabolism and immune responses of striped hamsters parasitized by Xenopsylla cheopis. …”
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4324
Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx
Published 2025“…Introduction<p>The potential for drug-induced gastrointestinal (GI) toxicity is significant, since the GI tract is one of the first barriers which come in to contact with oral drugs. …”
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4325
Image 1_Global, regional, and national burden of nutritional deficiencies spanning from 1990 to 2021, with a focus on the impacts observed during the COVID-19 pandemic.tif
Published 2025“…</p>Conclusions<p>Despite a decline in the global burden of nutritional deficiencies over time, significant disparities related to gender, region, and age persist. …”
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4326
<b>A meta-analysis of immediate and delayed discard mortality of red snapper (</b><b><i>Lutjanus campechanus</i></b><b>)</b>
Published 2025“…We assessed if depth, season, release method, or region predict discard mortality. We found a significant positive relationship between depth and discard mortality and that, in the western Gulf, fishing in the summer significantly increases discard mortality compared to fishing in other seasons and regions. …”
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4327
DataSheet1_Effects of pharmacogenomics-guided treatment on medication adherence and the antidepressant switching rate in major depressive disorder.docx
Published 2024“…The difference was also significant after 6 months (38.06% in the PGxT group vs. 24.84% in the TAU group; p < 0.001). …”
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4328
Data_Sheet_1_Effects of a 30-min rest with a nap chair on task performance, sleepiness, and neurophysiological measures in men with suspected brain fatigue: a randomized controlled...
Published 2024“…The Karolinska Sleepiness score significantly decreased after the nap-chair rest, and the between-treatment difference in the decrease was highly significant (P = 0.0004). …”
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4329
Glia-targeted 5-HT<sub>2A</sub> receptor expression in adults reopens experience-dependent synaptic glomeruli pruning.
Published 2024“…There is a significant decrease in the Or42a OSN innervation volume with glial-targeted <i>Gal80</i><sup><i>ts</i></sup><i>-5-HT</i><sub><i>2A</i></sub><i>R</i> OE at 28°C (<i>n</i> = 20/condition, <i>p</i> = 1.00 × 10<sup>−15</sup>). …”
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4330
Image 1_Elevated thiamine level is associated with activating interaction between HIF-1α and SLC19A3 in experimental myopic guinea pigs.jpeg
Published 2025“…</p>Results<p>Compared with the normal control (NC) group, the LIM group guinea pigs showed a significant increase in axial length and decrease in refractive error, as well as a thinning of choroidal thickness and loosening of tissue structure. …”
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4331
Table 2_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx
Published 2025“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”
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4332
Table 6_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx
Published 2025“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”
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4333
Table 3_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx
Published 2025“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”
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4334
Table 1_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx
Published 2025“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”
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4335
Table 5_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx
Published 2025“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”
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4336
Table 4_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx
Published 2025“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”
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4337
Table 6_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.xlsx
Published 2025“…The overall percentage of activated MCs in ccRCC tissues did not change significantly but shifted toward a more activated subpopulation (VEGFA<sup>+</sup> MCs), with a concomitant decrease in proliferative MCs (TNF<sup>+</sup> MCs) and resting MCs. …”
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4338
Image 1_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.jpeg
Published 2025“…The overall percentage of activated MCs in ccRCC tissues did not change significantly but shifted toward a more activated subpopulation (VEGFA<sup>+</sup> MCs), with a concomitant decrease in proliferative MCs (TNF<sup>+</sup> MCs) and resting MCs. …”
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4339
Table 1_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.xlsx
Published 2025“…The overall percentage of activated MCs in ccRCC tissues did not change significantly but shifted toward a more activated subpopulation (VEGFA<sup>+</sup> MCs), with a concomitant decrease in proliferative MCs (TNF<sup>+</sup> MCs) and resting MCs. …”
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4340
Image 4_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.jpeg
Published 2025“…The overall percentage of activated MCs in ccRCC tissues did not change significantly but shifted toward a more activated subpopulation (VEGFA<sup>+</sup> MCs), with a concomitant decrease in proliferative MCs (TNF<sup>+</sup> MCs) and resting MCs. …”